All articles
834 articles
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Disease X: Unveiling the Unknown Pathogen and Enhancing Global Preparedness
Abstract: “The concept of “Disease X” was introduced to drive the creation and refinement of versatile technologies such as vaccines, therapeutic drugs, and diagnostic tests, which could be swiftly adapted and utilized in response to future infectious disease outbreaks with epidemic or pandemic potential. The aim was to establish a proactive approach to emerging health threats by developing platform technologies capable of addressing a broad spectrum of potential pathogens. The COVID-19 …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 15–20 Read article
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Multiple Disease Prediction Using Machine Learning Algorithms
Abstract: The incorporation of machine learning algorithms into healthcare has transformed disease prediction and diagnosis. This research introduces a method for predicting various diseases using machine learning techniques. A comprehensive dataset, consisting of patient records, medical histories, and key disease-related features, was utilized to build predictive models. Data preprocessing methods, including feature selection and normalization, were implemented to clean and prepare the dataset. Several machine learning algorithms, such as Decision Trees, …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 34–38 Read article
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To study aims to compare the pain relief effects of a single intravenous dose of paracetamol and fentanyl in patients undergoing elective surgery
Abstract: Objective: Effective pain management during and after surgery is vital for ensuring patient comfort and promoting recovery. While intravenous (IV) paracetamol and fentanyl are commonly administered for pain relief, their effectiveness in elective surgeries continues to be a subject of debate. Methods: In this future-oriented randomized controlled experiment the goal was to investigate the effectiveness of administering IV paracetamol and IV fentanyl for managing pain during and after scheduled elective …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 1–14 Read article
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Deep Learning-Based Pneumonia Diagnosis: A Comparative Review of Models and Metrics
Abstract: Pneumonia is a common viral infection that affects a large percentage of people worldwide. It is more common in developing and impoverished areas because of factors like poor sanitation, crowded living quarters, pollution in the environment, and restricted access to medical facilities. In order to improve survival chances and gain access to therapeutic therapies, pneumonia must be diagnosed as soon as possible. A type of artificial intelligence called deep learning …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 Read article
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Weight Loss Surgery Induced Telogen Effluvium (We Loss SITE) Management – Our Experiences
Abstract: Telogen effluvium, a condition of non-inflammatory, no-scarring, diffuse hair loss after weight loss surgery. A through history taking and videodermatoscopy is an effective tool for evaluation of a patient with weight loss surgery-induced teleogen effluvium (We Loss SITE). Cyclical nutritional therapy, low level laser therapy, autologous platelet rich plasma are effective treatments for telogen effluvium. This case report shares our experience in the management of a patient with weight loss …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 Read article
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The Analysis of Deep Learning-Based Methods for Identifying Diabetic Retinopathy
Abstract: Diabetic retinopathy (DR) is a degenerative eye condition resulting from diabetes mellitus, where high blood glucose levels lead to lesions on the retina. This condition is considered the leading cause of blindness among working-age diabetic patients, particularly in developing countries. As the disease is irreversible, the treatment aims to preserve the patient’s current vision. Early detection is crucial for effective management of DR to maintain vision. One of the main …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 15–31 Read article
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Evaluating the Impact of the Valsalva Maneuver on Pain Relief During Intravenous Cannulation in Patients at Selected Hospitals in Tirupati, Andhra Pradesh
Abstract: Pain can be defined as an unpleasant tactile sensation, arousing sensory experience, and an emotional response that is linked to any type of tissue, cell, or skin damage. Pain is a very common and a primary reason for which people seek health care. Among all the non-pharmacological methods for pain relieving, the Valsalva maneuver is one of the methods which is found effective in reducing the level of pain a …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 Read article
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Role of Nail Pilar Assisted Dermabrasion in Scald Burns
Abstract: Second-degree deep dermal and full-thickness burn injuries tend to heal slowly and often result in scarring. Deep dermal burns, which extend beyond the superficial layers of the skin, require prompt and specialized medical intervention to promote effective healing. While superficial burns, which involve only the epidermis and superficial dermal layers, can often be managed through wound irrigation, debridement, and standard local wound care, deeper burns present more complex challenges. In …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 Read article
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A Comprehensive Review of Digital Transformation in Healthcare: Addressing Privacy, Security, and Usability Challenges in Electronic Health Records
Abstract: The healthcare industry’s shift toward digitalization through electronic health records (EHRs) and advanced health information technology (HIT) promises improved patient care but brings forth challenges in safeguarding patient data privacy, confidentiality, and security (PCS). Researchers are exploring innovative solutions like block chain and cryptography to address these concerns while ensuring usability for healthcare professionals. Additionally, the impact of regulatory frameworks on data sharing and security is being studied, emphasizing the …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 9–14 Read article
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Investigating the Impact of Viral Infections on Pharmacokinetics and Pharmacodynamics of Antiviral Drugs
Abstract: The emergence and re-emergence of viral infections pose significant challenges to public health, necessitating a comprehensive understanding of how these infections impact the pharmacokinetics and pharmacodynamics of antiviral drugs. This review explores the intricate interactions between viral pathophysiology and the pharmacological effects of antiviral agents. Factors such as viral replication dynamics, host immune responses, and the genetic variability of both viruses and hosts significantly influence drug absorption, distribution, metabolism, and …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 23–30 Read article
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The Role of Natural Products in Antiviral Drug Discovery: Insights into Mechanisms and Therapeutic Potential
Abstract: Drug discovery has always relied heavily on natural sources, especially when it comes to creating antiviral medications. This review explores the therapeutic potential of various natural products, including plant extracts, marine compounds, and microbial metabolites, in the fight against viral infections. We examine the mechanisms of action by which these natural compounds exert their antiviral effects, including direct inhibition of viral replication, modulation of host immune responses, and interference with …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 36–47 Read article
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Review of Current Trends in Vaccine Development against Zoonotic Viruses: Challenges and Innovations
Abstract: The emergence of zoonotic viruses poses a significant threat to global public health, necessitating rapid advancements in vaccine development. This review highlights the current trends and innovative strategies employed in the creation of vaccines against zoonotic pathogens, including but not limited to viruses responsible for diseases such as Ebola, Zika, Nipah, and more recently, SARS-CoV-2. We discuss various vaccine platforms, including inactivated, live attenuated, mRNA, and viral vector vaccines, focusing …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 1–11 Read article
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Development of a Novel Therapeutic Approach Using RNA Interference for Targeting Viral Genes
Abstract: RNA interference (RNAi) is a ground breaking therapeutic strategy that holds immense promise for targeting viral genes in the treatment of viral infections. This approach leverages the natural gene-silencing mechanisms of RNAi to inhibit viral replication and expression at the molecular level, providing a precise and adaptable method to counteract viral pathogens, including influenza, HIV, and hepatitis viruses. Recent advancements in RNAi technology have enabled the development of highly specific …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 12–22 Read article
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Bacteriophages- A New Frontier in Medicine
Abstract: Bacteriophages, or phages, are viruses that specifically target and infect bacteria, offering an innovative alternative to traditional antibiotic treatments, especially in the face of rising antibiotic resistance. The resurgence of phage therapy has been driven by the increasing prevalence of multidrug-resistant bacterial strains and the slowdown in the development of new antibiotics. Phages, unlike antibiotics, target specific bacterial strains, reducing the impact on the natural microbiota and potentially offering a …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 31–35 Read article
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Bio-Inspired Membranes in Oral Drug Delivery: A Pathway to Enhanced Permeability and Targeted Therapy
Abstract: Bio-inspired membranes in oral drug delivery represent a significant advancement in pharmaceutical technology, harnessing principles of natural biological systems to improve drug permeability, bioavailability, and targeted release. This review discusses the design, materials, and fabrication techniques used in bio-inspired membranes, with a focus on materials like chitosan, silk fibroin, and synthetic polymers that mimic biological structures. By exploring the mechanisms of drug permeation, such as mucoadhesion and selective permeability, bio-inspired …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 39–52 Read article
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Evaluation of Polysaccharide-Based Membranes for Transdermal Drug Delivery in Chronic Pain Management
Abstract: In order to improve treatment effectiveness and patient compliance, chronic pain management is still a major challenge in modern healthcare, requiring creative medication delivery methods. The potential of polysaccharide-based membranes for transdermal drug delivery is assessed in this work, with particular attention to chitosan, alginate, and hydroxypropyl methylcellulose (HPMC). Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) were two characterization techniques used to assess the membranes' physical and chemical …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 28–38 Read article
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Design and Development of Novel Floating Drug Delivery Systems
Abstract: Recent advances in science and technology have greatly aided in the creation of novel drug delivery methods, especially in addressing physiological issues including irregular stomach emptying times and brief stomach residence periods. Long-term stomach absorption is the goal of gastro-retentive dosage forms (GRDF). Floating drug delivery systems, expanding or swelling systems, polymer-based bioadhesive systems, high-density systems, and other ways that postpone stomach emptying are just a few of the techniques …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 1–22 Read article
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Innovative Approaches in Bioinspired and Biomimetic Membrane Technologies: Bridging Nature and Engineering
Abstract: Bioinspired and biomimetic membranes represent a ground breaking advancement in membrane technology, offering innovative solutions to critical global challenges in water purification, chemical separation, and energy conversion. These membranes leverage the exceptional transport properties of biological systems, particularly through the incorporation of aquaporin proteins, which facilitate rapid and selective water transport. This review synthesises recent developments in aquaporin-based membranes, highlighting their remarkable efficiency in desalination processes, where they serve as …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 53–60 Read article
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Food Processing and Membrane Technologies: Food Industry and Microfiltration
Abstract: Membrane technologies are being used extensively in food processing because they improve the process efficiency as well quality of end product. Microfiltration is one of these most important process in food and beverage industry for separation and purification. Along with a unique pressure driven separation process, microfiltration membranes provide the removal of suspended solids, bacteria and colloids from your product while preserving valuable nutrients and flavors. Microfiltration is extensively used …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 23–27 Read article
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Practical studies in Vero cell and Human amnion cells for viral and stem cell applications
Abstract: Vero cells are one of the most popular mammalian continuous cells in molecular, cellular, and microbiological research. African green monkey kidneys are used to make these.One continuous cell line is the Vero cell line. This cell line is dependent on anchorage. Vero cells can be cultured in suspension because they are anchorage independent. Thought to be non-tumorigenic cells that came from a female Chlorocebus sabaeus Numerous viruses can infect vero …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 1–8 Read article