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274 articles for “Morbidity”
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Case Report: A Rare Case of Dermatofibrosarcoma Protuberans
Abstract: Dermatofibrosarcoma protuberans (DFSP) DFSP is a low grade cutaneous malignancy first described in 1890 by Taylor. Darierwas credited with establishing DFSP as a clinicopathologic entity in 1924 and HOFFMAN established the term in 1925.Clinical diagnosis requires a high index of suspicion because the lesion often has a fairly innocuous gross appearance. After biopsy or excision, expert pathological assessment with focused immunohistochemistry testing is essential to differentiate DFSP with other superficial …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 6, Issue 1, 2017 · pp. 17–23 Read article
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Human Arginase I (Arg I)—A Potential Broad-spectrum Anti-cancer Agent: Perspectives and the Road Ahead
Abstract: Cancer is the second leading cause of morbidity and mortality globally. A variety of effective regimens are available for the treatment of different cancers, however, there is still a need for the development of safe and effective broad-spectrum anti-cancer agent(s). Towards this, amino acid-depleting enzymes have proven to be effective in the treatment of certain auxotrophic cancers. In this review, we have briefly discussed arginine metabolism and arginine depletion as …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 3, 2020 · pp. 23–35 Read article
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Role of a Clinical Pharmacist in Attaining Medication Adherence in Oncology Department
Abstract: A Clinical pharmacist aims to contribute to safe medication use by providing comprehensive management to patients and medical staff, both in the community and the hospital. In oncology, these services include comprehensive medication reviews integrating chemotherapy, supportive care and treatment for co-morbidities, medication information for the medical staff and patients, therapeutic drug monitoring anticancer agents, supportive care counseling (nutritional support, pain management, chemotherapy side-effects prophylaxis and treatment), elaboration of therapeutic …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 10, Issue 3, 2021 · pp. 35–49 Read article
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Recurrent Pregnancy Loss and Thrombophilia: An insight
Abstract: By definition, thrombophilia refers to acquired and/or hereditary diseases that predispose people to venous and arterial thromboembolic events. The most common cause of death on the planet is thrombosis. Myocardial infarction and stroke are major causes of morbidity and mortality in the vascular system. The deep veins of the lower extremity are the most usually involved in venous thromboembolic events, which can lead to pulmonary emboli. Thromboembolism is the major …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 2, 2022 · pp. 1–7 Read article
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Role of USG Guided Percutaneous Needle Aspiration in Pyogenic Liver Abscess
Abstract: Background: Liver abscess has been a condition of high mortality and morbidity in past but since there is work done over decades with use of percutaneous aspiration and percutaneous drainage along with antibiotics; percutaneous drainage is currently the treatment of choice in liver abscess. Percutaneous needle aspiration (PNA) as an alternative to continuous percutaneous catheter drainage in combination with systemic antibiotics for the treatment of PLA has never been popular.Aims …
Published in Research and Reviews : Journal of Surgery · Vol. 6, Issue 2, 2017 · pp. 22–27 Read article
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Prediction of Resectability and Surgical Outcome of Periampullary Tumors
Abstract: Background: Pancreatic cancer is a devastating malignancy with nearly as many deaths as newly diagnosed cases each year with 5-years overall survival rate approximately 7%. Our aim was to assess prediction of respectability of patients with periampullary tumors to avoid unnecessary laparotomy in inoperable patients and evaluation of early outcome of surgical intervention. Methods: 23 patients were included in this study. All the patients were subjected to assessment by contrast …
Published in Research and Reviews : Journal of Surgery · Vol. 7, Issue 1, 2018 · pp. 14–21 Read article
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Post-operative Wound Sepsis and Prophylactic Antibiotic
Abstract: Background and Objectives: Post-operative wound sepsis has been an area of prime interest as tackling it has been a surgeon’s primary role. They have been treating patients in sepsis and preventing sepsis in their operative work. With the advent of modern antibiotics, rate of incidence hasreceded. Timing of antibiotic administration is critical to efficacy. The aim of this study is to evaluate the incidence of post-operative wound infection in A.J. …
Published in Research and Reviews : Journal of Surgery · Vol. 7, Issue 3, 2018 · pp. 9–15 Read article
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Study of Blunt Traumatic Abdominal Solid Organ Injuries with Special Reference to Non-operative Management
Abstract: With increasing number of motor vehicles, the incidence of Blunt Trauma Abdomen (BTA) is on the rise. It has been posing severe threat to mobile population of society. With paucity of specialized trauma centers at primary and secondary level hospitals, BTA is either missed or delayed or is over enthusiastically treated by operative intervention in all cases, thereby increasing morbidity and mortality. The aim is to evaluate the criteria for …
Published in Research and Reviews : Journal of Surgery · Vol. 3, Issue 1, 2014 · pp. 26–29 Read article
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Study of Leucocyte Count, Serum Bilirubin and C-Reactive Protein Values in Preoperative Diagnosis of Acute Appendicitis
Abstract: Acute appendicitis is one of the most common surgical emergencies all over the world. In appendicular perforation, morbidity and mortality increases significantly. A prompt diagnosis and early surgery can only be done if clinical findings are supported by laboratory tests. To estimate preoperative serum leukocyte count, total bilirubin and C-reactive protein levels in patients with clinical diagnosis of acute appendicitis and compare them with histopathological diagnosis postoperatively. Cross sectional study …
Published in Research and Reviews : Journal of Surgery · Vol. 4, Issue 1, 2015 · pp. 20–26 Read article
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Comparative Study of Open and Closed Method for Treatment of Pilonidal Sinus
Abstract: The aim of this study was the comparison between primary closure and open technique after excision of pilonidal sinus. Group A-10 patients treated by open method (excision followed by healing by secondary intention) and group-B 10 patients treated after excision PNS primary midline suturing done with according to the inclusion and exclusion criteria of study. Assessment of operation time and postoperative assessment of pain, hospital stay, time taken to return …
Published in Research and Reviews : Journal of Surgery · Vol. 4, Issue 3, 2015 · pp. 4–7 Read article
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Patterns and Risk Factors of Gestational Diabetes Mellitus among Mothers Who Visited Antenatal Clinics in Public Health Centers of Mekelle City, Tigray, Ethiopia, 2015
Abstract: Gestational diabetes mellitus is associated with significant morbidity in the short and long-term, for both mother and offspring. It is now well established that women with a history of GDM are at a significant increased risk of developing type-2 diabetes, later in life. There were limited studies conducted on pattern and risk factors of gestational diabetes mellitus in Tigray region. The aim of this study is to assess patterns and …
Published in Research and Reviews : Journal of Surgery · Vol. 5, Issue 2, 2016 · pp. 12–20 Read article
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Sociodemographic Determinants of Tobacco Use among Patients Admitted in a Tertiary Care Hospital
Abstract: Tobacco use is the most important contributor to morbidity and premature death among modifiable lifestyle factors. More than five million of those deaths are the result of direct tobacco use while more than 600 000 are the result of nonsmokers being exposed to second-hand smoke and the annual death toll could rise to more than eight million by 2030. A cross-sectional survey was conducted where males and females of 18–65 …
Published in Research and Reviews : Journal of Surgery · Vol. 5, Issue 3, 2016 · pp. 29–34 Read article
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Breast Cancer at Community Level in Bangladesh
Abstract: Background: Breast cancer is an issue of gaining concern in Bangladesh that causes high mortality and morbidity. Lack of screening and surveillance programme contributes to this. Almost no baseline data were found in this issue, though Government of Bangladesh launched a breast cancer surveillance programme based on clinical breast examination (CBE). This research was an effort to produce some baseline data to strengthen the programme of Government of Bangladesh. Methods: …
Published in Research and Reviews : Journal of Surgery · Vol. 8, Issue 2, 2019 · pp. 4–7 Read article
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Initial Diversion in Hirschsprung’s Disease: Loop versus End Colostomy. Does it Make a Difference?
Abstract: Background: Staged surgery for Hirschsprung’s disease involving initial stoma formation with biopsies to find the level of aganglionosis and subsequent pull-through procedure like Duhamel’s Pull through is the most recommended management protocol at several institutions. The nature of stoma, whether loop or end, often determines the patient’s morbidity in this approach and would also have a say in the duration and ease at the time of definitive pull-through procedure. Aims …
Published in Research and Reviews : Journal of Surgery · Vol. 8, Issue 3, 2019 · pp. 4–8 Read article
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Carotid Blowout Syndrome after Neck Dissection: How Far We Know?
Abstract: Carotid blowout syndrome (CBS) is one of the most dreaded complications of neck dissection. CBS was once shown to have a high morbidity and mortality rates in all of its three types; however, with recent advancement in the medical field these rates decreased considerably. Surgeons and medical practitioners must have a thorough knowledge about this serious condition and the different ways of managing it. This paper is an overview of …
Published in Research and Reviews : Journal of Surgery · Vol. 8, Issue 3, 2019 · pp. 14–22 Read article
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Thyroid Abscess: Presentation and Management: A Case Report in Adult Patient
Abstract: Introduction: Thyroid abscess is an uncommon condition. This is due to: 1) anatomical factors in the form of rich blood supply and well developed capsule; and 2) physiological factors such as high iodine content. Both Acute Suppurative Thyroiditis (AST) and thyroid abscess represent 0.1 to 0.7% of the thyroid lesions managed surgically. Aim: To raise the clinical suspicion of this condition among clinicians so that it can be diagnosed early …
Published in Research and Reviews : Journal of Surgery · Vol. 9, Issue 3, 2020 · pp. 8–12 Read article
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Microsurgical Neurolysis, Dorsal Transposition and Nerve Wrap of Morton’s Interdigital Neuroma: A Novel Technique
Abstract: The treatment of Morton’s neuroma is varied with multiple options, both surgical and non-surgical. However, surgical treatment is indicated for persistent, severe, and recurrent forefoot pain whereby conservative measures have failed. The choice of surgical technique is controversial and depends on the patient presentation and surgeon preference. The key mantras in the successful treatment of this challenging condition are thorough clinical evaluation, proper patient selection, preoperative counselling, and meticulous surgical …
Published in Research and Reviews : Journal of Surgery · Vol. 10, Issue 1, 2021 · pp. 24–31 Read article
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Some Neurofasciocutaneous Flaps in the Coverage of Lower Leg Soft Tissue Defects
Abstract: Reconstruction of soft tissue defects of heel, ankle, and distal third of the leg is one of the most difficult assignments for plastic surgeons and it remains a challenge to seek safer options with less morbidity. We report on 28 pedicle perforator flaps without harvesting major vessels in the lower leg reconstruction. In the lower extremities, there were 16 sural neurofasciocutaneous flaps with an axis on the sural nerve, 8 …
Published in Research and Reviews : Journal of Surgery · Vol. 11, Issue 1, 2022 · pp. 7–12 Read article
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An Outline of Poisoning at Kadapa (South India)
Abstract: The epidemiology of poisoning can be studied from different perspectives. Early correct diagnosis and appropriate treatment, conversely, are often lives saving. Therefore, the knowledge of the general pattern of poisoning in a particular region would help in early diagnosis and management of poisoning, which in turn should result in a reduction of morbidity and mortality. Retrospective observational Study was conducted for a period of six months in the general medicine …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 2, 2014 · pp. 5–7 Read article
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Research and Review: On Irsale Alaq (Medicinal Leech), Mechanism of Action and its Uses with Applied Site
Abstract: Leech therapy is based on the concept of balancing body humours. In the Unani system of medicine the majority of the disease caused by the endogenous factors by excessive Humours accumulated of morbid matters foodstuffs or the metabolic products. There are 6 evacuation methods for the balancing of humours viz bloodletting, purging, vomiting, sweating, cauterization and diuresis are described. Among those methods, bloodletting methods are a most popular and effective …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 6, Issue 1, 2019 · pp. 19–25 Read article