Box-Behnken design (BBD)
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Harnessing Marine Byproducts and Optimization of Biopolymer Extraction Quality Using Response Surface Methodology and Study of Its Physicochemical Properties
Abstract: Chitosan, a versatile biopolymer derived from chitin, holds immense potential across various industries owing to its antimicrobial, antioxidant, and biocompatible properties. This study aims to optimize the deacetylation process of chitin, sourced from shrimp shells, using Response Surface Methodology (RSM) to produce high-quality chitosan. The Box-Behnken Design (BBD) was employed to evaluate the effects of temperature, time, and alkali concentration on the degree of deacetylation (DD%), a key determinant of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 125–139 Read article