All articles

Published Subscription Review Article 7 Feb 2025

Utilize Nature’s Power: Nutraceuticals in the Fight Against Dengue

By Mohd. Wasiullah, Piyush Yadav, Azhan Ahmad

Abstract: As dengue fever continues to surge across tropical and subtropical regions, the exploration of novel therapeutic approaches is crucial. Nutraceuticals, natural bioactive compounds derived from food sources, are emerging as promising adjuncts in the fight against this viral disease. Unlike conventional treatments that primarily target symptoms, nutraceuticals offer a complementary strategy by enhancing the body’s immune defense and addressing key complications. This review highlights the diverse potential of nature’s remedies, …

Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 1, 2025 · pp. 19–27 Read article

Published Subscription Original Research 7 Feb 2025

Climate Change and Respiratory Allergy

By P.C Kathuria, Manisha Rai

Abstract: Climate change, a global issue, directly and indirectly impacts human health while posing a significant threat to animals and ecosystems. As part of the exposome, it influences various factors like seasonality, production, and the distribution of airborne allergens due to rising carbon dioxide levels and temperatures. These environmental changes also contribute to increased epithelial permeability, microbial imbalances, and heightened allergic reactions to pollen and fungal spores. Earth’s average surface temperature, …

Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 1, 2025 · pp. 28–41 Read article

Published Subscription Review Article 21 Jan 2025

Alternative Medicine: A Review Article the Lupus Journey from the Diagnosis to Recovery and Beyond

By Mohd. Wasiullah, Piyush Yadav, Vishal Prajapati, Pragati Yadav

Abstract: Lupus, a chronic autoimmune disease, presents a complex and often volatile journey for patients, from diagnosis to recovery and beyond. The course is usually characterized by periods of acute flare-ups, followed by remissions, with different symptoms affecting different organ systems. This review delves into managing lupus with alternative medicine, highlighting how it can work alongside conventional treatments. It covers topics like diet, herbal remedies, acupuncture, and mind-body practices, all aimed …

Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 1, 2025 · pp. 9–18 Read article

Published Subscription Original Research 15 Jan 2025

The Prognostic Efficacy of Inflammatory Indicators in Determining the Cause of Multiple Sclerosis Exacerbation

By Rajiv Shrestha

Abstract: Multiple sclerosis (MS) is the most prevalent immune-mediated inflammatory disease affecting the central nervous system, presenting with diverse clinical symptoms and manifestations. This study investigates the diagnostic potential of the monocyte-to-lymphocyte ratio (MLR), red cell distribution width-to-lymphocyte ratio (RLR), and systemic immune-inflammation index (SII) in detecting MS attacks among relapsing-remitting MS (RRMS) patients seeking care in the emergency department (ED). The research focused on RRMS patients who presented to the …

Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 1, 2025 · pp. 1–8 Read article

Published Subscription Original Research 4 Jan 2025

Exploring Challenges in Clinical Learning and the Impact of Structured Teaching on Infection Control Knowledge and Attitudes Among Nursing Students

By Bhawana Bisen

Abstract: Living a healthy lifestyle is essential for preventing chronic diseases and maintaining physical, psychological, and social well-being. The present study, titled “Exploring Challenges in Clinical Learning and the Impact of Structured Teaching on Infection Control Knowledge and Attitudes among Nursing Students” aimed to address key challenges faced by nursing students and evaluate the impact of a structured teaching program. The study employed a quantitative research approach using a pre-experimental design …

Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 1, 2025 · pp. 42–47 Read article

Published Subscription Review Article 15 Nov 2024

Targeting TNFSF4 in the Management of Systemic Lupus Erythematosus

By Preeti Shanbhag, Ramdas Bhat

Abstract: Systemic lupus erythematosus (SLE) is a multifaceted autoimmune disorder that remains a significant challenge for both healthcare providers and researchers. Despite advances in understanding its mechanisms, finding effective therapies is still difficult. This review highlights a potential therapeutic target in SLE research: tumor necrosis factor superfamily member 4 (TNFSF4), also referred to as OX40L. We explore how TNFSF4 contributes to SLE development, looking at its role in immune system regulation …

Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 6–14 Read article

Published Subscription Review Article 15 Nov 2024

Gut Feelings: Unravelling the Secrets of the Microbial Universe Within

By Yashashwi Shrivastav, Sanika Balekar, Neelam Balekar

Abstract: The human digestive system hosts a varied and dynamic community of microorganisms, commonly known as the gut microbiota. This complex community, which includes various organisms such as bacteria, archaea, viruses, and fungi, is essential and important for numerous bodily functions such as metabolism, immune response, and cognitive development. The composition and vast diversity of the gut microbiome are shaped by diet, lifestyle, and genetic factors. Disruptions in this balance, known …

Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 21–33 Read article

Published Open access Review Article 14 Nov 2024

A Review Article on the Human Blood Groups in Relation to Healthy Longevity

By Ashutosh Mishra, Pankaj Kumar Mishra, Dev Brat Mishra

Abstract: After significant discovery of the ABO blood groups of human beings by Karl Landsteiner, a number of works have been carried out on different types of blood groups like MN type, Q types, etc. and in the same time, number of researches were also carried regarding different aspects of blood groups like its genetic analysis, its inheritance, its role in paternity test, its role in blood transfusion and general physiology …

Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 1–5 Read article

Published Subscription Review Article 14 Nov 2024

Disease X: Unveiling the Unknown Pathogen and Enhancing Global Preparedness

By Archana Reddy

Abstract: “The concept of “Disease X” was introduced to drive the creation and refinement of versatile technologies such as vaccines, therapeutic drugs, and diagnostic tests, which could be swiftly adapted and utilized in response to future infectious disease outbreaks with epidemic or pandemic potential. The aim was to establish a proactive approach to emerging health threats by developing platform technologies capable of addressing a broad spectrum of potential pathogens. The COVID-19 …

Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 15–20 Read article

Published Subscription Review Article 14 Nov 2024

Multiple Disease Prediction Using Machine Learning Algorithms

By Ankit Sharma, A. N. Kshirsagar, Anish Kannawar, Abhishek Mishra

Abstract: The incorporation of machine learning algorithms into healthcare has transformed disease prediction and diagnosis. This research introduces a method for predicting various diseases using machine learning techniques. A comprehensive dataset, consisting of patient records, medical histories, and key disease-related features, was utilized to build predictive models. Data preprocessing methods, including feature selection and normalization, were implemented to clean and prepare the dataset. Several machine learning algorithms, such as Decision Trees, …

Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 34–38 Read article

Published Subscription Review Article 16 Aug 2024

Computer-Aided Drug Design on Tuberculosis

By Mohd Wasiullah, Piyush Yadav, Harsh Sahu, Satish Kumar Yadav, Vinay Kumar Deepak

Abstract: Currently, India's Directly Observed Treatment Short Course (DOTS) program is the world's largest and fastest-growing initiative for treating medical patients, second only in terms of population coverage. The main obstacles to TB control in India are inadequate primary healthcare in rural regions of many states, unregulated private treatments resulting in extensive misuse of first- and second-line TB medications, the spread of HIV, a lack of political commitment, and, most importantly, …

Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 22–31 Read article

Published Subscription Review Article 16 Aug 2024

Wiskott-Aldrich Syndrome: A Comprehensive Guide

By Kamini P. Sao

Abstract: Wiskott-Aldrich Syndrome (WAS) is an uncommon genetic disorder inherited through the X chromosome, marked by a combination of immune system deficiencies, eczema, and low platelet counts. This syndrome primarily affects males, leading to significant morbidity and mortality due to recurrent infections, bleeding complications, and autoimmune diseases. Mutations in the WAS gene disrupt the production of the Wiskott-Aldrich Syndrome protein (WASp), crucial for the functioning of immune cells and platelet formation. …

Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 39–46 Read article

Published Subscription Review Article 16 Aug 2024

Angioedema-Diagnosis & Management

By P.C Kathuria, Manisha Rai

Abstract: Angioedema (AE) encompasses a diverse range of conditions categorized into three main groups: (1) angioedema mediated by histamine (AE-H); (2) angioedema mediated by bradykinin (AE-BK); and (3) angioedema with an unknown mechanism (AE-UNK). It can manifest on any part of the body, though commonly affected areas include the face, lips, mouth, throat, larynx, extremities, genital regions, and gastrointestinal tract. AE-H can occur by itself or in conjunction with chronic urticaria, …

Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 9–21 Read article

Published Subscription Original Research 2 Aug 2024

Evaluation Tumor Necrosis Factor-α (TNF- α) Levels in Patients with Rheumatoid Arthritis

By Ali S. Shakir

Abstract: Background: RA is an inflammatory, long-term autoimmune illness, that is impacted by external variables, according to a report from the World Health Organization. Women are 2-3 times more likely than men to develop RA, though this difference diminishes with older age at onset. Aim: The purpose of this study is to assess the significance of TNF-α concentrations in the predisposition to rheumatoid arthritis. Methods: The research project enrolled 100 patients …

Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 32–38 Read article

Published Subscription Review Article 9 Jul 2024

Computer-aided Drug Design Method for Anti-hepatitis C Drug Design

By Mohd Wasiullah, Piyush Yadav, Tabish Ansari, Satish Kumar Yadav, GrijeshYadav

Abstract: Hepatitis C is a disease caused by the hepatitis C virus and can cause serious liver damage. There is currently no vaccine for this disease and the number of infections continues to increase worldwide. Currently used antiviral drugs are interferon alfa-2a and ribavirin, but about half of patients do not respond to therapy. Therefore, new drugs that protect against hepatitis C need to be investigated. Computational drug methods have been …

Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 1–8 Read article