diclofenac sodium
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DESIGN AND EVALUATION OF SANDWICH TABLET FOR SUSTAINED RELEASE DRUG DELIVERY OF DICLOFENAC SODIUM.
Abstract: The objective of this experiment was to create bilayer sandwich pills using the model medication diclofenac. A lengthy duration of action is provided by the combination of an immediate and sustained release layer, which lengthens the effect in the body. Diclofenac sodium has excellent antipyretic, analgesic and anti-inflammatory effects. A super disintegrating carboxyl agent, such as methyl cellulose, is used for the quick release layer of a bilayer sandwich tablet …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 2, 2023 · pp. 1–8 Read article
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Aceclofenac and Diclofenac Sodium Conjugates with Amino Acids to Overcome Acidity
Abstract: This research work was based on a conjugate approach with some non-steroidal anti-inflammatory drugs (NSAIDs) to overcome the side effects like gastric irritation, solubility behavior, and some other effects of NSAIDs. Almost all the NSAIDs have undesirable reactions as well as they cause some types of major adverse reactions. Here the prodrugs conjugates are the approaches that increase the lipophilicity of the drug and decrease the solubility in water by …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 12, Issue 2, 2022 · pp. 19–25 Read article