Stability-indicating method

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• Published Subscription Review Article 17 Jan 2026

  Stability-Indicating Rp-Hplc Development and Validation for the Estimation of Lercanidipine Hydrochloride Content in Tablet Dosage Form

  By Ratnakar Tripathi, Bhushan Korde, Sunil Kumar Shah, B.K. Dubey, Deepak Kumar Basedia

  Abstract: A sensitive, stability-revealing, and easy reverse-phase high-performance liquid chromatographic (RP-HPLC) technique was developed and rationalized to be in a position to determine Lercanidipine hydrochloride in ingested dosing preparations. It was separated by chromatography on a C 18 column using a mobile phase containing 10 mM potassium dihydrogen phosphate buffer and methanol (20:80, v/v; pH 4.0) at a flow rate of 1.0 mL/min and UV detected at 258 nm. The retention …

  Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 17–26 Read article →