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3 articles for “rituximab”
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Thrombotic thrombocytopenic purpura: A Narrative Review of Diagnosis and Treatment by drugs and novel agents.
Abstract: Thrombotic thrombocytopenic purpura (TTP) is an infrequent but fatal disease, is primarily caused by autoantibodies against the von Willebrand factor (VWF) cleaving metalloprotease ADAMTS13. Overall, severe deficiency of plasma ADAMTS13 action (< 10 IU dL-1) with or without noticeable inhibitory autoantibodies counter to ADAMTS13 supports the diagnosis of TTP. The International Working Group for TTP released a consensus statement on the standardization of terminology in these disorders which we use …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 10, Issue 1, 2021 · pp. 40–55 Read article
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Monoclonal Antibody (mAb) Drugs in Cancer Therapy
Abstract: Monoclonal antibodies (mAb) are widely used in the diagnosis of diseases, detection of marker molecules and in therapy. The mAb drugs are increasingly used to treat hypersensitivity, autoimmune diseases, transplantation rejection and more importantly in cancer therapy. Although the application of mAbs in the treatment of infectious diseases is limited, the wide acceptance of these drugs in cancer therapy is remarkable. As of 2011, at least 11 FAB approved mAb …
Published in Research and Reviews : A Journal of Immunology · Vol. 2, Issue 2, 2012 · pp. 6–10 Read article
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An Emerging Cause of Treatable Encephalitis: A Case of Anti-NMDA receptor (NMDAR) Encephalitis
Abstract: Anti-NMDA Receptor encephalitis is the most common type of autoimmune limbic encephalitis known. It is characterised by sub-acute onset of psychiatric symptoms along with refractory epilepsy, orofacial and limb dyskinesia and dysautonomia. High clinical suspicion and appropriate antibody testing in cerebrospinal fluid (CSF) and serum is required for early diagnosis and initiation of immunotherapy. Delay in treatment may lead to significant permanent neuro-deficits as well as mortality. Here, we present …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 7, Issue 3, 2017 · pp. 8–11 Read article