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2 articles for “succinylcholine”
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Comparative Study of Rocuronium Bromide and Succinylcholine Regarding Ease of Intubating Conditions and Hemodynamic Parameters for Rapid Sequence Intubation in Adults
Abstract: Background: Rapid Sequence Intubation (RSI) is an airway management procedure designed to quickly secure the airway while reducing the likelihood of gastric aspiration during anesthesia induction. For many years, Succinylcholine has been regarded as the preferred neuromuscular blocking agent for RSI because it produces muscle relaxation rapidly and has a relatively brief duration of action. However, its adverse effect profile – including hyperkalemia, bradyarrhythmias, malignant hyperthermia, and increased intracranial and …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 2, 2026 · pp. 33–39 Read article
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Pharmacogenomics in Anesthesia: Case Studies and Clinical Applications for Personalized Care
Abstract: Pharmacogenomics, the study of how genetic variability influences individual responses to medications, is transforming anesthetic practice by enabling personalized care. This case study collection explores the integration of pharmacogenomic insights into anesthesia management, highlighting its impact on safety, efficacy, and patient outcomes. Adverse reactions to anesthetics often arise from genetic polymorphisms that alter drug metabolism or sensitivity. For instance, patients with RYR1 mutations are susceptible to malignant hyperthermia (MH) when …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 85–91 Read article