SPECT/CT

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• Published Subscription Original Research 19 May 2025

  MIRDcalc & OLINDA/EXM Dosimetry Software Analysis by SPECT/CT Scan Data of Lu-177 DOTATATE Radionuclide Therapy of NET Patients

  By Madhulika Mehrotra Mehrotra, Prashant Mishra, Saurabh Sharma, Preethi Deenadayalan

  Abstract: Accurate dosimetry is essential in nuclear medicine for optimizing radionuclide therapies and ensuring patient safety. In Radiopharmaceutical dosimetry the Medical Internal Radiation Dosimetry (MIRD)Society is the pioneer in organ-level dosimetry providing the fundamental basis for commonly used clinical and research dosimetry software like MIRDOSE and OLINDA/EXM. Recently, in MIRD Pamphlet No. 28, Part 1, the MIRD committee of the Society of Nuclear Medicine and Medical Imaging presented a new Software …

  Published in Journal of Nuclear Engineering & Technology · Vol. 15, Issue 2, 2025 · pp. 48–63 Read article →

• Published Open access Original Research 21 Aug 2023

  Activity Quantification of Lu-177 SPECT/CT Imaging for Calibration Factor Analysis in Clinical Radionuclide Dosimetry

  By Madhulika Mehrotra, Sanjana Ballal, Prashant Mishra, C.S. Bal

  Abstract: Purpose: To evaluate the calibration factor (CF) at three-time points with the same protocol & acquisition parameters for the images of Lu-177 activity, scanned by two different SPECT/CTs (GE & MEDISO) using a cylindrical Jaszczak phantom with cold inserts, filled with uniform activity in water and to analyze the changes in the calibration factor data with time. The purpose of the study is to quantitatively analyze the first step (calibration …

  Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 2, 2024 · pp. 9–22 Read article →