macrophages
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Decoding the Mycobacterium tuberculosis–Macrophage Interplay: From Immune Defense to Pathogen Persistence
Abstract: Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (Mtb) and has been responsible for over one billion deaths worldwide over the past two centuries, remaining a major global health challenge despite advances in diagnosis and treatment. The barriers that make tuberculosis difficult to treat and eliminate are inextricably tied to its intracellular habitat. However, a research gap lies in understanding the molecular mechanisms of its survival and …
Published in International Journal of Pathogens · Vol. 3, Issue 2, 2026 Read article