Oral thin film
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Formulation, Development and Evaluation of Oral Thin Film of Metoclopramide Hydrochloride
Abstract: Metoclopramide Hydrochloride, an anti-emetic drug is indicated for the patients with diabetic gastroparesis and Gastro Esophageal Reflux Disease (GERD). It is difficult for a patient to swallow a tablet during emesis. So, an attempt was made to develop a patient-friendly orally dissolving film using clove oil and menthol as flavoring agents, aspartame as sweetener, polyvinyl alcohol and glycerol as film forming agent and plasticizer respectively. Based on appearance and palatability …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 2, Issue 2, 2011 Read article