Research & Reviews: A Journal of Drug Formulation, Development and Production
Volume 9, Issue 3 (2022)
Published
Table of contents
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A Study and Report on Role And Impact Of Clinical Pharmacist in assessment of Prescribing Cascades In Antibiotics Usage For Infectious Diseases in Promotion of Rational Drug Usage
Abstract: ABSTRACT:A Prescription cascade occur when the healthcare providers fail to recognise that the new symptoms are actually the side effects of the medications under treatment. The study was based on the role and impact of clinical pharmacist in assessment of prescribing cascades in antibiotics usage for infectious diseases in department of general medicines and paediatric department at ESI hospital, Indiranagar, Bangalore, Karnataka, India. The main motto of the study was …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 3, 2022 · pp. 1–14 Read article
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Development and Characterization of Ondansetron containing Chewing Gum Formulations for Preventing Vomiting and Motion Sickness
Abstract: AbstractChewing gums are portable drug delivery devices that can deliver medications via the buccal route for either local or systemic absorption. Without water, it can be administered discretely. Antiemetic medication is combined with the gum base in medicated chewing gums, which are chewed rather than ingested. These formulations contain Ondansetron, Polyvinyl alcohol, Carboxymethyl agorase, Peppermint oil, Polyethylene glycol (PEG-400), Calcium carbonate, Synthetic gum base, Propyl paraben, and Ascorbic acid. The …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 3, 2022 · pp. 15–28 Read article
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A Review on Wound Healing: Pathophysiology, Animal Model and Role of Biomarkers
Abstract: AbstractBlood cells, extracellular matrix, parenchyma cells, and soluble mediators are all involved in the physiological process of wound healing, which is highly complex, dynamic, interactive, and well-regulated. The 4 stages of wound healing are separated out. Hemostasis b. Inflammation c. Proliferation d. Remodeling. Many animal models are employed in the examination of wound healing activities because a large variety of models have been produced for examining different components of the …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 3, 2022 · pp. 29–39 Read article
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Anti-tuberculosis Effects of the Extracts from Humulus japonicus and Humulus lupulus in in vitro and ex-vivo TB Models
Abstract: AbstractObjectives: Anti-tuberculosis effects of Humulus japonicus and Humulus lupulus were evaluated in in vitro direct killing ability and in ex-vivo indirect killing ability through human macrophages. Methods: H37Rv or XDR strain or NTM was treated with Crude extracts of Humulus japonicas and Humulus lupulus to estimate the MIC(Minimal Inhibitory Concentration) or MKC(Minimal Killing Concentration). Results: The MIC or MKC of the extracts of Humulus japonicus was 31.2 µg/ml for H37Rv …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 3, 2022 · pp. 40–49 Read article
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Ligand Efficiency in Relation to 3D Physicochemical Characters of Novel HIV-1 Vif Antagonist: An Approach in The Optimization of HIV Drugs
Abstract: AbstractLigand efficiency is a design framework commonly used in drug discovery. Thirty-six (36) newly discovered 1,2,3-triazole analogues as potent new inhibitors of HIV-1 Vif were subjected to quantitative structure-property relationship (QSPR) modeling to predict their ligand efficiencies (LE) in an attempt to improve/optimize it by using some numerical data of HIV-1 Vif inhibitors based on their physical and chemical properties (descriptors). Various 3D physicochemical properties or descriptors were calculated from …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 3, 2022 · pp. 50–59 Read article