Research and Reviews: A Journal of Pharmacology
Volume 8, Issue 2 (2018)
Published
Table of contents
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5-Lipoxygenase and Phospholipase A2 Inhibitory Potentials of Alcoholic Extract of Cyperus rotundus: In vitro and In silico Study
Abstract: The literature revealed that not much reports are known for the anti-inflammatory activity of any Cyperus rotundus plant part (or extract) with respect to the molecular targets (inflammatory mediators) like cyclooxygenase-1/2 (COX-1/2), 5-lipoxygenase (5-LOX), and phospholipase A2 (pLA2). The present investigation involved exploration of in vitro inhibitory potential of alcoholic extract of C. rotundus rhizome against two important inflammatory mediators; 5-LOX and (porcine) pLA2. In addition to it, the role …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 2, 2018 · pp. 1–5 Read article
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A Study of Symptomatic Remission and its Association with Nicotine Dependence and Degree of Disability in Patients of Schizophrenia
Abstract: Schizophrenia is a typically disabling disease that impacts negatively on the academic, occupational, social and family functioning of the patients and becomes the considerable cause of illness-related disability. This study aimed to examine the association between remission; tobacco dependence and degree of disability in schizophrenic patients. A total of 318 consecutive patients of >2 years of illness were recruited at the Psychiatry Department of a Tertiary Care Hospital. Sociodemographic, clinical …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 2, 2018 · pp. 10–18 Read article
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Prescribing Pattern of Nonsteroidal Anti-inflammatory Drugs among the Specialists Doctors in Mymensingh City of Bangladesh—A Descriptive Study
Abstract: Irrational prescribing of medicines is a global problem, particularly in developing and transitional countries like Bangladesh, and so drug use patterns need to be evaluated. The aim of the study was to investigate the prescribing patterns of nonsteroidal anti-inflammatory drugs (NSAIDs) among the specialist doctors in Mymensingh city of Bangladesh. Prescriptions were collected from patients visiting different hospitals and pharmacies in different areas of Mymensingh city. A total number of …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 2, 2018 · pp. 19–23 Read article
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Sexual Dysfunction Among Male Schizophrenics: A Comparison Between Psychotropic Medicines Treated and Treatment Naïve Patients
Abstract: Introduction: The prevalence of sexual dysfunction (SD) is higher in persons with mental disorders, particularly those treated with psychotropic medication. There are very few studies, especially in the Indian population, addressing the frequency of SD due to psychotropic medications. SD in schizophrenia may be a consequence of many factors; the condition itself, its socioeconomic impact and its treatment. Method: This cross-sectional study was conducted in the psychiatric unit of a …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 2, 2018 · pp. 24–30 Read article
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Evaluation for Diuretic Activity of Cassia auriculata
Abstract: The present study has been designed to elucidate the pharmacological activities like analgesic, anti-inflammatory and diuretic activities of flowers of Cassia auriculata on albino mice and rats. The doses for pharmacological activities was fixed petroleum ether, methanol and aqueous extracts was 500 mg/kg b.w. respectively. Analgesic activity was carried out by Eddy’s hot plate method. In this model, nociceptive reaction toward thermal stimuli in mice is a well validated model …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 2, 2018 · pp. 6–9 Read article