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599 articles for “Soft”
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Integrating Network Pharmacology and Molecular Docking to Assess Rutin’s Pharmacological Properties
Abstract: Objectives: In the present research, the network pharmacology process was applied to determine the underlying mechanism of the pharmacological properties of Rutin. Network pharmacology was utilized to reveal the interactions between medications and the targets of illnesses, and it is capable of completely articulating the complexity between diseases and medications. The identification of diverse drug-target interactions using network pharmacology may be utilized to discover novel medications for difficult conditions like …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 20–33 Read article
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Breast Feeding Practices Among Rural Women
Abstract: Introduction: Breastfeeding is an unequalled way of providing ideal food for the healthy growth and development of infants. As per the national family health survey-3 (NFHS-3), only 46% of the Indian infants between 0 and 6 months are exclusively breastfed. Hence the following study was done to know the practice of breastfeeding in mothers of rural and urban areas of India. Method- The study was carried out in a rural …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 01–08 Read article
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Molecular Docking and Pharmacokinetic Profiling of the Phytocompounds of Jatropha curcas as Antagonist for Salmonella typhi
Abstract: Background: Typhoid is an infection caused by the Gram-negative bacterium, Salmonella enterica serovar typhi. The study assessed the potential use of Jatropha curcas as a typhoid fever therapy alternative to traditional medications. The ability to uncover novel drug indications for currently available medications using in silico methods has increased thanks to the wealth of pharmacological and biological knowledge that is available. Objective: In this study, we assessed the potential inhibitory …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 67–81 Read article
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Malicious Application Detection in Windows Using SVM Algorithm
Abstract: In recent years, both the development of Windows application clients and the uses of smart mobile phones have increased significantly. As the number of Windows application users continues to grow, there is a rise in malicious individuals who develop harmful Windows applications with the intent of unlawfully obtaining confidential information and engaging in fraudulent activities. These applications are designed to target vulnerable areas such as mobile banking and digital wallets, …
Published in International Journal of Mobile Computing Technology · Vol. 1, Issue 1, 2023 · pp. 30–36 Read article
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A Study on Cancer Related Fatigue and Quality of Life (QOL) among Women Undergoing Treatment for Various Cancers in Selected Tertiary Care Hospitals of Ludhiana, Punjab
Abstract: Cancer is a collection of illnesses marked by irregular cell proliferation that has the potential to infiltrate or metastasize to different areas of the body. Gynecological cancer specifically refers to the abnormal cell growth in the female reproductive tract, including various organs such as the endometrium, fallopian tubes, ovaries, uterus, cervix, vagina, and breast. These cancer cells have a tendency to multiply uncontrollably. The majority of individuals diagnosed with cancer …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 6–11 Read article
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Identification of Secondary Metabolites from Zingiber officinale as Inhibitors for Keap 1-Nrf2 small Molecules through Molecular Docking Techniques
Abstract: Objective: Therapeutic plants aid in treating cancer-based cell signaling pathways and preventing certain risk factors. Zingiber officinale has a variety of anti-inflammatory characteristics also contributing to enhanced immunity, reducing cancer risk and used to target the KEAP NRF2. When overexpressed in response to oxidative stress and DNA damage, elevates the risk of developing multiple cancers. NRF2 cellular sensors, which also control and coordinate their expression aid in defending healthy cells …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 35–48 Read article
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Stress Level and Coping Strategies Among the Students Preparing for Common Entrance Test in Coaching Classes of a Selected City
Abstract: Stress is a natural response of your body to any type of demand, whether it is a positive or negative experience. When individuals experience stress due to external factors, their bodies release chemicals into the bloodstream, which can be beneficial if the stress is caused by physical danger. However, if the stress is a result of an emotional situation and there is no way to channel this additional energy and …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 13–21 Read article
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Innovative 3D Printed Cell Scaffolds with Magnetized Nanocomposites for Targeted Cancer Therapy Drug Delivery
Abstract: In recent years, scaffolds have gained increasing attention in the field of tissue engineering, especially in cancer treatment. Nanocomposite scaffolds have emerged as promising candidates for delivering drugs to cancer cells. 3D printing technology has enabled the fabrication of customized scaffolds with precise pore size and complex geometries. This study explores the development of 3D printed scaffolds of nanostructured made of graphene oxide and Poly-Caprolactone (PCL) nanocomposites, which can be …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 48–55 Read article
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In Silico Docking Analysis to Identify Therapeutic Benzoic Acid Derivatives for Acute Myeloid Leukaemia
Abstract: Background: The study is anchored to initiate subjugation against modern cancer therapy for Acute Myeloid Leukaemia (AML) which involves natural therapeutics as an alternative therapy that would degrade the prospect of adverse side effects along with anti-cancer properties. Objectives: Collate the various characteristics of Giltertinib with natural benzoic acid derivative phytochemicals for a disquisition regarding their similarities and differences in the context of providing adverse side effects. Methods: ADME toxicity …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 50–63 Read article
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Drugs for Alzheimer’s Disease from Salix Alba Discovered Computationally Utilizing Virtual Screening and Docking against 1b41 Protein
Abstract: Objective : The of this research is to evaluate the feasibility of using molecular docking techniques to identify novel acetylcholinesterase, a key enzyme implicated in the pathogenesis of Alzheimer’s disease, a neurodegenerative disorder with a gradual but steady progression to death, due to the gradual accumulation of beta-plaques and neurofibrillary tangles, as well as a decline in acetylcholine levels. Due to its function in converting acetylcholine into acyl and choline …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 07–19 Read article
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A Security Investigation Survey of Ransomware Detection and Avoidance Strategies for IoT Networks
Abstract: The internet of things (IoT) refers to the interconnection of a large number of distinct physical objects, which in turn makes possible a variety of services and applications. Because the IoT sector is developing at such a rapid rate, ensuring its safety ought to be a high concern. At this time, ransomware attacks constitute the biggest danger to IoT posed by cyberattacks. Ransomware is software that blocks access to or …
Published in International Journal of Information Security Engineering · Vol. 1, Issue 2, 2023 · pp. 14–23 Read article
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Numerical Analysis of Battery Thermal Management Using Phase Change Material Concerning Melting Fraction and Temperature
Abstract: This work, analysis and simulates a phase change material melting for battery thermal management (BTM). Phase change materials (PCM) are the substances that, undergo through a phase transition, such as melting from solid to liquid by absorbing or releasing a significant amount of energy as heat. PCM is advantageous for the thermal control of batteries because of this characteristic. As the battery produces heat, the PCM surrounding it absorbs the …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 19–31 Read article
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Topology Optimization of Press Tools for Additive Manufacturing: Reducing Manufacturing Time
Abstract: This research paper presents a topology optimization study of a press tool consisting of a punch and a die, with the aim of optimizing the press tool topology to reduce material usage, and manufacturing time while maintaining necessary strength. The tools will be manufactured using additive manufacturing technology with Polylactic Acid (PLA) material. The Additive Manufacturing method can be used to make prototypes of press tools in the development stages. …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 40–56 Read article
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A Critical Review on Semi-solid and Solid Lubricants for Industrial Applications
Abstract: Friction materials are very important for the safe moving of automobiles and the safety of people. As the pad slides against its match, the moving energy is turned into heat by the friction. As the vehicle's speed is lost as heat in the pads and rotors, the friction at the contact slows it down. Lubricants are compounds that are applied to moving parts to reduce friction and wear. Used primarily …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 105–114 Read article
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Inhibition of PI3K/Akt/mTOR Signaling Pathway by Vitis Vinifera Phytocompounds: A Promising Strategy for Supressing Colorectal Cancer Growth and Metastasis
Abstract: Objectives: Colorectal cancer was not typically identified a few decades ago. Today, with almost 900 000 fatalities each year, it is the fourth most dangerous cancer in the world. Colorectal cancer is responsible for about 10% of all cancer diagnoses annually and cancer-related deaths worldwide. It is the second most common type of cancer in women and the third most common type in men. Incidence and death are roughly 25% …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 64–75 Read article
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Energy Savings due to passive strategies in contemporary high-rise residential building hot and dry climate
Abstract: Globally, the development of sustainable design techniques is becoming imperative, particularly with the idea of high-rise structures to keep up with the rapidly expanding cities. Approaching design sustainably by developing various sustainable methods is becoming necessary worldwide. Strategies for passive design may be useful in achieving the social, economic, and environmental goals of sustainability. This paper discusses the importance of passive design strategies in high-rise buildings, particularly in the context …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 2, 2023 · pp. 99–103 Read article
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Smart Shuttle System: An IoT and Machine Learning Based Approach
Abstract: The Smart Shuttle System is an IoT-based system designed to provide a hassle-free, cashless payment experience for students using the shuttle service. The system utilizes RFID (Radio Frequency Identification) technology to identify students and deduct the fare amount from their account. Radio Frequency Identification (RFID) technology is being considered as an alternative to traditional money and Unified Payments Interface (UPI) for making payments due to several advantages it provides over …
Published in International Journal of Satellite Remote Sensing · Vol. 1, Issue 1, 2023 · pp. 9–22 Read article
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Experimental Investigation of Aerodynamic Characteristics of Dimpled 3D Aircraft Wing
Abstract: There is a strong demand for innovative designs, optimization of the aircraft components for their parts with respect to design, etc. One such innovation is by introduction of dimples in the wing of the aircraft. To study the effect of geometry modification of the wing, the present work compares the aerodynamic efficiency, ratio of lift to drag coefficients, along with different aerodynamic characteristics of an Inward and outward circular dimpled …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 1, Issue 1, 2023 · pp. 11–22 Read article
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AI-driven Flood Surveillance and Dam Control: Advancing Resilience Through Data Science
Abstract: This study presents the development and real-world deployment of an intelligent system for flood monitoring and automated dam gate control using artificial intelligence (AI) and internet of things (IoT) sensors. Supervised machine learning models are developed to predict floods up to 48 h in advance. An automated dam gate operation system is designed to leverage the flood forecasts and real-time stream water levels for emergency control. The complete end-to-end infrastructure …
Published in International Journal of Data Structure Studies · Vol. 1, Issue 2, 2023 · pp. 9–17 Read article
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Study The Effect of Metakaolin Powder in Hot Mix Asphalt as Mineral Filler
Abstract: Mineral fillers are crucial for bridging the spaces between the internal particles of the asphalt matrix. The purpose of this study is to investigate the mechanical properties of hot mix asphalt as well as the impact of utilising Metakaolin (MK) as a mineral filler. Coarse aggregate, fine aggregate, and filler are the main components of hot mix asphalt (HM). With or without modifiers, materials and asphalt binders. HMA components have …
Published in Journal of Polymer & Composites · Vol. 11, Issue 10, 2023 · pp. 9–15 Read article