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Physicochemical Transitions and Polymerization Dynamics in Multi-Generational Dentin Adhesives: A Critical Review of the Resin-Dentin Composite Interface
Abstract: Adhesive dentistry has undergone a transformative refinement over the past three decades, transitioning from technique-sensitive, multi-step etch-and-rinse protocols to streamlined universal formulations. This narrative review critically synthesizes evidence from thirty peer-reviewed investigations to evaluate the evolution of dentin bonding agents from the fourth through the eighth generations. The analysis places particular emphasis on the physicochemical dynamics of the resin-dentin interface, including interfacial bond strength metrics, marginal integrity, and microleakage behavior. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 209–228 Read article