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4 articles for “thalidomide”
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A Review: Uses of Thalidomide in Cancer Treatment
Abstract: Thalidomide is an anti-angiogenetic agent, which was widely used in early 1950s and 1960s for the treatment of morning sickness in pregnant women. The drug has been banned in1960 as it caused severe birth defects in children whose mothers had used thalidomide during pregnancy. Though it caused severe adverse effects the drug has found to be effective in the treatment of leprosy and multiple myeloma. These days thalidomide has been …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 1, 2018 · pp. 1–5 Read article
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Thalidomide Reversed Chronic Anemia in Blue Rubber Bleb Nevus Syndrome: A Case Study
Abstract: Blue rubber bleb nevus syndrome is a rare disorder of cutaneous and visceral venous malformations with no standard treatment. Chronic iron deficiency anemia is common due to gastrointestinal bleeding in patients with intestinal involvement. For the first time in such a patient, we tried thalidomide that reversed her anemia.
Published in Research and Reviews: A Journal of Medicine · Vol. 2, Issue 1, 2012 · pp. 21–23 Read article
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Role of Ca125 Monitoring in Post Treatment Epithelial Ovarian Cancer Patients
Abstract: The role of routine CA125 monitoring after therapy in epithelial ovarian CA has been questioned after the results of the MRC OV-05/EORTC 55985 study have been published. However, the role of hormonal agents like Tamoxifen or Letrezole in the setting of asymptomatic rise in CA125 has not been addressed in this study, as the treatment group received second-line chemotherapy. The GOG has looked into the role of Tamoxifen and also …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 4, Issue 2, 2015 · pp. 17–20 Read article
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Pharmacovigilance: The Silent Guardian of Patient Safety
Abstract: Pharmacovigilance is critical in protecting the populace health by monitoring, detecting and preventing adverse drug reaction (ADR) post drug approval. Although there is technological advancement and national initiatives such as the Pharmacovigilance Programme of India (PvPI), there is still a great problem of underreporting. Many benefits of effective pharmacovigilance include identification of risks early, better prescriptions and patient confidence. There are historical examples of drugs being withdrawn due to thalidomide, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 01–05 Read article