Research and Reviews: A Journal of Pharmacology
Volume 8, Issue 1 (2018)
Published
Table of contents
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A Review: Uses of Thalidomide in Cancer Treatment
Abstract: Thalidomide is an anti-angiogenetic agent, which was widely used in early 1950s and 1960s for the treatment of morning sickness in pregnant women. The drug has been banned in1960 as it caused severe birth defects in children whose mothers had used thalidomide during pregnancy. Though it caused severe adverse effects the drug has found to be effective in the treatment of leprosy and multiple myeloma. These days thalidomide has been …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 1, 2018 · pp. 1–5 Read article
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Chemical Constituents and Tyrosinase Inhibitory Activity of Ethyl Acetate Extract of the Leaves of Morus alba L. from Vietnam
Abstract: AbstractFour compounds (DB1–4) were isolated from the Mulberry leaves (Morus alba L.) collected in Thai Nguyen province by chromatographic methods. These compounds were identified as: Kaempferol-3-O-β-D-glucopyranoside (DB1), quercetin 3-O-α-L-rhamnopyranoside (DB2), isofraxidin-7-O-β -D-glucopyranoside (DB3), and (±) -3, 5, 6, 7, 8, 4’-hexahydroxyflavane (DB4). Their structures were elucidated by spectroscopic methods, including mass spectrometry (MS) and nuclear magnetic resonance (NMR). Compound DB4 was isolated from Mulberry leaves for the first time. Compound …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 1, 2018 · pp. 21–26 Read article
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A Study on Safety and Efficacy of Newer Anti-diabetic Drugs (Sitagliptin, Vildagliptin) in Type 2 Diabetes mellitus
Abstract: AbstractType 2 diabetes mellitus accounts for as much as 90% of all cases of diabetes mellitus. India leads the world with largest number of diabetes subjects earning the dubious distinction of being term the “Diabetes Capital of the world”. The present study was aimed to evaluate safe and effective management of type 2 diabetes mellitus patients by using newer anti-diabetic drugs. A total of 81 patients were interviewed; out of …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 1, 2018 · pp. 27–30 Read article
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Evaluation for Analgesic and Antipyretic Activities of Celosia argentea
Abstract: In the present study, we have evaluated different extracts of Celosia argentea seeds for analgesic and antipyretic activities using different models of pain and rectal temperature. The analgesic activity of Celosia argentea was carried out using eddy’s hot plate method in mice. The antipyretic activity was carried out using yeast induced pyrexia in rats. The three different extracts (Ext I: Pet ether, Ext II: Ethanol, Ext III: Aqueous) of Celosia …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 1, 2018 · pp. 31–34 Read article
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Ethnomedicinal, Pharmacological and Phytochemical Screening of Supari (Areca catechu Linn.): A Review
Abstract: Supari (Areca catechu Linn.) is a tall tree about 10–20 m long. It is used both locally and internally. Local application is beneficial in various acute inflammatory conditions in the form of gargle, vaginal douche or abzan, decoction, juice and oil. Internally it act as muqavvie-qalb (cardiotonic) and muqavvi-e-ama (intestinal tonic), sozish meda (gastric irritation), dries the excessive secretions of mouth, used in vomiting and nausea, strengthen the teeth and …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 1, 2018 · pp. 6–20 Read article