Polymeric Nanocomposites

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• Published Subscription Original Research 16 Jun 2026

  Design and Evaluation of Thermo-Responsive Poly(N-isopropylacrylamide)-Based Polymeric Nanoparticles for Temperature-Triggered Intratumoral Release of Doxorubicin in Solid Tumors

  By Kavya D, Khanderao Rajaram Jadhav, Suvarna Manoj Bhadane, Sujit Appasaheb Jadhav, Mohit Kumar, Manisha S Nangude, Josef Yakin, Vikrant Kisanrao Nikam, Akshay Kumar K S

  Abstract: Thermo-responsive polymeric systems have emerged as promising platforms for targeted intratumoral drug delivery in cancer therapy. This study aimed to develop and evaluate poly(N-isopropylacrylamide) (PNIPAM)-based polymeric nanoparticles as intelligent carriers for temperature-responsive delivery of doxorubicin (DOX) to solid tumors. Nanoparticles were synthesized via free radical polymerization using N-isopropylacrylamide as a thermoresponsive monomer and N,N′-methylenebisacrylamide as a crosslinker, forming a stable network with a tunable lower critical solution temperature (LCST).The optimized …

  Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 159–168 Read article →

• Published Subscription Review Article Special issue 20 Jan 2026

  Polymer Nanocomposites As Emerging Platforms in Pharmaceutical Nanotechnology

  By Lakshman Kumar Dogiparthi, Balakrishna Talamanchi, Mynam Harika, Vannappagari Prabhash, Raichur Ruhinaz, Kora Keerthi, A. Jayanth, P. Amitha, Bezawada Siva Nagaraju, Guggulotu Vishnu Tulasi Naik

  Abstract: Nanotechnology allows the handling of materials in the 1–100 nm range, where distinct physicochemical phenomena, including quantum effects and higher surface-to-volume ratio, enable disruptive uses in pharmaceuticals and biomedicine. Significant challenges in solubility, stability and targeted biodistribution of therapeutics can be overcome by incorporating nanostructured polymers and polymer-based composites into drug delivery systems. PLGA nanoparticle and other nanocarriers, such as PLGA micelles, dendrimers, and hydrogels, have revealed promising effects on …

  Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 268–278 Read article →