Research & Reviews: A Journal of Bioinformatics
Volume 4, Issue 3 (2017)
Published
Table of contents
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Cancer biology and Sequencing technology: A new era for personalized patient care.
Abstract: Cancer is one of the most deadly diseases causing high mortality around the world. Lot of efforts are being made to be able to device a proper treatment for cancers. The majority treatments for various types of cancers comprise of surgery, radiation, chemotherapy, hormone therapy, immune therapy, and targeted therapy. These methods of treatment may not be fully able to get rid of cancer but able to extend the life …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 4, Issue 3, 2017 · pp. 1–14 Read article
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Selection of Bio-implant Materials using Entropy and Analytic Hierarchy Process
Abstract: Biomaterials are artificial or natural materials that replace the diseased or damaged organic systems to improve the durability and quality of human life and provide a pain-free life for patients with a range of motions adequate for daily activities. These materials must be mechanically strong and must be amicable to human body. To ensure mechanical behaviour properties such as tensile strength, yield strength, fatigue strength and wear resistance must be …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 4, Issue 3, 2017 · pp. 15–21 Read article
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Biochemical and Structural Characterization of Helicobacter pylori Peptide deformylase by Computational Methods
Abstract: Helicobacter pylorus is classified as class one carcinogen in causing gastric cancer. Peptide deformylases (PDFs) present in bacteria removes the formyl group from the N-terminal Methionine of newly synthesized proteins which is necessary in protein maturation. These enzymes have shown as new targets in antibacterial, antimalarial and anticancer drug discovery. Here an insilico technique was initiated to characterize structural and biochemical properties of this protein. Pair wise sequence alignment with …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 4, Issue 3, 2017 · pp. 22–28 Read article
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A Study to Assess the Effectiveness of Information Booklet Regarding DOTS Therapy among the Tuberculosis Clients in a Selected Primary Health Centre
Abstract: The purpose of the study was to assess the effectiveness of information booklet regarding DOTS therapy among the tuberculosis clients in a selected primary health centre. The design used for this study was quasi experimental one group pre-test without control group with evaluative approach. Simple random sampling technique was used to select the sample for the study. The data were collected by using structured questionnaire from 60 tuberculosis clients before …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 4, Issue 3, 2017 · pp. 29–33 Read article
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Study of Personalized Medicine and Behavior of different Marketed Drugs of CML
Abstract: Personalized medicine is rapidly developing practice of medicine that uses an individual's genetic profile to guide decisions made in regard to the prevention, diagnosis, and treatment of disease. CML (Chronic Myeloid Leukemia) is characterized by a Philadelphia chromosome resulting from a reciprocal translocation between chromosomes 9 and 22, containing a chimeric gene called BCR-ABL. Management of patients with chronic myeloid leukemia has become increasingly difficult over the last few years …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 4, Issue 3, 2017 · pp. 34–38 Read article