Malaria
6 articles · search the full text for this term
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The Parasitic Fingerprint: Tracing Infection to Host Illness
Abstract: Parasitic infections remain a major global health burden, causing significant morbidity and mortality, particularly in tropical and subtropical regions. A critical aspect of disease pathogenesis is the unique molecular and cellular imprint left by parasites in their hosts, termed the “parasitic fingerprint.” These fingerprints encompass parasite-derived proteins, nucleic acids, metabolites, extracellular vesicles, and host responses, including gene expression changes, cytokine profiles, and metabolic adaptations. Advances in multi-omics technologies, which integrate …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 29–50 Read article
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Nanoparticle-Based Early Diagnostic Tools for Tuberculosis and Malaria in Rural India
Abstract: Malaria and Tuberculosis continue to be two major public health challenges in rural India. The interplay between an inefficient health care system, late diagnosis, and under-identification of cases contributes to the high morbidity and mortality associated with TB and Malaria. Conventional methods, such as sputum microscopy for TB, microscopy and rapid diagnostic tests (RDTs) for malaria, have a higher benchmark of sensitivity that requires a certain amount of time, skilled …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 45–51 Read article
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Analysis and Application of Mathematical Modeling in Malaria Disease Control
Abstract: In this paper, we develop a mathematical model to analyze malaria transmission dynamics, as malaria is an infectious disease caused by the spread of progenitor parasites to humans through the bite of the female Anopheles mosquito. Mathematical models have long served as a framework for understanding and managing the impact of malaria, which has affected populations for over a century. Our model incorporates infected individuals who may recover and later …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 2, 2025 · pp. 19–25 Read article
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Quinine: Past, Present, and Future Perspective in Malaria and Autoimmune Disorder
Abstract: Quinine, a natural alkaloid extracted from the bark of the cinchona tree, has traditionally played a key role in treating malaria, a disease caused by parasites of the Plasmodium genus. Since its discovery in the 17th century, quinine has evolved from a rudimentary treatment to an essential component of modern antimalarial therapies. This article explores the historical use of quinine in the fight against malaria, its role in current treatment …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 24–33 Read article
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Malaria Diagnosis through Conventional Methods: A Comprehensive Review
Abstract: The incidence of drug-resistant parasite strains is rising, there is an apparent increase in the number of cases of malaria worldwide, and in a small number of cases and there has been a dramatic rise in international migration and travel. Over 1 million people die from malaria every year; 90% of these deaths are in African children, who live in tropical and subtropical regions. Although there are now efficient techniques …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 8–14 Read article
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Effect of Malaria Endemic on Socio-Economic Activities in South-East Nigeria: A Study from 2012 to 2023
Abstract: The research investigated the effects of malaria on socio-economic activities in South-East Nigeria between 2012 and 2023, emphasizing the effectiveness of different malaria management strategies. The analysis utilized both primary and secondary data, employing frequency tables and a five-point Likert scale to gauge respondents' levels of agreement. Furthermore, multiple regression models were utilized to explore the relationships among the variables.. Findings indicated that while diverse malaria interventions had a positive …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 3, 2024 Read article