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Antidiabetic Activity of Triazole Derivatives: A Review
Abstract: Triazoles are the most commonly synthesized nitrogen containing hetero cyclic compounds which have a numerous biological activity viz. antifungal, antimicrobial, anthelmintic, anticancer, anti-tubercular and antiviral activities. They are 5-membered hetero ring structure containing nitrogen as heteroatom at 3 positions. Over a decade, studies are being focused on the anti-diabetic activity of 1,2,3-triazole and 1,2,4-triazole derivatives. Diabetes mellitus is a disorder in which the body doesn't produce enough insulin or does …
Published in Trends in Drug Delivery · Vol. 9, Issue 1, 2022 · pp. 1–20 Read article
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Spectral, thermal, electrochemical and biological studies of Co(II), Ni(II), Cu(II) and Zn(II) complexes derived from 4-(3-bromo-4-hydroxy-5-methoxybenzylideneamino)-3-mercapto-6-methyl-5-oxo-1,2,4-triazine.
Abstract: The Schiff base4-(3-bromo-4-hydroxy-5-methoxybenzylideneamino)-3-mercapto-6-methyl-5-oxo-1,2,4-triazine and its Co(II), Ni(II), Cu(II) and Zn(II) complexes have been synthesized and characterized by IR, NMR, electronic, ESR, fluorescence, thermal, magnetic moment and electrochemical studies. IR and thermal data support the presence of coordinated water in the metal complexes. The electronic spectral and magnetic moment measurements indicate octahedral geometry for Co(II), Ni(II) and Zn(II) complexes and square planar for Cu(II) complexes. Biological studies of the ligand and …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 5, Issue 1, 2014 · pp. 6–16 Read article
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Isolation and Characterization of 1,6-Dihydroxy-3-Methoxy-8-Methyl Xanthones from Swertia purpurascens Wall – A High Altitude Himalayan Medicinal Herb
Abstract: Normal 0 false false false EN-US X-NONE X-NONE 1, 6-dihydroxy-3-methoxy- 8- methyl xanthones from Swertia purpurascens Wall. (Gentianaceae) has been isolated along with oleanolic acid. 1,6-dihydroxy-3-methoxy- 8- methyl xanthones for the first time has been reported from this plant source and identified by means of chemical as well as spectroscopic methods.Keywords: Swertia, 1, 6-dihydroxy-3-methoxy- 8- methyl xanthones, oleanolic acid, isolation.
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 3, Issue 1, 2012 Read article