Research and Reviews : Journal of Computational Biology
Volume 8, Issue 3 (2019)
Published
Table of contents
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Ushering Era of Nanomedicines: A Short Review
Abstract: Nanomedicine is a revolutionary field of nanotechnology and it is extending very rapidly with every passing day. This field is focusing on the developing of the nanoparticles for the diagnosing and treatment of patient’s diseases. It is also in the field of therapeutic and prophylactic applications. Nanoparticles have unique properties that we used in medicines for the treatment. Nanomedicines prefer over other medicines because of the extraordinary properties of nanoparticles …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 3, 2019 · pp. 1–8 Read article
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Drug and Non-drug Treatment Options of Fibromyalgia
Abstract: Fibromyalgia (FM) treatment does not have a clear objective pathophysiological therapeutic goal. The management of this complex condition has thus perplexed the medical community for many years, and several national and international guidelines have aimed to address this complexity. Pain relieving pharmaceutical medications are generally connected with an assortment of unfriendly reactions, for example, constipation, urinary retention, nausea, sedation, respiratory depression, myoclonus, delirium, sexual dysfunction, and hyperalgesia. The challenge of …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 3, 2019 · pp. 15–23 Read article
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A Short Review on Role of Nanotechnology in Daily Life
Abstract: Nanotechnology is latest technology of 21st century. It has impacts on each field of life. Below mentioned are various fields in which this technology is playing its positive role. Nanotechnology is predicted to change medicinal services by filling in as a novel technique for disease analysis as well as prevention, quality treatment, drug delivery plus gene therapy. In nanoelectronics, the look for a successor to Complementary metal–oxide–semiconductor (CMOS) innovation is …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 3, 2019 · pp. 24–33 Read article
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Development of vaccine against Helicobacter pylori using Bioinformatics approaches
Abstract: Helicobacter pylori (H. pylori) are a widespread kind of bacteria which flourish in the digestive tract and have a propensity to damage the stomach lining. The microbe infects around 60% of the adults globally. H. pylori infections are responsible for most of stomach and small intestine ulcers. Using Bioinformatics approaches, we have identified certain proteins that possess the resistance, essentiality and virulence factors for this pathogen. Computational tools and servers …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 3, 2019 · pp. 34–68 Read article
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In Silico Molecular Docking Studies of Phytoconstituents Identified in Curcuma zedoaria Rosc. on Acetylcholinesterase: An Enzyme Target for Anti Alzheimer’s Activity
Abstract: Alzheimer’s disease (AD) is a chronic, progressive and disabling organic brain disorder characterized by disturbances of multiple cortical functions. Acetylcholinesterase (AChE) inhibition is thought to be a promising approach towards the treatment of AD. The aim and objective of the present study is to perform in-silico docking analysis of the major active constituents identified in Curcuma zedoaria Rosc. against AChE for anti-Alzheimer’s activity. In this perspective, phytoconstituents like bisdemethoxy curcumin, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 3, 2019 · pp. 9–14 Read article