Research and Reviews : Journal of Computational Biology
Volume 8, Issue 1 (2019)
Published
Table of contents
-
In silico Prediction of Two New Conformations of Aβ42 Peptide and Possible Mechanism of Their Aggregation
Abstract: Alzheimer’s disease is one of the most studied neurodegenerative diseases. The cause for most cases of this disease is unknown. However, there are many hypotheses regarding the progression of this disease. One of the hypotheses is the amyloid hypothesis. Amyloid precursor protein present on chromosome 21 is cleaved by β and γ sectretases. The cleaved fragments of this protein, nearly 36–43 residues long aggregates and are deposited as plaque in …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 1, 2019 · pp. 1–7 Read article
-
A Review on Zinc Oxide Nanoparticles Based on Photocatalytic Activity
Abstract: The Zinc Oxide (ZnO) is a photocatalyst which is available for photoreaction system by using the metal oxide (MO) degradation present ultraviolet irradiation at high temperature. The removal rate of metal oxide (MO) was observed in zinc oxide has been reached up to 99.73, 99.29 and 99.70%. The composite ratio was increased from 2:1 to 4:1 after 30 minutes and continuously this ratio was also increased up to 5:1. Hence …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 1, 2019 · pp. 13–25 Read article
-
Anti-hyperglycaemic Effect of Psidium guajava Extracts in Diabetes Mellitus: Systematic Review and Meta-analysis
Abstract: Introduction: Psidium guajava belonging to family Myrtaceae is traditionally used plant for the treatment of diabetes in many countries of the world. This systematic review was designed to determine level of evidence of on the anti-hyperglycaemic effect of Psidium guajava extracts from experimental trials. Methods: An electronic literature search from the database inception was performed since December 2014 with specified terms and defined outcome. We included only experimental study designs …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 1, 2019 · pp. 26–33 Read article
-
Square Shape CPW Antenna for Breast Cancer Detection
Abstract: In this study, a antenna design is proposed to detect the breast cancer tissues by using microwave imaging based on the contrast in electrical properties of healthy fatty Breast tissues. The designed antenna is affordable as a primary health observation and has no health risk. A highly directive flexible structure is presented for microwave imaging which can be used in clinical diagnosis. To detect the tumour in a breast phantom, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 1, 2019 · pp. 34–38 Read article
-
Hydroxylated Chalcone Derivatives as Future Aldose Reductase Inhibitors: Discovery through Docking Technique
Abstract: The research endeavors molecular docking assisted exploration of ALR inhibitory perspectives of some B-ring substituted hydroxyl group (A-ring) containing chalcone compounds against human aldose reductase in complex with NADP+ and the inhibitor IDD594 (PDB ID: 1US0) by utilizing the iGEMDOCK (Genetic Evolutionary Method for Molecular Docking) software. The present investigation immensely focused on the human aldose reductase inhibitory perspectives of some hydroxylated chalcone compounds. The inhibition of the enzyme by …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 1, 2019 · pp. 8–12 Read article