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7 articles for “thyroid hormones”
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Exploring the Thyroid Gland Physiology in Relation to Thyroid Hormones: An Overview through the Lens of 3D Computational Biology
Abstract: The endocrine system plays a pivotal role in orchestrating and sustaining diverse physiological functions by manufacturing and releasing hormones, which function as vital chemical messengers within the body. Among the prominent endocrine glands, the thyroid gland holds a central position. Situated in the lower part of the neck, this gland adopts a butterfly-shaped structure. Its significance lies in the synthesis of three key hormones: thyroxine (T4), tri-iodothyronine (T3), and calcitonin.The …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 1, 2024 · pp. 46–54 Read article
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Pharmacokinetics of Levothyroxine and Factors Influencing Its Therapeutic Efficacy in Hypothyroidism: A Comprehensive Review
Abstract: Levothyroxine (LT4) remains the standard therapy for hypothyroidism due to its effectiveness in restoring normal thyroid hormone levels and improving physiological functions. However, its pharmacokinetic profile exhibits considerable variability, which may influence therapeutic outcomes in clinical practice. This review aims to comprehensively evaluate the pharmacokinetics of levothyroxine, including its absorption, distribution, metabolism, and elimination, along with factors affecting its therapeutic efficacy. A structured literature search was conducted using electronic databases, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 Read article
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Interplay of Thyroid Dynamics in Type 2 Diabetes: A Comprehensive Analytical Study at Government Medical College, Kota, and Affiliated Hospitals
Abstract: Diabetes mellitus is a prevalent endocrine metabolic condition that causes significant morbidity and mortality globally. Innumerable metabolic processes within our bodies depend on thyroid hormones. Excess or deficiency in insulin or thyroid hormones might cause functional problems. The intricate relationship between thyroid disorders and diabetes has been recognized for a considerable period. Patients with diabetes have been known to experience thyroid malfunction, the most prevalent kind of which is hypothyroidism. …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 6–11 Read article
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Serum Magnesium, Iron, TIBC, and Hormonal Imbalances in Hypertensive Pregnant Women: A Comparative Study
Abstract: Pregnancy-induced hypertension (PIH), including gestational hypertension and preeclampsia, is a leading cause of maternal and fetal complications. The regulation of blood pressure and overall pregnancy health is influenced by micronutrients and hormones. This study aimed to evaluate serum magnesium, serum iron, total iron binding capacity (TIBC), thyroid profile, and quadruple marker levels in hypertensive pregnant women and compare them to normotensive controls. Methods: A total of 1056 hypertensive pregnant women …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 41–45 Read article
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Comprehending and Managing Restless Leg Syndrome
Abstract: An need to move that arises during rest or is made worse by rest, that happens in the evening or at night, and that goes away or gets better with movement is the hallmark of restless legs syndrome (RLS), a frequent sensorimotor disease. The degree, frequency, and age of start of symptoms vary greatly; severe types can impair mood, quality of life, and sleep. Periodic leg movements are common in …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 1, 2025 · pp. 1–6 Read article
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Assessment of Vitamin D Levels Among Hashimoto and Hypothyroidism Disease in Iraq, A Comparative Study
Abstract: The thyroid gland is a small gland that regulates the body’s metabolism. It secretes the hormones that the body needs to maintain this process. People of different ages may be afflicted with thyroid diseases, including Hashimoto disease and hypothyroidism. The current study aimed to compare the levels of vitamin D among patients with Hashimoto’s disease and hypothyroidism coming to the Diabetes and Endocrinology Center in Al-Sadr Medical City in Najaf …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 77–83 Read article
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Exploring the Role of Small Dense LDL-C and Paraoxonase-I Activity in Lipid Profile Alterations in Postmenopausal Women: Evidence from a Population-Based Study in Punjab, India
Abstract: Background: After menopause, women face a higher risk of cardiovascular disease (CVD) because hormonal changes impact how their bodies process fats. This study aimed to explore the relationship between small dense LDL cholesterol (sdLDL-C), lipid profile, PON1 levels, thyroid function, CBC parameters, and cardiovascular risk in postmenopausal women (45–60 years) in Punjab, India. sdLDL-C is more atherogenic than larger LDL particles, while PON1, linked to HDL, offers heart protection. Thyroid …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 2, 2025 · pp. 45–49 Read article