The objective of the present work is to develop a new, rapid, simple, economical, precise, sensitive, linear and accurate, UV Spectrophotometric method has been developed. Phosphate buffer of pH 6.8 is used as solvent for the estimation of Brisoprolol Fumerate bulk and pharmaceutical formulation as per ICH guidelines. Spiked Brisoprolol Fumerate was checked over UV-visible extend for its wavelength of greatest absorbance. The wavelength of most extreme absorbance for Brisoprolol Fumerate was found to be 223nm. The relationship coefficient over the concentration extends of 10–50 µg/ml was found to be 0.997. The accuracy was carried out as per recovery study and found between 99.65%% to 100.45%The LOD and LOQ of Brisoprolol Fumerate was found to be 0.283 and 0.858 respectively. The method was successfully applied to estimate Brisoprolol Fumerate in prepared formulation and result were in good agreement with claims. Depending on the results, the given method can be successfully applied in estimation of Brisoprolol Fumerate.
