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834 articles
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Evaluating the Benefits of Lift Procedure for Fistula in Ano: A Peripheral Centre Experience
Abstract: Introduction: Surgery is considered the only definitive treatment for anal fistula. Many surgical techniques have been described. The aim of this study was to communicate the authors’ preliminary experience in the use of a very recent, simplified technique, at a peripheral surgical centre. Patients And Methods: This was a retrospective study of 10 patients of Fistula-in-ano admitted from October 2021 through September 2023. Patients were managed with the ligation of …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 17–20 Read article
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Correlation of Outcome of Scars with Comorbidities Following Er YAG Laser
Abstract: The scar is a sequela of any form of trauma. The abnormal scar can influence an individual’s well beingness. The prevention, as well as treatment of scars, is important. The scar makes a good percentage of consultations in any Plastic Surgery department or dermatology department. There are many methods to manage a scar, Laser Therapy using Er YAG laser is one method of management of scars that are widely used. …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 12–16 Read article
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Effect of Valsalva Maneuver Prior to Cannulation on Pain Among Patients Undergoing Peripheral Venous Cannulation
Abstract: Peripheral venous canulation is the common nursing procedure carried out which cause soreness to the recipient. Previous experience of peripheral venous cannulation may result in negligence or delay in need of medical care. Valsalva Maneuver is a non-pharmacological and cost- effective method to decrease intensity of pain during peripheral venous cannulation. Aim: To assess the effect of Valsalva Maneuver prior to cannulation on pain among patients undergoing peripheral venous cannulation. …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 1–6 Read article
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Exploring Biomedical Innovations in the Formulation and Assessment of Medicated Hard Candy Lozenges Containing Metoclopramide Hydrochloride
Abstract: The objective of this study was to formulate and evaluate metoclopramide hydrochloride medicated lozenges for antiemetic action through buccal absorption by incorporating a polymer. All formulations were developed and assessed for in-vitro drug release, physical appearance, weight variation, thickness, hardness, moisture content, mouth-dissolving time, and drug content. The prepared lozenges exhibited uniformity in weight and thickness. The hardness of all formulations ranged between 7.3–15.50 kg/cm², falling within standard limits. The …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 50–62 Read article
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Development of Formulation for Dry Powder Inhalation of Amino Acids Aimed at Smoking Cessation: A Biomedical Perspective
Abstract: This study aims to develop an effective and compliant therapy targeting the lungs through the strategic utilization of amino acids, which play a crucial role in modulating mood and behavior during activities like smoking. L-Tryptophan and L-Tyrosine were finely micronized within the 2–4 µm range, with lactose serving as a carrier, to create a dry powder inhalation formulation. The combination of these amino acids is anticipated to elicit a synergistic …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 18–36 Read article
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Role of Gastric Receptors in Gastrointestinal Disorder
Abstract: The established and potential roles of cholecystokinin1 and cholecystokinin2 receptors in gastrointestinal and metabolic diseases are analyzed, along with findings from human studies involving agonists and antagonists. While there is considerable evidence implicating cholecystokinin1R in various diseases such as pancreatic disorders, motility disorders, tumor growth, satiety regulation, and cholecystokinin-deficient states, its specific role in these conditions remains ambiguous. Conversely, the role of cholecystokinin2R in physiological (e.g., atrophic gastritis) and pathological …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 37–49 Read article
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Oligomenorrhea: An Overview in Toxicology
Abstract: In the contemporary era characterized by a swift and cutthroat environment, numerous gynecological issues are on the rise owing to sedentary lifestyles, improper dietary patterns, and other factors. The interaction between physical and mental health significantly affects the menstrual cycle. According to data, a staggering 80% of women grappling with irregular menstrual cycles find themselves in the grips of Oligomenorrhea, constituting 19.3% of this demographic. In today’s fast-paced and competitive …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 2, 2024 · pp. 45–51 Read article
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Role of Application of SWCR Guidelines in Management of Right Trochanter Pressure Injury (PI)
Abstract: A pressure injury refers to the localized death of tissue resulting from sustained pressure on the skin and underlying tissues. This damage is often compounded by shear forces or direct trauma to the skin. While terms like “decubitus ulcer,” “bedsore,” and “pressure sore” are commonly used interchangeably, they fail to capture the complexity of the condition as accurately as the term “pressure injury” does. The term “decubitus” originates from Latin, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 2, 2024 · pp. 30–40 Read article
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Toxicology-Focused Development and Validation of an RP-HPLC Technique for Quantifying Bempefoic Acid and Rosuvastatin in a Fixed-Dose Combination
Abstract: A straightforward, precise method was developed to simultaneously assess Bempedoic acid and Rosuvastatin in both bulk and tablet forms. Utilizing a DIKMA Spursil C18 column (4.6 mm x 250 mm, 3.0 μm), chromatography was conducted with a mobile phase comprising 30% phosphate buffer and 70% acetonitrile, flowing at 1 ml/min. Operating at ambient temperature, the optimized wavelength for detection was set at 240 nm, revealing retention times of 4.418 min …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 2, 2024 · pp. 1–9 Read article
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Role of Low Level Laser Therapy (LLLT) in Healing of Electric Burns
Abstract: The objective of this case study is to evaluate the effectiveness of low-level laser therapy (LLLT) in treating scalp wounds caused by electric burns. A thorough examination of the scalp wound was conducted both before and after administering LLLT. The findings suggest that LLLT plays a beneficial role in the healing process of superficial ulcers. Specifically, the application of LLLT (as depicted in Figure 1) demonstrated promising results in facilitating …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 2, 2024 · pp. 39–44 Read article
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Bioinformatics-based Preparation and Characterization of Silver Nanoparticles Synthesized from Pterocarpus marsupium
Abstract: Silver nanoparticles were synthesized using Pterocarpus marsupium bark extract in combination with silver nitrate solution through a green synthesis method. Silver nanoparticles formation was confirmed by the formation of dark brown from solution of silver nitrate, where the reduction of silver ion occurs which leads to the formation of silver nanoparticles. The UV–visible spectra showed a peak at 429 nm, confirming the reduction of silver ions and the subsequent synthesis …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 2, 2024 · pp. 21–34 Read article
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Exploring Diabetic Retinopathy from an Ayurvedic Lens: Insights Leveraging Bioinformatics
Abstract: Diabetic retinopathy is one among the target diseases for VISION 2025. The huge cost required for treatment, economic loss due to absenteeism from work etc... has made it as a great public challenge. Therefore it is in need of the hour to address the issues of diabetes mellitus with its complication Diabetic Retinopathy with all seriousness and it is quite essential to search for a affordable medical care for the …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 2, 2024 · pp. 45–51 Read article
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Panfacial Trauma- A Case Report
Abstract: The majority of panfacial fractures are accompanied by concurrent organ damage. Panfacial fracture management is difficult and necessitates careful planning, sequencing, and sufficient understanding of the anatomy and management of the condition. In any trauma situation, the ABCDEs (airway, breathing, circulation, disability, and exposure) always remain the primary care priorities. Maxillofacial surgeons are essential in the early stabilization of fractures, the management of localized bleeding into the face, and the …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 2, 2024 · pp. 21–25 Read article
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Socket Preservation: Review
Abstract: The removal of a tooth results in remodeling and absorption not only within the socket but also in the surrounding alveolar bone. Alterations in the bone ridge following extraction are unavoidable, influenced by the initial size of the socket, with wider sockets requiring more time to heal completely. Both the height and width of the bone undergo dimensional changes subsequent to tooth extraction.The volumetric bone reduction changes occur after tooth …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 2, 2024 · pp. 8–13 Read article
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Modern Computer-aided Drug Design Methods: A Review
Abstract: Computer-aided drug design (CADD) has emerged as a crucial tool in the drug discovery process, offering a time-efficient and cost-effective approach to identifying potential drug candidates. This review aims to provide an overview of modern CADD methods, including high-throughput screening (HTS), structure-based drug design (SBDD), ligand-based drug design (LBDD), structure-based virtual screening (SBVS), and ligand-based virtual screening (LBVS). We discuss the basic principles, applicability, and limitations of each method, highlighting …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 2, 2024 · pp. 14–20 Read article
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Comparison of Knowledge Perceived by Final Year Dental Students for a Lesson on the Apical Barrier in the Premature Root by Clinical Case Demonstration as Compared to the Didactic Teaching Method
Abstract: The present dental education is using didactic teaching method, which is teacher-centered with minimal or no active participation from the students. Case-based learning (CBL) is defined as learning that is based upon description of a patient’s problems, analysis and interpretation of all the relevant data obtained from history, examination and investigations and planning for further management of patient. The goal of CBL is to prepare students for clinical practice, by …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 2, 2024 · pp. 1–7 Read article
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Enhancing Human Welfare In The Gig Economy: A Comprehensive Exploration Of Health And Safety Challenges
Abstract: This abstract provides a comprehensive overview of the health and safety challenges facing gig workers in the expanding gig economy. It highlights the diverse range of risks gig workers encounter, from physical hazards to psychological stressors, exacerbated by the absence of traditional employer-employee relationships. Despite these challenges, the abstract underscores the potential for innovative solutions, such as technological advancements and collaborative efforts among stakeholders, to improve worker well-being. By emphasizing …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 70–77 Read article
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Development of Spanish Version of Home-Based Video Module of Balance Exercises for Peripheral Vestibular Disordered Patients
Abstract: Any disturbances affecting one or more of the balance organs lead to imbalance difficulties and as a consequence, the quality of life of the affected individuals can be seriously affected, especially if the episodes end with injuries or even fatal accidents. Bal Ex is the first home-based video guided workout that was created by Zainun and her colleagues in 2009. Ten languages are currently supported by Bal Ex, including Cantonese, …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 33–41 Read article
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Editorial: Advancements in Movement Analysis for Understanding Neurological Disorders
Abstract: Neurological disorders pose a significant challenge, demanding innovative approaches for accurate diagnosis, effective treatment, and deeper understanding. Movement analysis emerges as a powerful tool, offering a quantitative window into the complexities of motor function. This editorial delves into the transformative impact of movement analysis on neurological research and clinical practice. Traditional diagnostic methods, reliant on subjective observations, often miss subtle motor impairments, particularly in early disease stages. Movement analysis tackles …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 28–32 Read article
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Nutraceuticals: Bridging Nutrition and Medicine for Future Wellness
Abstract: Nutraceuticals are items that can be classified as food or a component of food and provide medical or health benefits. This paper discusses the concept of nutraceuticals, their classification, and their role in promoting health and wellness. As of 2023, the worldwide nutraceuticals market is expected to be valued at approximately USD 317.22 billion, indicating a high rate of increase. Growth is projected to reach USD 626.02 billion by 2029 …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 26–36 Read article