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A Comprehensive Review on Premature Hair Graying: Factor Contributing, Pathogenesis, Prevention Strategies, and Natural Therapeutic
Abstract: Premature graying of hair (PGH), also known as early canities, is an increasingly common dermatological concern characterized by the loss of natural hair pigmentation before the expected age. Hair color is primarily determined by the quantity and type of melanin synthesized by melanocytes within the hair follicle. Disruption in melanocyte function, survival, or melanin synthesis leads to hair graying. Multiple intrinsic and extrinsic factors contribute to PGH, including genetic predisposition, …
Published in Research and Reviews: A Journal of Health Professions · Vol. 16, Issue 1, 2026 · pp. 13–20 Read article