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285 articles for “AI agents”
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An Update on HIV-2 Infection
Abstract: Human immunodeficiency virus type 2 (HIV–2) infection is an important cause of disease in a number of regions of the world. But the knowledge about this infection is sparse. Prevalence data on HIV-2 is heterogeneous. HIV-2 has a lower infectivity than HIV-1 which can be related to the lower RNA levels in this virus. The rate of progression to Acquired Immunodeficiency Syndrome (AIDS) in HIV-2-infected patients is highly variable making …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 2, 2018 · pp. 34–42 Read article
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Modulation of Receptor Proteins: A Recent Paradigm in Drug Discovery and Target
Abstract: The main aim in drug discovery is to design different ligands those work on specific drug targets. However, various effective drugs work through the modulation of many proteins than single target. Advancement in system biology are establishing a phenotypic strength and a network structure, which suggests that, the excellent selective compounds may be performed less than desired clinical efficacy in comparison to multi-target drugs. In this new appreciation of the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 14–24 Read article
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Exploring Emerging Water Disinfection Technologies: A focus on Hydrodynamic Cavitation
Abstract: Availability of clean drinking water is an ongoing global demand. Contaminated water sources, inappropriate waste disposal, and inadequate hygiene procedures exacerbate it. These elements support the growth of pathogenic microbes like bacteria, viruses, and parasites, which cause a variety of diseases that are transmitted by water. Disinfection plays a vital role in water treatment processes by eliminating these pathogens and ensuring public health safety. Commonly used methods like Chlorination, Ozonation, …
Published in Journal of Water Pollution & Purification Research · Vol. 11, Issue 1, 2024 · pp. 44–53 Read article
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Anticancer and Antioxidant Property of Bunium bulbocastanum Fruits Various Fractions
Abstract: Bunium bulbocastanum (family Apiaceae) fruits are normally used as a culinary spice for years. Since antioxidant property has a significant role in preventing oxidative stress, which has been demonstrated to be a major cause in the pathogenesis of cancer, the present study was aimed to evaluate the in vitro antioxidant and cytotoxic effect of Bunium bulbocastanum fruit extracts. Standard in vitro antioxidant assays such as reducing power, super oxide scavenging, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 3, Issue 1, 2016 · pp. 9–13 Read article
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Synthesis of Silver Nanoparticles of Cissus Quandrangularis and It’s Virtual Screening Against Gastric Cancer
Abstract: Gastric cancer, also known as stomach cancer, is the third leading cause of cancer-related deaths globally and remains a major health challenge due to its poor prognosis and high mortality, largely attributed to late-stage diagnosis. In this context, plant-based nanomaterials are gaining momentum for targeted therapeutic applications. Cissus quadrangularis, a medicinal plant native to India from the Vitaceae family, is traditionally used for its diverse healing properties. Its stem, in …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1551–1569 Read article
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Herbal Immuno-modulators- Pros and Cons
Abstract: Recently, there has been a greater global focus on plant research, and a ton of data has accumulated to show the enormous potential of the medicinal plants used in various traditional systems. In actual practise, the majority of immunostimulants and immunosuppressants are cytotoxic medications with substantial side effects. In treating immune-related disorders, there is growing interest in using herbal medicines as multi-component agents to modulate the complex immune system and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 10, Issue 3, 2023 · pp. 22–29 Read article
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An Overview Of Phytochemical Constituent Identification Test And Therapeutic Actions Of Tribulus Terrestris Linn. Plant
Abstract: Tribulus terrestris is a plant often promoted as a dietary supplement for various health benefits, including increased testosterone levels. Some studies suggest potential positive effects on sexual function, but overall, more research is needed. Individual experiences with supplements can vary, so it's advisable to consult with a healthcare professional before using them. Tribulus Terrestris Linn. is a yearly growing herb which is found actually in china ,japan, western Asian countries, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 10, Issue 3, 2023 · pp. 41–49 Read article
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Effect of Sodium Fluoride and Cellulose Gum Toothpaste over Regular SLA Toothpaste in Reducing Xerostomia-A Retrospective Cohort Study
Abstract: Our aim is to study the effect of mildly flavoured sodium fluoride 0.2% and cellulose gum on patient suffering from chronic xerostomia in comparison to effect of general sodium Laurel sulphate containing toothpaste on same condition patient. A controlled study population was used for the investigation. The baseline for this study is to estimate the risk of developing xerostomia or worsening of the condition in patient already suffering from xerostomia …
Published in Research and Reviews: A Journal of Dentistry · Vol. 13, Issue 2, 2022 · pp. 22–24 Read article
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Current Issues in Understanding of Diabetes
Abstract: Diabetes mellitus is a significant metabolic disorder that poses a major health concern, particularly in India. India harbours the world's highest number of diabetic patients, totalling around 130 million, with an additional 40 million categorised as prediabetic. In the global context, the number of adults suffering from diabetes was roughly 150 million in 2000, but this number is projected to significantly increase by 2030. The global prevalence of prediabetes is …
Published in Research and Reviews: A Journal of Medicine · Vol. 13, Issue 2, 2023 · pp. 1–12 Read article
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Over the Counter Drugs Use by Libyan Women before and during Pregnancy
Abstract: Information on the safety of drugs is particularly important during pregnancy because pregnant women may have chronic diseases requiring medical intervention, for example, epilepsy, diabetic mellitus, or asthma. Alternatively, they develop pregnancy-induced problems such as hypertension or diabetes. For both situations, drug use in pregnancy is necessary. To avoid all drugs in pregnancy is unreasonable and may be dangerous. The main aim of this study was to measure the frequency …
Published in Trends in Drug Delivery · Vol. 8, Issue 1, 2023 · pp. 14–21 Read article
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Protein Modeling and Drug Docking Studies on Potential Protein Target (E. coli–dosP) and Compound Aldehyde (Sumatriptan) using Bioinformatics Tools
Abstract: The aim of the present in silico studies is to find out the potential protein target in stationary phase-induced biofilm regulator (E. coli–dosP) and deliver the 3D structure and to introduce the best inhibitors of aldehydes (Sumatriptan) using molecular drug docking techniques. The potential chemical compound, Aldehyde (Sumatriptan) was retrieved from NCBI PubChem compound database and converted into the 3D structure using online smiles translator and finally docking studies were …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 5, Issue 3, 2018 · pp. 9–18 Read article
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Molecular Characterization of Respiratory Viral Infections and Co-Infections in Pediatric Patients Using FilmArray™ Multiplex PCR in a Tertiary-Care Hospital, South India
Abstract: Respiratory tract infections (RTIs) are a major cause of pediatric morbidity worldwide, with viruses, such as respiratory syncytial virus, rhinovirus/enterovirus, influenza virus, adenovirus, and parainfluenza virus, contribute significantly to hospitalizations. Conventional diagnostic methods often require prolonged processing times, which can delay clinical decision-making. Rapid molecular platforms, such as the FilmArray™ Panels, offer timely and comprehensive pathogen identification. This study aimed to evaluate the prevalence, seasonal trends, and co-infection patterns of …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 2, 2026 · pp. 57–66 Read article
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Treatment of Textile Wastewater using Bentonite Clay as a Natural Coagulant
Abstract: The main objective of the present study was treatment of dye waste by coagulation with clay to achieve maximum removal efficiency of color and sludge.The present study was aimed to investigate the effects of bentonite clay as coagulant in treatment of textile wastewater. The coagulant prepared was employed for the removal of sludge at the different doses. The maximum coagulant for removal of colour and sludge was found at an …
Published in Journal of Water Pollution & Purification Research · Vol. 1, Issue 2, 2014 · pp. 24–27 Read article
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Explanation of Humma Danj (Dengue Fever) in Unani System of Medicine
Abstract: Dengue fever (Humma Danj) is associate acute febrile health problem that caused by flavivirus (animal virus) spread by the genus Aedes mosquito and defined by explosive onset of high-grade fever, severe muscle and joint pain, headache, lymphadenopathy (pathology), etc. Now, no immunizing agents is out there for dengue, and illness management and prevention have within the in the main focused on vector management activities and surveillance that comprises community contribution. …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 9, Issue 1, 2022 · pp. 16–19 Read article
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Natural Cooling Agent: Utilizing Menthol as a Paraben-Free Preservative in Herbal Cosmetics
Abstract: The quest for natural and sustainable alternatives in cosmetic products has intensified, driving the search for effective natural preservatives. Menthol, derived from mint plants, is being recognized for its cooling properties and potential as a paraben-free preservative. This study investigates menthol’s efficacy as a preservative in herbal cosmetics, addressing consumer concerns about synthetic preservatives while ensuring product safety and longevity. This research examines menthol’s antimicrobial effects on common cosmetic contaminants …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 3, 2024 · pp. 16–39 Read article
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A Review Article on Oroxylum indicum: A Versatile Medicinal Tree
Abstract: Oroxylum indicum, commonly known as the Indian trumpet tree or Shyonaka, is a medicinal plant belonging to the Bignoniaceae family. It is widely used in traditional medicine systems such as Ayurveda for treating various ailments including neurodegenerative diseases, cardiovascular conditions, arthritis, hepatitis, malignancies, diarrhea, fever, and jaundice. The plant's therapeutic properties are primarily attributed to its rich content of bioactive flavonoids, which exhibit notable anti-cancer, anti-inflammatory, and analgesic effects. Found …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 2, 2026 · pp. 01–07 Read article
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In Silico Molecular Docking Studies of Phytocompounds from Melissa officinalis Against MPXV Poxin Target
Abstract: Objectives: This study aimed to evaluate the inhibitory potential of phytocompounds of Melissa officinalis against the MPXV poxin protein target, a key virulence factor in monkeypox infection. Methods: Molecular docking performed using PyRx, a virtual screening software, was conducted to predict the binding affinities of the compounds to MPXV poxin. Prior to docking, the compounds were subjected to comprehensive analysis, including Lipinski's rule of five, evaluation of physicochemical properties, pharmacological …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 25–38 Read article
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Exploring Phytochemicals from Ricinus Communis for Potential Therapeutic Applications in Rheumatoid Arthritis: An in-Silico Approach
Abstract: Aim: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by the immune system mistakenly attacking the joints, leading to swelling, discomfort, and joint deformities. Current management strategies include anti-rheumatic drugs and biologics, which have limitations. This study aims to explore the therapeutic potential of Ricinus communis (castor bean plant) phytochemicals as plant-based therapies for autoimmune conditions, like RA. Methods: Phytochemicals from Ricinus communis were retrieved using the IMPPAT database, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 32–41 Read article
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A Clinical Study to Evaluate the Efficacy of Durvadi Taila in the Management of Muladhar Chedan/Yonikshat w.s.r. to Episiotomy Wound
Abstract: Background: Episiotomy is a surgically planned incision on the perineum and the posterior vaginal wall during the second stage of labor. It is more prone to an infection that is why it requires wound care and maintenance. Episiotomy can be compared to Chhina Vrana (a kind of Sadhyo Vrana). Durvadi tail a have been mentioned in Yogratnakar as vrana ropak in the treatment of Sadhyo vrana. Aim: Clinical evaluation of …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 6, Issue 3, 2017 · pp. 8–14 Read article
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In Situ Investigation of Hemidesmus indicus Phytocompound Extracts as a Therapeutic Target for Acute Myeloid Leukemia
Abstract: Objective: Acute myeloid leukemia (AML) is an apoptotic condition in the hematopoietic system induced by the differentiation and maturation of stem cells into erythrocytes, and leukemic cell proliferation is suppressed as the PI3K-Akt-mTOR pathway is pharmacologically targeted with certain inhibitors. As a result, in silico molecular docking of compounds against AML receptors, CTMP, was used in computational research on Hemidesmus indicus to uncover therapeutic phytochemicals for AML. Thus, this study …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 38–53 Read article