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563 articles for “ADMET lab 2.0” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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How Microfluidics Are Used in Modern Science: Lab-on-A-Chip
Abstract: Microfluidics has changed modern research by making lab-on-a-chip (LOC) technologies that combine multiple lab functions into small, portable devices. These little platforms make it easier to correctly handle small amounts of fluid, which saves time, money, reagents, and automation. This article talks about microfluidics and how it helps LOC technology go forward in all areas of science. We look at important uses of biomedical diagnostics, drug development, environmental monitoring, and …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 2, 2025 · pp. 35–48 Read article
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Assessment of Finerenone Safety and Efficacy in Individuals with Type 2 Diabetes and Chronic Kidney Disease
Abstract: Background: In this work, we provide strong evidence for the safety and efficacy of finerenone in people with type 2 diabetes and chronic kidney disease. Our goal is to improve patients' quality of life and general well-being through our research. Aim: Finerenone exhibited a significant decrease in the likelihood of renal and cardiovascular (CV) events in individuals with both type 2 diabetes and chronic kidney disease. This exploratory subgroup analysis …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 06–09 Read article
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Effect of Reflex Zone Therapy on Labor Pain Among Antenatal Mothers: A Descriptive Study
Abstract: Background: Pregnancy and childbirth are considered the completion of a woman’s life. Pregnancy is a period of carrying a fetus in the womb of a mother. During the period of 9 months and 7 days, a pregnant woman may undergo several physiological and anatomical changes. Hence pregnancy is a special time of life in a woman’s life. Labor pain is an excruciating pain that lasts for several minutes to hours …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 1–6 Read article
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Experiences of Women with the Labour and Delivery Care Received at Mzimba District Hospital, Malawi
Abstract: Aim: The aim of the study was to explore the perceptions of women on the care that they received during normal labour and delivery at Mzimba District Hospital, Malawi. Specific Objectives: To evaluate the aspects of physical care that was rendered to women during labour and delivery, evaluate the psychological care that was rendered to women throughout labour and delivery, assess the perception of women on the attitudes of midwives …
Published in International Journal of Women's Health Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 37–46 Read article
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Effectiveness of Video-assisted Teaching on Anxiety Related to Labor Process and Preparation for Labor Among the Primigravida Mothers Attending Antenatal OPD at GMCH-32 Chandigarh
Abstract: Aims and background: A randomized control trial to assess the effectiveness of video-assisted teaching on anxiety related to labor process and preparation for labor among primigravida mothers attending antenatal OPD of GMCH-32, Chandigarh, was carried out in full compliance with ethical standards laid down by the Research and Ethical Committee of GMCH-32, Chandigarh. Method: A systematic random sampling technique was used to select 80 subjects, 40 each in control and …
Published in International Journal of Midwifery Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 9–13 Read article
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COVID-19 Resurgence in 2025: India’s Continuing Public Health Challenge
Abstract: The year 2025 has witnessed the resurgence of COVID-19, reigniting concerns at both global and national levels regarding the persistent threat posed by SARS-CoV-2. In early 2025, India witnessed a moderate resurgence of COVID‑19, characterized by the emergence of Omicron sub-variants and a rise in mild-to-moderate infections. As of mid-June, active COVID‑19 cases in India totaled approximately 6,000–7,400, with hotspots in Kerala (~2,100 cases), Delhi (~600), Maharashtra (~500), and several …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 16–23 Read article
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Deciphering the Roles of Estrogen Receptors and 27-Hydroxycholesterol in BC Progression
Abstract: Breast cancer (BC) ranks among the top causes of cancer-related deaths in women worldwide. Many risk factors of BC are linked to estrogen. Experiments of Beatson in 1896 show the role of steroid hormones as major determinant in BC. Action of steroid hormones is mediated by their receptors including Estrogen receptors (ERs). ERs are part of a subfamily of ligand-regulated transcription factors. Their primary role is to translate hormone signals …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 18–26 Read article
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The Role of Indigenous Knowledge Systems in Cultural Heritage Preservation under NEP 2020
Abstract: In Introduction, This study explores the roles of India’s National Education Policy (NEP) 2020 in cultural heritage preservation through indigenous knowledge systems. These include traditional arts, crafts, ecological practices, and languages. It also includes perspectives through gender and regional lenses on this integration. In Methodology, Confirming the study, a survey was held with 2,300 participants, with an equal split of male, female and non-binary, from rural and urban settings. The …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 2, 2025 · pp. 22–30 Read article
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Studies On The Length-Weight Relationship And Morphometric Characteristics of Rohu, Labeo Rohita (Hamilton) From Pond In Radhamohanpur, Jirania, Tripura, India
Abstract: The present study describes the length–weight (LWR) relationship and morphometric characters of 30 specimens of the rohu, Labeo rohita (Hamilton) collected from the pond situated in Radhamohanpur, Jirania, Tripura, India over a period of six months extending from (January 2020-June 2020). The fish were caught by traditional fishing gear. Total length (TL) reading has been taken from Vernier Calliper and Body weight (BW) measured with digital balance. The readings of …
Published in International Journal of Marine Life · Vol. 1, Issue 2, 2024 · pp. 27–34 Read article
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Investigation of Pollution Status in River No. 2, Freetown, Sierra Leone, Using Physicochemical and Bacterial Indicators
Abstract: This study assessed the physicochemical and bacteriological quality of surface water in the River No. 2 watershed, Sierra Leone, through monthly sampling from March–August 2024 at upstream, midstream, and downstream sites. Analyses included temperature, turbidity, pH, electrical conductivity, total dissolved solids, ammonia, fluoride, sulfite, nitrate, lead, arsenic, chromium, and microbial indicators (Escherichia coli, fecal and non-fecal coliforms). Most physicochemical parameters met WHO drinking-water guidelines. pH (7.0–7.3), TDS (7–17 mg/L), turbidity …
Published in International Journal of Pollution: Prevention & Control · Vol. 4, Issue 1, 2026 · pp. 11–27 Read article
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The Evolution of Asthma Management: A Comprehensive Analysis of GINA 2024 Guidelines, Endotype-Driven Diagnosis, and Targeted Biologic Intervention
Abstract: Asthma remains a substantial global public health challenge, characterized by heterogeneous airway inflammation leading to variable airflow obstruction. Recent advances in personalized medicine and guideline revisions, notably the Global Initiative for Asthma (GINA) 2024 update, mandate a profound paradigm shift from reliance on short-acting beta2-agonists (SABA) to antiinflammatory reliever (AIR) strategies utilizing inhaled corticosteroid (ICS)-formoterol. This report provides an exhaustive analysis of current asthma epidemiology, molecular pathogenesis distinguishing between Type …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 2, 2026 Read article
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Role of Inflammatory Markers and Lipid Abnormalities in Glycemic Dysregulation Among Type 2 Diabetics
Abstract: Background: Diabetes mellitus (DM) is a chronic metabolic disorder characterized by systemic inflammation and associated with various complications in multiple organs. Type 2 diabetes mellitus (T2DM) specifically involves insulin resistance, hyperglycemia, and inflammatory responses. This study investigates the levels of various inflammatory markers and their correlation with glycaemic control in T2DM patients. Objective: To evaluate the levels of inflammatory markers (including NLR, PLR, SII, SIRI, CRP, IL-6, TNF-α, TGF-β, MCP-1, …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article
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Grid based docking study of some 2-(4-methylsulfonyl phenyl) pyrimidine derivatives (designed after QSAR studies) with Cyclooxygenase
Abstract: Molecular docking helps in studying drug/ligand or receptor/ protein interactions by identifying the suitable active sites in protein, obtaining the best geometry of ligand-receptor complex and calculating the energy of interaction for different ligands to design more effective ligands. In Grid based docking, after unique conformers of the ligand are generated, the receptor cavity of interest is chosen and a grid is generated around the cavity. Cavity points are found …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 23–41 Read article
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Reimagining Teacher Education in India: Evaluating NEP 2020’s Impact and Implementation Challenges
Abstract: India's educational system has undergone a substantial change with the implementation of the National Education Policy (NEP) 2020, which places a special focus on enhancing teacher preparation. The policy, which was endorsed by the Union Cabinet on July 29, 2020, was crafted by a commission led by former ISRO Chairman Dr. K. Kasturirangan, who defined the vision for the country’s updated education system. The NEP addresses various challenges within the …
Published in International Journal of Education Sciences · Vol. 2, Issue 1, 2025 · pp. 9–13 Read article
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An Efficient Synthesis of Some Novel Benzo Coumarin Derivatives Under Solvent Conditions from 2-acetyl-benzo[f]chromen-3-one
Abstract: The synthesis of the target compounds began with the preparation of 2-[3-dimethylamino[acryloyl-3H-benzo[f]chromen-3-one. This intermediate was obtained through the reaction of 2-acetylbenzo[f]coumarin-3-one with N,N-dimethylformamide dimethyl acetal [DMFDMA[ under reflux conditions in xylene. The enaminone thus formed was subsequently reacted with 6-aminothiouracil in acetic acid, leading to the formation of 2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one. This compound served as a pivotal intermediate for the synthesis of a series of pyridotriazolopyrimidinones. These derivatives were synthesized by reacting …
Published in International Journal of Cheminformatics · Vol. 2, Issue 2, 2024 · pp. 33–46 Read article
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In Silico Molecular Docking of Indigofera tinctoria Phytocompounds to Target EGFR/ERK and FGFR/FGF Pathway Proteins Involved in Prostate Cancer
Abstract: Objective: Prostate cancer being the second major cause of cancer-related deaths in males, affects the small walnut-shaped gland below the bladder called the prostate gland. The epidermal growth factor protein (EGFR), cascade protein (ERK), and fibroblast growth factor proteins (FGFR and FGF) are involved in the different signaling pathways that lead to the formation of different products, that are responsible for the progression of cancer and thus can be considered …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 34–56 Read article
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Molecular Docking and Pharmacokinetic Profiling of the Phytocompounds of Jatropha curcas as Antagonist for Salmonella typhi
Abstract: Background: Typhoid is an infection caused by the Gram-negative bacterium, Salmonella enterica serovar typhi. The study assessed the potential use of Jatropha curcas as a typhoid fever therapy alternative to traditional medications. The ability to uncover novel drug indications for currently available medications using in silico methods has increased thanks to the wealth of pharmacological and biological knowledge that is available. Objective: In this study, we assessed the potential inhibitory …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 67–81 Read article
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Effectiveness of a Planned Teaching Programme on Primigravid Mothers' Awareness of Specific Natural Pain Relief Techniques Used During Labor in Particular Bangalore Hospital
Abstract: Background: Pain is an exciting sensation and is caused by the stimulus during labor. Always Pain plays a major role in labor in empowering the women, whereby they triumph by giving delivery to the newborn. Objectives: Assess the knowledge level about selected natural pain relief methods. Methodology: A quantitative research approach and the design used in this study was a pre-experimental research design. Sixty primigravid mothers were selected for the …
Published in International Journal of Midwifery Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 9–16 Read article
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Addressing Accountability and Fair Practices in Labor Contracting for Sustainable Harvesting in the Sugar Industry
Abstract: This study promotes the use of blockchain technology to solve issues with labor data management in the sugar business. Through decentralized blockchain storage, the proposed solution protects the security and openness of labor data, with an emphasis on preventing unethical activity by contractors holding numerous simultaneous contracts. Smart contracts make it easier for contractors to register and keep track of engagements, which helps the sugar industry enforce contractual compliance and …
Published in International Journal of Solid State Innovations & Research · Vol. 2, Issue 1, 2024 · pp. 1–7 Read article