Cytokine–chemokine

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• Published Subscription Review Article 31 Jan 2026

  Drug Induced Immune Mediated Nephritis: Molecular Mechanism , Pathways and Clinical Implications

  By Prahala P.R, Samina Sameer, Sandra Pillai, Kiran K J, Prasobh G R, Anusha Jasmine, Kanthlal S K

  Abstract: Drug-induced immune-mediated nephritis (DI-IMN) has become a more widely known cause of acute kidney injury (AKI), with the potential for development to chronic kidney disease if not detected and treated promptly. T-cell hypersensitivity to pharmaceuticals, such as antibiotics, proton pump inhibitors, nonsteroidal anti-inflammatory drugs, and immunological drugs, are the major causes for it. Beyond clinical burden, DI-IMN reflectsintricate molecular interactions that sustain interstitial inflammation and tubular injury. These interactions include …

  Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 13–29 Read article →