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235 articles for “Bioactive compound”
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Enhancement of Some Pharmaceutically Important Secondary Metabolites By in vitro Techniques
Abstract: AbstractSecondary metabolites are economically important as drugs, dyes and pigments, pesticides, and food additives. The evolving commercial importance of secondary metabolites has in recent years resulted in a great interest in mechanism of secondary metabolism, especially in the production of bioactive plant metabolites by means of tissue culture technology. Plant cell and tissue culture technologies can be established for both multiplication and extraction of secondary metabolites. Strain improvement, methods for …
Published in Research & Reviews : Journal of Herbal Science · Vol. 3, Issue 1, 2014 · pp. 6–14 Read article
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Plant-Derived Antimicrobials as Next-Generation Solutions to Multidrug Resistance
Abstract: The steady rise of multidrug-resistant (MDR) pathogens is reshaping how clinicians, researchers, and policymakers think about infection control. When bacteria acquire the ability to survive exposure to three or more antibiotic classes at once—whether through efflux pumps, enzyme-mediated drug destruction, target modifications, or reduced membrane permeability—treatment options narrow dramatically, hospital stays lengthen, and mortality climbs. Conventional pharmaceutical pipelines have struggled to keep pace with this biological arms race, pushing the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 · pp. 27–40 Read article
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Phyto-Entrapped Carbon Dots as Emerging Nanomaterials for Anti-Cancer Activity
Abstract: Phytoconstituent-loaded carbon dots (C-dots) represent an innovative approach in targeted cancer therapy, combining the therapeutic power of plant-derived compounds with the advanced capabilities of nanotechnology. These ultra-small, biocompatible nanostructures offer excellent fluorescence, tunable surface chemistry, and low toxicity, making them ideal for drug delivery, bioimaging, and theranostic applications. Traditional phytochemicals often face challenges like poor solubility, low bioavailability, and high first-pass metabolism barriers that C-dots help overcome. C-dots synthesized through …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 51–63 Read article
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Pharmacognostical and Pharmacological Review of Urtica dioica L.
Abstract: Urtica dioica (stinging nettle) belonging to family Urticaceae, is obtained from word ‘uro’ to burn or ‘urere’ denotation to sting. It is found in the Himalayas region from Kashmir to Kumaon region (Uttarakhand.). The plant has been used in traditional system of medicines especially uses nasal and menstrual haemorrhage, eczema, rheumatism, nephritis, anaemia, diarrhoea, jaundice and epilepsy. The plant contains bioactive constituents like tannins, fatty acids, flavonoids, sterols, isolectins, proteins, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 6, Issue 2, 2019 · pp. 23–29 Read article
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Chemical Composition and Antimicrobial Efficacy of Ferula persica Extracts: A Phytochemical and Bioactivity Assessment in Iraq
Abstract: The research presented in the tables focuses on analyzing the chemical content of extracts from the Ferula persica plant, a wild species in Iraq with significant medical and therapeutic importance dating back to ancient times. This study involved testing some chemical and physical properties of the alcoholic extract of the plant's aerial parts and evaluating its antimicrobial activity, specifically against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). The …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 10–22 Read article
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Polymer Chemistry in Nutraceutical Composites: Exploring Natural Polymers and Binding Systems in a Bamboo-Enhanced Formulation
Abstract: Polymer chemistry underpins the development of advanced nutraceutical composites, blending natural polymers with functional ingredients for health benefits. This study examines a novel nutraceutical formulation comprising ragi (16.39 g/100g), wheat (12.29 g/100g), soybean (12.29 g/100g), buffalo milk (16.39 g/100g), buffalo butter (4.13 g/100g), bamboo extract (0.90 g/100g), and auxiliary components (37.61 g/100g, including fats, sugars, and proteins). Natural polymers—proteins from soybean and milk, polysaccharides from ragi and wheat—form a macromolecular …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 878–884 Read article
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Casein - A Unique Milk Protein
Abstract: Milk is a nutrient-rich food that contains proteins, fats, lactose, vitamins, minerals, enzymes, and other organic compounds. Essential for young mammals, milk proteins provide amino acids, nitrogen, and minerals necessary for muscle and tissue development. In human nutrition, milk is valued for its digestibility and as a source of calcium and phosphorus, crucial for infant growth. Milk proteins are classified into two primary types: caseins, which make up 75–80% of …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 3, 2024 · pp. 27–34 Read article
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Phytochemical Screening and Structural Elucidation of Extracts from Garcinia kola (Heckel) Seeds
Abstract: This study evaluated the bioactive components of G. kola seeds extract to further establish its medicinal potentials. Extracts were obtained using different solvents thus; ethanol, methanol, ethyl acetate, acetone, cold and hot water. Phytochemical (quantitative) screening showed that saponins, flavonoids, terpenoids, tanins, glycoside and alkaloids are present in the G. kola extracts: however, the quantities vary with regards to the extraction solvent used. The highest quantity of phenols (35.63±0.06 mg/g) …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 7, Issue 2, 2020 · pp. 23–27 Read article
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Ethnobotanical, Phytochemical, and Pharmacological Aspects of Piper nigrum (Filfil siyah): An Update
Abstract: Piper nigrum (Filfil siyah) is a very popular medicinal plant. It is used in Unani as well as the Ayurvedic System of medicine for several diseases due to their diverse pharmacological potentials and minor side effects. In the Unani System of Medicine, it is recommended for the treatment of Nafkh al-Mi‘da (Flatulence in the stomach), Qulanj Rihi (colic due to flatulence), Waj-ul-Meda (Gastric Pain), Kasir-e-Riyah (Carminative), Zofe-Ishtiha (Anorexia), Muharrik (Stimulant), …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 11, Issue 3, 2022 · pp. 26–35 Read article
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High Performance Liquid Chromatographic Analysis and Antibacterial Activity of Methanolic Seed Extract of Syzygium cumini L.
Abstract: Syzygium cumini is a medicinally important plant widely used in traditional systems of medicines specifically Ayurveda followed in India. The seeds of the plant are recognized in various bio medicines for the treatment of diabetes. It is reasonable source of natural antioxidants used in dietary supplement of food and bioactive substances in cosmetics and pharmaceutical industries. In the present study, Syzygium cumini (jamun) seeds were collected from the Alagar Kovil …
Published in Research & Reviews : Journal of Herbal Science · Vol. 11, Issue 2, 2022 · pp. 23–30 Read article
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Molecular Docking and Interaction of Anthocyanin Derivatives in Regulating Hippo-taz Pathway for Renal Injuries
Abstract: Introduction: The Hippo pathway plays a pivotal role in renal disease, with Yes-associated protein (YAP) exhibiting promise for combined treatments. The crucial evaluation of YAP-targeted drug safety and efficacy through preclinical studies is imperative. Additionally, α-SMA and SMAD3 emerge as potential therapeutic targets in renal fibrosis, driving ongoing research toward innovative interventions. Materials and Methods: In the systematic identification of therapeutic secondary metabolites, Anthocyanin derivatives were methodically retrieved from the …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 23–38 Read article
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Clinical Applications and Mechanism of Leech Therapy from the Perspective of Unani and Conventional Medicine: A Review
Abstract: Leech therapy is a kind of bloodletting that involves using leeches to remove a significant volume of blood from the body. Leeches are hermaphrodites, annelid worms that feed on blood and have a noticeable capacity to expand or contract. Hirudinaria granulosa is a type of Indian leech that has therapeutic qualities. Leech therapy operates on the tenets of Imala-i-Mawād (Diversion of morbid matter) and Tanqiya-e- Mawād (Evacuation of Morbid matter). …
Published in Research & Reviews : Journal of Herbal Science · Vol. 12, Issue 3, 2023 · pp. 7–12 Read article
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Phytochemicals And Antioxidants Properties of Zanthoxylum zanthoxyloides Root Bark
Abstract: There have been studies on Zanthoxylum zanthoxyloides (Orinata), family; Rutaceae, which has shown remarkable benefits of the plant to humans traditional medicine. Root or stem bark macerations, decoctions or infusions of the plant are widely taken to treat malaria, fever, sickle cell anemia, tuberculosis, paralysis, oedema and general body weakness. They are also widely taken to treat intestinal problems, including colic, dysentery, intestinal worms, gonorrhea and urethritis. Studies show that …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 13, Issue 2, 2022 · pp. 23–28 Read article
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Nanostructured TiO2 Prepared Through Sol–Gel Method Enhances the Activity of Antibiotics against Gram Positive Bacteria
Abstract: The synthesis and bioactivity of titanium dioxide (TiO2) nanoparticles has been extensively studied. However, the antibacterial activity of TiO2 individually or in combination with different antibiotics has not been demonstrated. TiO2 was prepared by sol–gel process using precursor Titanium (IV) Chloride (TiCl4) and concentrated sulfuric acid in 4 h of calcinations at 550 °C and the enhancement effect of TiO2 nanoparticle on the antibacterial activity of different antibiotics was evaluated …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 2, Issue 1, 2012 · pp. 6–12 Read article
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Modulation of Receptor Proteins: A Recent Paradigm in Drug Discovery and Target
Abstract: The main aim in drug discovery is to design different ligands those work on specific drug targets. However, various effective drugs work through the modulation of many proteins than single target. Advancement in system biology are establishing a phenotypic strength and a network structure, which suggests that, the excellent selective compounds may be performed less than desired clinical efficacy in comparison to multi-target drugs. In this new appreciation of the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 14–24 Read article