8 publications

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    A narrative review on cardiovascular disease due to the role of deficiency of Vitamin D and its management

    Abstract: Cardiovascular disease is the prevalent cause of morbidity and mortality in the world, affecting many millions of individuals every year. Atherosclerosis, a chronic inflammatory condition that involves different cell types, several cytokines and adhesion molecules, is the underlying cause of cardiovascular disease. Vitamin D plays a pivotal role in bone homeostasis and calcium metabolism. Though, current research has specified additional helpful effects of vitamin D on the cardiovascular system. Vitamin …

    Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 2, 2021 · pp. 9–20 Read article

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    Thrombotic thrombocytopenic purpura: A Narrative Review of Diagnosis and Treatment by drugs and novel agents.

    Abstract: Thrombotic thrombocytopenic purpura (TTP) is an infrequent but fatal disease, is primarily caused by autoantibodies against the von Willebrand factor (VWF) cleaving metalloprotease ADAMTS13. Overall, severe deficiency of plasma ADAMTS13 action (< 10 IU dL-1) with or without noticeable inhibitory autoantibodies counter to ADAMTS13 supports the diagnosis of TTP. The International Working Group for TTP released a consensus statement on the standardization of terminology in these disorders which we use …

    Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 10, Issue 1, 2021 · pp. 40–55 Read article

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    An Overview on Resistant Hypertension: Pathophysiology, Diagnosis, and Management

    Abstract: Hypertension is a universal health issue, which is an utmost attributor for the weight of cardiovascular diseases when BP leftovers resistant or stubborn to therapeutic events. Notwithstanding the progressive growth in the antihypertensive therapy, the incidence of resistant hypertension is assessed to be less than 5% of the hypertensive inhabitants. Resistant hypertension is well-defined as blood pressure that leftovers over head the goal line in meanness of the simultaneous usage …

    Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 10, Issue 1, 2021 · pp. 16–30 Read article

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    An overview on the diagnosis and approaches in pharmacological management of Parkinson’s disease

    Abstract: Parkinson’s disease (PD) might be a mutual neurodegenerative disease considered by a movement disorder containing rest tremor, bradykinesia, rigidity, and postural instability, and second-leading reason of dementia and is categorized by an advanced loss of dopaminergic neurons within the neural structure alongside the occurrence of intraneuronal α-synuclein-positive enclosures. PD is identified where bradykinesia happens along with rigidity or tremor within the existence of supporting features. The diagnosis is clinical, and …

    Published in Research and Reviews: A Journal of Neuroscience · Vol. 11, Issue 1, 2021 · pp. 1–8 Read article

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    Acute Ischemic Stroke: Diagnosis and Management Approach

    Abstract: Stroke is the next chief reason of death worldwide and the foremost reason of debility, with a growing occurrence in emerging countries. Ischemic stroke produced by arterial obstruction is accountable for the majority of strokes. Management focuses on fast reperfusion with endovascular thrombectomy and intravenous thrombolysis, which together decreases debility but are time grave. The important primary stage in stroke maintenance is initial identification of patients with stroke and triage …

    Published in Research and Reviews: A Journal of Neuroscience · Vol. 10, Issue 3, 2020 · pp. 25–46 Read article

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    An Overview on the Management cum Treatment of Nephropathy in Type-1 Diabetes Mellitus

    Abstract: The motive of this review is to keep updated with the medical nonfictions, the projected early natural arrangement of diabetic nephropathy, the theories behind the root of its pathogenesis pathophysiology, diagnosis and its supervision. Type 1 diabetes is an autoimmune disease characterized by advanced destruction of pancreatic beta cells by genetic and environmental factors which primes to an absolute necessity of insulin for survival and conservation of health; while Diabetic …

    Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 3, 2020 · pp. 19–38 Read article

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    Maternal and Fetal Consequences of Vitamin D Deficiency during Pregnancy: An Overview

    Abstract: Apprehensions exist about the adequacy of vitamin D in pregnant and lactating women. Maternal vitamin D status influences maternal, fetal, and breast-fed infant bone health; maternal adverse outcomes (bone health, gestational diabetes, obstructed labor, preeclampsia, and infectious disease); fetal adverse outcomes (growth, bone health, gestational age, intrauterine growth, type 1 diabetes, asthma, immune development and cardiac disease); and infant adverse outcomes. Throughout pregnancy, maternal vitamin D standing may be of …

    Published in Research and Reviews: A Journal of Medicine · Vol. 10, Issue 3, 2020 · pp. 12–28 Read article

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    An Insight to Hyponatremia in Cirrhosis: Pathophysiology and Management Approaches

    Abstract: Cirrhosis is considered by systemic and splanchnic vasodilation that principals to extreme nonosmotic excretion of vasopressin. Hyponatremia is a mutual electrolyte irregularity in progressive liver disease that outcomes from the diminished capability of the kidney to excrete solute-free water that principals to “dilutional” hyponatremia water retention uneven to the retaining of sodium. Hyponatremia is mutual in cirrhosis. It frequently happens in a progressive phase of the disease and is related …

    Published in Research and Reviews : A Journal of Immunology · Vol. 10, Issue 3, 2020 · pp. 30–46 Read article

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