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• Published Subscription 31 Dec 2013

  Preparation and Characterization of Microwave-assisted Candesartan Cilexetil Solid Dispersions

  By Raju Sonawane, Pravin Bonde, Vivekanand Chatap, Sanjay Bari, Laxmikant Zawar

  Abstract: The aim of the present study was to enhance the solubility & dissolution rate of a poorly soluble, BCS class II drug candesartan cilexetil (CC), using its solid dispersions (SDs) with polyethylene glycol (PEG) 6000 & hydroxypropyl methylcellulose (HPMC) E5. Solid dispersions were prepared by melting, solvent evaporation & microwave method. The dispersions were evaluated for various in vitro parameters such as solubility study, dissolution study, fourier transform infrared spectroscopy …

  Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 4, Issue 3, 2013 · pp. 9–19 Read article →