Research and Reviews : A Journal of Biotechnology
Volume 16, Issue 1 (2026)
Table of contents
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Lab Reagents and Their Importance in Bio-chemistry
Abstract: Biochemical reagents are essential substances in the study of life at the molecular level. These reagents help scientists detect, identify, and quantify bio-molecules such as proteins, carbohydrates, nucleic acids, and enzymes in biological systems. They play a vital role in understanding metabolic reactions and physiological processes within living organisms. Biochemical reagents are generally classified into analytical, diagnostic, enzymatic, chromogenic, and buffer reagents, each serving a specific purpose in laboratory and …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Application of Priestia Megaterium in the Bioremediation of Petroleum Hydrocarbon Contaminated Environments
Abstract: Petroleum pollutants pose a serious and persistent threat to environmental ecosystems, particularly affecting soil and water quality. Effective and sustainable remediation strategies are crucial to mitigate their impact and safeguard environmental health. In this context, bioremediation—using microorganisms to degrade harmful contaminant —emerges as a promising and eco-friendly approach. The present study explores the biodegradation capabilities of the bacterium Priestia megaterium, a species previously recognized for its ability to break down …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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A Comprehensive Review on Mentha arvensis Species
Abstract: Mentha arvensis L., often referred to as field mint or wild mint, is a fragrant medicinal herb in the Lamiaceae family and is extensively found in temperate and subtropical areas. The plant is appreciated for its essential oil, notably high in menthol, which adds to its unique scent and extensive medicinal possibilities. Historically, M. arvensis has been utilized in several medical systems for addressing digestive issues, respiratory problems, headaches, and …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Innovations in Gene Therapy: Revolutionizing Treatment for Genetic Disorders and Diseases
Abstract: Gene therapy is a revolutionary intervention in the treatment of genetic diseases since it is an intervention that aims at the very source of diseases, through editing and modification of genes. More recent innovations in gene editing systems, such as CRISPR-Cas9, CRISPR-Cas12, and prime editing, have greatly increased the accuracy and effectiveness of gene therapies, enabling more specific therapies. The opportunities of personalized medicine are also extended by the creation …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Engineering Anti-Tau Monoclonal Antibodies for Alzheimer’s Disease and Parkinsonian Tauopathies: A Biotechnological Perspective
Abstract: Neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease are characterized by progressive neuronal loss associated with abnormal protein aggregation. Among these, tauopathies are defined by the accumulation of hyperphosphorylated tau protein, which plays a central role in disease progression. Advances in biotechnology have enabled the development of anti-tau monoclonal antibodies (mAbs) as promising therapeutic agents aimed at neutralizing pathological tau species and inhibiting their propagation. This review provides a …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Metagenome-Informed Engineering of Monoclonal Antibodies: Mining Microbial Immunoglobulin-Like Domains for Ultra-Stable Therapeutics
Abstract: Metagenome-informed engineering represents an emerging strategy for improving the stability and functionality of monoclonal antibodies (mAbs) by leveraging the vast diversity of microbial immunoglobulin-like (Ig-like) domains (10,24). These domains, derived from uncultured bacteria and bacteriophages, exhibit exceptional thermostability, protease resistance, and structural resilience due to adaptation to extreme environments (29,30). This review highlights advances in metagenomic mining, structural characterization, and protein engineering that enable the integration of microbial Ig-like scaffolds …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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The Future is Bioengineered: Consequences, Directions, and Regulation
Abstract: Biotechnology is changing how people interact with health, life, and the environment very quickly. This article talks about how new tools in genetic engineering, synthetic biology, and bioinformatics are making it possible for scientists to build and change biological things with more accuracy than ever before. Biotechnology is changing several fields, from making personalised medical treatments and disease-resistant crops to making biofuels and materials that break down naturally. The talk …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Bacteria on Salt Water Medium Evaluation: The Conceptual Impacts of Temperature
Abstract: The potential impact of temperature on bacteria on salt water medium for crude oil degradation in an aerated lagoon system was simulated using MATLAB Simulation software. The specific rate of bacteria obtained revealed maximum at temperature of less than 35oC with the order of 90 o C (11 cfu/ml) > 60 o C (40 cfu/ml) > 45 o C (35 cfu/ml) > 30 o C (28 cfu/ml). Most of the …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Recombinant Proteins and Nested Gene Regulation: Nutrient Driven Immune Response and Disease Resistance in Livestock
Abstract: Livestock production systems are increasingly challenged by infectious diseases, metabolic disorders, and environmental stressors that reduce productivity and compromise animal health. Advances in molecular biology and animal nutrition now offer new opportunities to strengthen disease resistance through integrated strategies that combine recombinant protein technologies, gene regulatory mechanisms, and nutrient mediated immune modulation. This review examines how recombinant proteins and nested gene regulation interact to shape nutrient driven immune responses in …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Enhancing Rhizoremediation of Petroleum Hydrocarbon-Contaminated Soil Using Brachiaria ramosa: A Review of Plant Growth Promotion and Degradation Potential
Abstract: This paper examines rhizoremediation as a sustainable and environmentally acceptable remediation technique in response to the growing problem of petroleum hydrocarbon pollution in soils. Brachiaria ramosa, a tropical grass species that may be useful in contaminated settings, is the main emphasis. A critical analysis of the literature on plant growth-promoting rhizobacteria (PGPR), microbial consortia involved in hydrocarbon breakdown, and rhizosphere-mediated degradation is conducted. There is a thorough discussion of important …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 · pp. 24–41 Read article