Indomethacin
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Comparative Evaluation of Corneal Permeation of Indomethacin Using Different Vegetable Oil
Abstract: Topical administration of drugs is the most favoured route for management of ocular inflammation. About 90% of dose applied topically from such solutions is lost due to precorneal losses (nasolacrimal drainage) and tearing results in poor availability as contact time is less between drug and ocular tissue. An increased ocular contact time of the drug may be achieved by formulating the drug as an oil solution. In this study, invitro …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 7–12 Read article