Search
336 articles for “genetic study”
-
In Silico Designing of Triazolothiadiazine as Anticancer Agents
Abstract: Cancer is irregular growth of cells and formation of tumor. There are approximately 9.6 million death reported globally. It is caused by physical or genetic factor. There are various targets for the inhibition of growth of cancerous cells. Inhibition of colchicines binding site of tubulin is promising target in field of cancer management. In this study, we designed 25 novel thiazole and triazolothiadiazine derivatives as colchicine binding site inhibitors and …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 6, Issue 1, 2019 · pp. 10–20 Read article
-
Pathogenesis, Immune Response and Vaccine Development in Amoebiasis
Abstract: Worldwide, approximately fifty million cases of invasive E histolytica disease occur each year and resulting in more than 100,000 deaths. It is the second leading cause of mortality due to a protozoan parasitic infection after malaria. Entamoeba histolytica infection is associated with considerable morbidity and mortality in the form of intestinal and extra-intestinal amoebiasis especially in developing countries. Recent molecular studies have conclusively proved that there are morphologically similar species …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 3, 2015 · pp. 30–35 Read article
-
Parametric Optimization of Biocompatible Ti6AL4V Alloy on Selective Laser Melting for Enhanced Structural Support and Reduced Stress Shielding
Abstract: The Selective Laser Melting technique is widely employed in the production of complexly shaped end products for a range of industries, including biomedical, aerospace, automotive, and defence. SLM is a complicated manufacturing process since a lot of factors influence the characteristics of the items that are printed using it. The SLM printing of fully dense parts is becoming more and more popular for various high-end applications. Because of their biocompatibility …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 143–156 Read article
-
Understanding Leukemogenesis: Challenges and Advancements in Diagnostic Approaches
Abstract: Leukaemia development, or leukemogenesis, is a multifactorial process driven by a complex interplay of environmental, genetic, and epigenetic factors. Despite substantial advancements in technology and medicine, which have enhanced our understanding of the contributing factors, early and accurate diagnosis remains a major challenge due to the overlapping clinical features shared by the various leukaemia subtypes. This study explores the molecular and cellular mechanisms underlying leukemogenesis, while also addressing the difficulties …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 11–22 Read article
-
Carrier prospective for Women in Biotechnological Healthcare System
Abstract: In entire world including India, the population of women is nearly equal to male, but in India traditionally women have to carry out well define household work only, but with globalization and government initiative women participation in education has been increased. Now educated women want to compete with men in all fields including various different types of carrier. With time, women participation in the field of genetic engineering and biotechnological …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 3, 2018 · pp. 39s–42s Read article
-
Orthogonal Thirty-Two Phase Sequence Sets Design
Abstract: In using orthogonal signals, a multi-input, multi-output (MIMO) radar system and a spread spectrum communication system can improve operating efficiency. The usage of polyphase coded signals as pulse compression sequences sets is a superior alternative. The Modified Genetic Algorithm (MGA) is utilized as a global optimization strategy to create thirty-two phase sequence sets in this work. Design orthogonal thirty-two phase sequence sets with an impulse-like Autocorrelation Function (ACF) and a …
Published in Current Trends in Signal Processing · Vol. 12, Issue 2, 2022 · pp. 33–39 Read article
-
The Insect Microbiome: Reviewing the Mutualistic Ties Between Insects and Microbes
Abstract: Insects are the most diverse and abundant class of animals on Earth, occupying virtually every terrestrial and freshwater ecological niche. A primary engine driving their evolutionary radiation, nutritional versatility, and physiological resilience is their intimate association with microbial symbionts. The insect microbiome, comprising bacteria, fungi, viruses, and protists, spans a continuum from transient environmental commensals to obligate intracellular mutualists. This review comprehensively synthesizes current knowledge on the functional architecture, transmission …
Published in International Journal of Insects · Vol. 3, Issue 2, 2026 Read article
-
Graph Theory: Its Importance and Application in Recent development of Science and Engineering
Abstract: Graph Theory is widely used in all the basic sciences including social science, due to its intrinsic simplicity it has got a lot of application in computer science, computer networks, engineering, genetics, data structure etc. Graphs are nothing but mathematical structure that helps in representing our everyday problem in a precise graphical manner. Graph Theory is the area of applied mathematics that deals with the study of objects and the …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 10, Issue 3, 2023 · pp. 31–36 Read article
-
Integrating Genetic Algorithms with Lean Manufacturing for Enhanced Production Efficiency
Abstract: Lean manufacturing is a well-established philosophy focusing on the systematic reduction of waste and the ongoing development of value supplied to the customer. It emphasizes efficiency, quality, and adaptability through ideas such as just-in-time production, continuous improvement (Kaizen), and value stream optimization. However, the increased complexity of modern production systems, driven by global rivalry, product variety, and rapid technology innovation, has shown the limitations of classic lean tools in achieving …
Published in Journal of Production Research & Management · Vol. 15, Issue 3, 2025 · pp. 38–43 Read article
-
Management of Duchenne Muscular Dystrophy by Ayurvedic Principles: A Case Study
Abstract: Duchenne muscular dystrophy is the most common and severe form of childhood muscular dystrophy, with an incidence of 1 case in 3500 male births. It is an X linked recessive disorder due to the absence or alteration of the dystrophin protein, encoded by the DMD gene on chromosome Xp21. Corticosteroids are the only medications that have shown to alter the course of DMD but are associated with their side effects …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 1, 2020 · pp. 1–5 Read article
-
Screening of Mustard Varieties and Lines against Clubroot and Alternaria Leaf Spot Diseases
Abstract: The experiment was conducted to find out the resistant varieties/lines against clubroot and Alternaria leaf spot diseases of mustard at the Plant Pathology Division, RARS Jamalpur, Bangladesh during the Rabi season of 2024-2025 with sixty-two (62) varieties and lines of Mustard collected from Oilseed Research Centre (ORC) and Plant Genetic Resources Centre (PGRC), Joydebpur, Gazipur-1701, Bangladesh. To screen for clubroot and Alternaria leaf spot diseases and to evaluate yield and …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 14, Issue 3, 2025 · pp. 97–106 Read article
-
Comparative Proteomics: From Cell Lines to Clinical Samples
Abstract: Comparative proteomics is a powerful tool for understanding the molecular differences between various biological samples. It entails identifying and measuring proteins in complex biological samples to assess their abundance, modifications, and interactions under various conditions. This approach plays a crucial role in advancing biomedical research, especially in disease understanding, biomarker discovery, and therapeutic development. While cell lines are widely used for proteomic studies due to their controlled environments and reproducibility, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 30–34 Read article
-
AI-Driven Multi-Objective Optimization of Conductive Polymer Composites for High-Performance Flexible Electronics
Abstract: The development of conductive polymer composites (CPCs) is critical for advancing flexible and wearable electronic technologies. However, the conventional trial-and-error approach to material formulation is time-consuming and often inefficient due to the high-dimensional nature of the design space. This study introduces a novel AI-driven framework that integrates machine learning (ML) with multi-objective optimization to accelerate the discovery of high-performance CPCs. A dataset of 1,000 experimentally reported formulations was compiled, capturing …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 734–745 Read article
-
Randomized Comparative Clinical Study of Virechana Karma & Dhanyamla Sarvang Dhara in the Management of Sthaulya w. s. r. to Obesity
Abstract: Modernization, affluence, science, and technological development leads to still more sedentary lifestyles, which lead to many disorders in which obesity is considered as a multifactorial disease. The World Health Organization (WHO) recognized obesity as one of the most serious public health problems of the 21st century. Obesity can be defined as abnormal or excessive fat accumulation that presents a risk to health. Obesity is a physiological, psychological, and social disorder, …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 7, Issue 3, 2020 · pp. 40–49 Read article
-
Biological Membranes: Structure, Function, and Their Roles in Disease Pathophysiology
Abstract: Biological membranes are important structures that control cellular work, signal transmission, transport, and communication. Dysfunction of membranes has been considered in the development of many diseases, such as cancer, neurodegenerative diseases, and infections, with the distortion of lipid composition, protein activity, and cellular connections involved in the pathogenesis of the disease. The damage on membrane can be caused by oxidative stress, genetic mutation, and environmental influence to disrupt cellular homeostasis. …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 38–46 Read article
-
Genetic Detection of Hepatitis C -Virus and Occult Hepatitis B in Patients from Al-Najaf Al-Ashraf Governorate, Iraq.
Abstract: Recently, a noticeable increase in the prevalence of occult Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infections has been observed among clinical cases such as patients undergoing hemodialysis, blood transfusion, liver diseases, and thalassemia worldwide. To limit and control this spread, the present study was conducted to investigate and detect the molecular presence of HCV and occult HBV using the Nested PCR technique, as well as to observe …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 1, 2026 Read article
-
Advanced Deep Learning Techniques for Sickle Cell Anaemia Detection
Abstract: Sickle Cell Anemia (SCA) is a prevalent genetic blood disorder characterized by the presence of abnormal hemoglobin, resulting in the distinctive sickle shape of red blood cells. Timely and accurate identification of Sickle Cell Anemia (SCA) is essential for effective management and treatment. This study presents a new method that utilizes Convolutional Neural Networks (CNNs), a deep learning model particularly effective for image analysis. The process involves using microscopic images …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 3, 2024 · pp. 9–15 Read article
-
Significance of TE Domain and Genetic Variations in FASN Gene in Dairy Animals
Abstract: The interest in the bovine fatty acid synthase (FASN) gene has increased during the last few years. FASN is a multifunctional enzyme that catalyzes de novo biosynthesis of long-chain saturated fatty acid, and alteration of this enzyme may affect economic traits including fatty acid composition. FASN is involved in fat metabolism and is an important candidate gene affecting fat composition of milk because of its central role in de-novo lipogenesis …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 6, Issue 3, 2016 · pp. 33–38 Read article
-
Ulcerative Colitis- An Ayurvedic Review And Treatment – A Case Study
Abstract: Ulcerative colitis (UC) is a chronic autoimmune disease that causes inflammation and ulcers of the Large intestine. It is one of the most common GI disorder. Usually the pain affects only the intestinal mucosa and sub mucosa, causing small ulcers in the intestinal lining called ulcers. In most of patients, the disease begins from the anus and continues to spread. Its pathogenesis is multi factorial and includes genetic predisposition, epithelial …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2024 · pp. 31–39 Read article
-
Balancing Welfare-Productivity Trade-Offs: Logical Frameworks and Strategic Approaches for Sustainable Dairy Development
Abstract: Balancing animal welfare and productivity remains a critical challenge in modern dairy farming. This study explores diverse frameworks for evaluating the welfare-productivity trade-offs essential for achieving sustainable dairy systems. Key approaches are categorized into six thematic areas: animal-centric frameworks, management-oriented models, environmental assessments, economic and policy perspectives, technological innovations, and holistic methodologies. Each framework offers unique metrics and evaluation tools, including behavioral assessments, physiological indicators, precision livestock farming, cost-benefit analyses, …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 2, 2025 · pp. 16–24 Read article