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277 articles for “disease mechanism”
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Smart Air Filtration Systems for Cities: A Technological Approach to Reducing Urban Pollution
Abstract: Urban air pollution is considered one of the main ecologically critical issues of the 21st century since it threatens citizens' health through respiratory diseases, pathologies of the cardiovascular system, and even premature death. Regarding an extremely high level of pollution in large cities, it becomes necessary to realize technological solutions which could avoid the negative impact of this phenomenon. Smart air filtration systems have emerged as promising solutions for urban …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 2, Issue 2, 2024 · pp. 27–42 Read article
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Role of Nasya in Pakshaghata: An Evidence-Based Review Study on Its Anatomical Pathway and Therapeutic Action
Abstract: Introduction: Intranasal administration (Nasya), a time-honoured Ayurvedic procedure, offers a unique advantage in treating pathology of neurological and systemic diseases due to its targeted and non-invasive nature. Pakshaghata, a neurological disorder characterized by hemiplegia in ancient Ayurvedic literature, where it is classified as a Vatavyadhi. Methods: By going through all the available literatures and information, this review study explores the concept of Nasya in the context of Pakshaghata management, investigating …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 2, 2025 · pp. 1–8 Read article
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The Clinical Landscape of Wogonin: Advancing Targeted Treatments for Chronic Diseases
Abstract: The traditional Chinese medicinal herb Scutellaria baicalensis Georgi, commonly known as Chinese skullcap or Huang-Qin, has long been used to treat a variety of conditions, including cancer, viral infections, and seizures. Its pharmacological effects are largely attributed to the high concentration of flavones, particularly wogonoside, and its aglycone derivative, wogonin. Among the bioactive compounds found in S. baicalensis, wogonin has garnered the most scientific attention due to its potent therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 46–52 Read article
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Problems and Difficulties in the Additive Manufacturing of Composites with Carbon Fiber Reinforcement for Medical Application
Abstract: Amputation is more prevalent than one may think due to an accident, war, or disease. Prosthetics and associated orthotics have a combined global market value of $2.8 billion. Carbon fibre has found a market due to increased demand for foot prostheses. Fused deposition modeling (FDM) is a rapidly advancing three-dimensional (3D) printing technique. PEEK (polyether-ether-ketone) is a biocompatible, high-performance polymer that could potentially be utilised as an orthopedic surgery implant …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 1, 2023 · pp. 8–12 Read article
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Examining the Effectiveness of Ventilator Bundles in Preventing Ventilator-Associated Pneumonia in Mechanical Ventilation Patients at Selected Hospitals in Nashik
Abstract: The objective of this study was to assess how the application of a ventilator bundle can effectively prevent cases of ventilator-associated pneumonia (VAP) in patients undergoing mechanical ventilation in designated hospitals in Nashik. The study adopted a quantitative evaluative approach, implementing a genuine experimental control group design. A total of 40 patients on mechanical ventilators were chosen, with 20 patients each assigned to the experimental and control groups through non-probability …
Published in Research and Reviews : Journal of Surgery · Vol. 12, Issue 2, 2023 Read article
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Understanding Leukemogenesis: Challenges and Advancements in Diagnostic Approaches
Abstract: Leukaemia development, or leukemogenesis, is a multifactorial process driven by a complex interplay of environmental, genetic, and epigenetic factors. Despite substantial advancements in technology and medicine, which have enhanced our understanding of the contributing factors, early and accurate diagnosis remains a major challenge due to the overlapping clinical features shared by the various leukaemia subtypes. This study explores the molecular and cellular mechanisms underlying leukemogenesis, while also addressing the difficulties …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 11–22 Read article
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Current Drugs Target the EGFR
Abstract: Cancer is a devastating disease, but there have recently been significant advancements in therapy that have identified EGFR and its related proteins as valuable indicators and targets for treatment. The ERBB receptor tyrosine kinase superfamily includes EGFR, which is a transmembrane glycoprotein. When the EGFR receptor interacts to its particular ligand, EGF, it causes tyrosine residues to be phosphorylated and forms receptor dimers with other members of the receptor family. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 1–8 Read article
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Neuropharmacological Mechanisms of Psychedelics: Advancing Treatment Strategies for Mental Health Disorder
Abstract: The resurgence of interest in the therapeutic potential of psychedelic drugs has caused a major upheaval in the field of psychiatry in recent years. This review's main goal is to thoroughly examine the possible benefits of psychedelic drugs in the field of psychiatry, with a focus on how they might be used as psychotherapy aids. Given their widespread use in therapeutic settings, clinical trials involving MDMA, psilocybin, ketamine, and LSD …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 67–79 Read article
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Repurposing Liv-52 For Primary Sclerosing Cholangitis: A Computational Docking And Pharmacokinetic Study To Evaluate Its Bile Flow-Regulating Potential
Abstract: Primary Sclerosing Cholangitis (PSC) is a long-term liver disease where the bile ducts become inflamed and scarred over time. This scarring can block the flow of bile, leading to liver damage and, eventually, liver failure. The etiology of PSC remains largely unknown, and current treatment options are limited, highlighting the need for novel therapeutic strategies. This study aims to repurpose Liv-52, a traditional herbal formulation known for its hepatoprotective properties, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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A Review: Homeopathic Remedies and Their Potential Neurological Implications in Depression and Asthma
Abstract: Homeopathy, based on the principle “like cures like”, has gained popularity as a complementary treatment for chronic diseases, including depression and asthma. Both health conditions have a profound impact on the quality of life of individuals and are often treated with pharmacological interventions such as antidepressants and bronchodilators. This review reviews homeopathic remedies used to treat depression and asthma, evaluating the available clinical evidence. Although some studies suggest that homeopathy …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 1, 2025 · pp. 15–20 Read article
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Ocular Films as a Drug Delivery System Against Fungal Infections: Current Insights and Future Directions
Abstract: Fungal infections of the eye, including keratitis, endophthalmitis, and blepharitis, represent a challenging class of ocular diseases due to their potential for vision loss and the limited efficacy of existing treatments. These infections are caused by a range of pathogenic fungi, such as Aspergillus, Candida, and Fusarium species, and often require long-term therapeutic intervention. Conventional topical antifungal therapies, such as eye drops and ointments, suffer from poor ocular bioavailability due …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 101–109 Read article
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Bedaquiline: An In-Depth Exploration into Its Antitubercular Significance
Abstract: Tuberculosis is still a leading infectious disease and a major threat to public health. Although there has been a slow decrease in the incidence over years, its “hard to kill nature” is responsible of about 2 million deaths in HIV infected individuals annually. Bedaquiline, a Diaryl-Quinoline drug was fast-track approved as an orphan drug to combat drug resistance. It shows potent activity against Mycobacterium tuberculosis by interfering with the production …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 06–14 Read article
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Causes and Measures to Control Root Rot Fungus in Mulberry Ecosystem
Abstract: Root rot is a severe plant disease caused by various soil-borne fungi, including Phytophthora sp., Pythium sp., Rhizoctonia sp., Fusarium sp., and Armillaria sp. These pathogens attack plant roots, leading to decay, stunted growth, wilting, yellowing leaves, and plant death. Root rot typically develops in waterlogged soils with poor drainage, as these conditions create an environment favorable for fungal growth. Factors such as warm temperatures, compacted soil, improper watering practices, …
Published in International Journal of Fungi · Vol. 1, Issue 2, 2024 · pp. 36–41 Read article
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Advancements in AI-Driven Sound Spectrogram Analysis: From Deep Learning to Quantum and Neuromorphic Processing
Abstract: The rapid advancement of artificial intelligence (AI) has significantly reshaped the field of audio signal processing, with sound spectrogram analysis emerging as a central research focus. Spectrograms provide a rich time–frequency representation of audio signals, making them particularly suitable for data-driven learning approaches. This paper presents an in-depth and original review of modern AI-based techniques applied to spectrogram analysis, highlighting their growing impact across critical application areas such as healthcare …
Published in Journal of Multimedia Technology & Recent Advancements · Vol. 13, Issue 1, 2026 · pp. 01–06 Read article
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Antimicrobial Resistance in Veterinary Medicine
Abstract: Antimicrobial resistance is a worldwide public health issue that impacts both human and animal populations. The use of antibiotics in veterinary medicine plays a significant role in the development and spread of antimicrobial resistance, contributing to resistant pathogens that impact both animals and humans. Antibiotics are widely utilized in animal husbandry, not only for treating diseases but also for preventing illness and enhancing growth in livestock. While this practice supports …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 3, 2024 · pp. 11–15 Read article
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Management of Varicose Veins: A Review of Literature
Abstract: Lower extremities venous insufficiency is a frequent disorder that can cause a variety of symptoms, such as ulceration, soreness, swelling, and bulging leg veins. Whereas there is many other treatment choices, the more recent endovascular treatments are simple, safe, rapid, and very effective at reducing symptoms. Foam sclerotherapy, thermal ablation, and mechanical chemical ablation are minimally invasive endovascular techniques commonly used in the treatment of varicose veins. This review article …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 1, 2025 · pp. 17–21 Read article
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Review on the Efficacy of Ayurvedic Formulations in Diabetes Management
Abstract: Diabetes mellitus is one of the most prevalent metabolic disorders globally, characterized by persistent hyperglycemia resulting from defects in insulin secretion, insulin action, or both. It leads to serious complications affecting the cardiovascular, renal, and nervous systems, imposing a significant health and economic burden. In Ayurveda, diabetes is described as Madhumeha, a subtype of Prameha, primarily caused by the vitiation of Kapha dosha, Meda dhatu (fat metabolism), and Agnimandya (impaired …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 1, 2026 · pp. 16–22 Read article
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Development of Biodegradable Stents from Polymeric Composites for Cardiovascular Applications
Abstract: Cardiovascular diseases are still one of the leading health complications in the world, and coronary artery disease remains one of the toughest ones to crack. The introduction of stent implantation in interventional cardiology is a breakthrough concept which helps to restore blood flow and maintain patency of the arteries. On the other hand, long-term results of bare-metal stents and drug-eluting stents indicate the presence of complications, such as in-stent restenosis, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 181–191 Read article
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Interrelationship Between Psychological Stress and Gastrointestinal Physiology: Role of the Gut–Brain Axis
Abstract: The relationship between stress and gut microbiome is a critical area of medical research underscoring the relativity and impact of psychological and emotional states on gastrointestinal (GI) health. This paper investigates the intricate relationship between stress and digestive health by analysing the influence of stress hormones, gut–brain interactions, and psychosocial determinants. Both acute and long-standing stress responses may disrupt normal gastrointestinal activity, affecting motility, secretion, intestinal microbiota, and overall digestive …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 2, 2026 Read article
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Interrelationship Between Psychological Stress and Gastrointestinal Physiology: Role of the Gut–Brain Axis
Abstract: The relationship between stress and gut microbiome is a critical area of medical research underscoring the relativity and impact of psychological and emotional states on gastrointestinal (GI) health. This paper investigates the intricate relationship between stress and digestive health by analysing the influence of stress hormones, gut–brain interactions, and psychosocial determinants. Both acute and long-standing stress responses may disrupt normal gastrointestinal activity, affecting motility, secretion, intestinal microbiota, and overall digestive …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 2, 2026 · pp. 30–35 Read article