Search
14 articles for “renal cancer”
-
Therapeutic Effects of Metformin on Cancer: A Possible Option in Cancer Chemotherapy
Abstract: Metformin is being used for an elongated period of an antidiabetic medicine for type 2 diabetes. It is used moreover as a monotherapy or in mixture with additional antidiabetic medications. The drug derived into importance in diabetes and other circumstances with cardiovascular risk after the landmark study of 1995 by the United Kingdom Prospective Diabetes Study which highlighted its reputation. The usage of metformin, the usually given drug for type …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 8, Issue 1, 2023 · pp. 46–68 Read article
-
Progress in Renal Tumor Surgery: The Role of 3D Surgical Planning in Partial Nephrectomy
Abstract: Renal cell carcinoma is the most common form of kidney cancer, representing 2–3% of global cases, with the highest incidence in Western Europe. For small renal tumors, partial nephrectomy is the preferred treatment, where the tumor is surgically removed. This procedure does not affect oncological outcomes, allowing part of the kidney to remain functional. During tumor removal, the surgeon minimizes excessive bleeding and improves visibility by cutting off the arterial …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 3, 2025 · pp. 35–40 Read article
-
Review on Histological Effect of Lead on Liver and Kidney
Abstract: Our environment can be polluted by environmental toxins which are chemicals and other materials produced largely from industry and its products. There are large numbers of environmental toxicants which are potentially harmful to health. These large numbers of environmental toxicants can be divided into three major categories (heavy metals, air pollutants, and pesticides) and they are commonly studied environmental toxicants. Environmental toxins can be entered into the body by various …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 1, 2020 · pp. 8–29 Read article
-
Gene Annotation of Cancer Vaccine for Homo sapiens
Abstract: Objectives: Gene annotation helps us to deduce the structural and functional aspects of a gene that encodes for a functional protein in our body. Thus, by determining the coding sequence and gene location we can derive meaningful insights as to what these genes do in our body. In this study, an unknown gene, cancer vaccine for Homo sapiens has been studied and annotated. Methods: This study was based on a …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 1–14 Read article
-
Protective Role of Sulforaphane against Multiorgan Toxicity in Rats: An In-vivo and In-vitro Review Study
Abstract: Sulforaphane [1-isothiocyanate-(4R) -(methylsulfinyl) butane] is a natural dietary isothiocyanate produced by the enzymatic accomplishment of the myrosinase on glucopharanin, a 4-methylsulfinylbutyl glucosinolate contained in cruciferous vegetables such as broccoli, brussel sprouts, and cabbage. Exploring of this compound against various oxidative degenerative diseases such as hepatic, nephro and cardiac diseases is growing because of its anticarcinogenic and cytoprotective properties. In several invivo and invitro experimental paradigms proved SFN and its compounds …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 1, 2018 · pp. 1–8 Read article
-
Dieto-Therapy (Ilaj-bil-ghiza) in Unani System of Medicine: From Concept to Practice in the Management of Non-communicable Diseases
Abstract: Unani physicians paid a great attention towards ilaj-bil-ghiza (dieto-therapy). They used to treat a number of ailments by alteration in quantity and/or quality of Ghiza. Their knowledge about its nutritive as well as its pharmacological activity was vast as evident from the Unani classical literature. The classification of Unani drugs is based on medicinal and nutritive values. The former is known as dawa and later is ghiza. Further, a combination …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 4, Issue 2, 2015 · pp. 54–59 Read article
-
Nephrotoxic Effect of Herbal Medicine and Supplements: A Review
Abstract: Nowadays, alternative medicines have become a multibillion-dollar industry and continue growing. Herbal medicine is one of the primeval forms of medicine which is prepared exclusively from herbal plants. The Ayurvedic medicinal cure method is also been used as a prescription for chronic diseases such as cancer, asthma, diabetes, and end-stage renal diseases and increasing interest in European countries respectively. According to the report of world health organization (WHO), 4 billion …
Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 2, 2019 · pp. 28–35 Read article
-
A Review on Comprehensive Therapy of Ascites Cancer
Abstract: Ascites cancer is a condition in which there is a fluid accumulation in the peritoneal cavity due to diseases like liver disease, heart failure, renal disease and malignancy. Approximately 50% of all cirrhotic patients develop ascites cancer every year. The average survival after development of malignant ascites is only about 5 months. The most common symptoms of Ascites are recent weight gain, increased abdominal girth and dyspnoea. The development of …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 1, 2018 · pp. 1–6 Read article
-
Sources and Health Effects of Arsenic, Fluoride, and Nitrate in Water
Abstract: Arsenic, fluoride, and nitrate are major inorganic contaminants in water that pose significant risks to human health. These contaminants are introduced into water sources through both natural geological processes and human activities. Arsenic is primarily released from arsenic-bearing minerals through weathering, dissolution, and erosion, while human activities such as agriculture, mining, and fossil fuel combustion further enhance its presence in water. Fluoride contamination mainly results from the dissolution of fluoride-bearing …
Published in Journal of Water Resource Engineering and Management · Vol. 13, Issue 2, 2026 · pp. 19–25 Read article
-
Arsenic Induced Oxidative Stress and Its Possible Reversal by Chelation Therapy
Abstract: Arsenic (As) is a metalloid listed in group Va of the periodic chart. It exists in nature in the oxidation states +V (arsenate), +III (arsenite), 0 (arsenic) and −III (arsine). In the aqueous environment inorganic arsenic appears commonly in the oxidation states +V and +III as arsenous acid (As (III)), arsenic acid (As (V)), and their salts. Chronic and acute exposures of arsenic leads to cancer, cardiovascular disease (hypertension and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 2, 2012 · pp. 16–37 Read article
-
Morphine: A Pharmacological Perspective on Its Cancer Pain Management
Abstract: Morphine continues to be a key treatment in managing cancer pain because of its strong pain-relieving effects and established clinical history. Despite the emergence of alternative opioids and pain management therapies, morphine continues to be widely prescribed, particularly in palliative care settings. However, its use has been accompanied by concerns regarding tolerance, dependence, and adverse effects, which complicate long-term administration. This review explores the pharmacological aspects of morphine in cancer …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 1–8 Read article
-
A REVIEW: P-GLYCOPROTEIN AND ITS ROLE IN CANCER
Abstract: Abstract The review is done on how P-glycoprotein recognizes various substrates and plays a key role in cancer. Chemotherapy is used for cancer treatment but multidrug resistance of cancerous cell is the major obstacle in therapy and also an important aspect which causes failure in the treatment by effluxion of a xenobiotic on the plasma membrane. In humans, P-glycoprotein is important transmembrane transporter. It is located on the apical surface …
Published in Trends in Drug Delivery · Vol. 7, Issue 2, 2020 · pp. 26–34 Read article
-
Treatment of Korean Panax Ginseng against Cisplatin-Induced Toxicity in Rats Haematological and Histological Examination of Liver, Spleen and Kidney
Abstract: Vital goal of all anti-cancer therapies are to prevent the incidence of side effects either through more selective therapeutic methodology that target only neoplastic cells or through the use of complementary or alternative medicine. Present study investigated the effects of Panax ginseng (PG) on cisplatin-induced haematological and histopathological (liver, kidney and spleen) changes in rats. Rats were administered with PG (25, 50, 100 mg/kg) before or after an intraperitoneal injection …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 2, 2013 · pp. 35–39 Read article
-
A Study and Report on Impact of Clinical Pharmacy Services Over Indian Health Care System in the Management of Chronic Disorders/Diseases in Hospital
Abstract: The study aims to ensure safe, effective, economic, and patient friendly with the knowledge inputs of each professional practice. With the primary and secondary objectives being: to study the role of the clinical pharmacist/doctor of pharmacy professional in the management of chronic diseases/illness, minimise medication/prescription errors, minimise/prevent adverse drug reactions, all types of drug interactions, and unnecessary healthcare costs, reducing drug-related problems and to monitor drug therapy efficiently, attain desired …
Published in Research and Reviews: A Journal of Health Professions · Vol. 11, Issue 2, 2021 · pp. 46–82 Read article