STM Journals Peer-reviewed research from Consortium e-Learning Network

Research and Reviews: A Journal of Pharmacology

In vitro Antioxidant Activity of Calotropis Procera

  1. S Priya
  2. S Jennifer

Abstract

Antioxidant activity of root of Calotropis procera extract was evaluated in a series of in vitro assay involving free radicals. IC50 values were determined. Extracts of I. coccinea exhibited scavenging effect in concentration dependent manner in all in vitro method. IC50 of ethyl acetate extract was 48.43, 75.811 and 60.60 μg/ml for 2,2-diphenylpicrylhydrazyl radical scavenging, hydrogen peroxide scavenging, and nitric oxide scavenging, respectively. Ethyl acetate extract shows good in vitro antioxidant activity compared to other extract.   Keywords: Calotropis procera, DPPH free radical, nitric oxide radical, hydrogen peroxide scavenging

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