Antigen
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In-silico Design of Multi-epitope Vaccine for Tackling Type-1 Parainfluenza Virus
Abstract: Human parainfluenza viruses (HPIV) often cause breathing infections, particularly in kids and infants. HPIV-1 is known for causing severe croup, yet no approved vaccines exist for HPIV infections. This study employed an in-silico approach to design a potential vaccine candidate targeting the fusion glycoprotein antigen of HPIV-1. Results highlighted that B-cell and T-cell epitopes were successfully identified from the fusion glycoprotein antigen using in-silico methods. Epitopes passing antigenicity, allergenicity, and …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 10, Issue 2, 2023 · pp. 30–46 Read article