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5 articles for “redox signaling”
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The Redox Rheostat: A Review on Targeting the Oxidative Stress-to- Cell Death Continuum for Therapeutic Gain
Abstract: For a long time, oxidative stress was cast as a plain villain, something to be pushed down with antioxidants wherever it appeared. That view has changed. Reactive oxygen species (ROS) do real work in the cell. At low concentrations, molecules such as hydrogen peroxide act as signals. As stress increases, cells activate protective mechanisms to keep themselves safe. However, if the stress becomes too strong or lasts too long, these …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 2, 2026 Read article
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Development of Polymersomes as Macromolecular Platforms for Nanomedicine
Abstract: The conventional method of drug delivery is plagued with instability, low targeting and low bioavailability. A solution to these shortcomings is the use of polymersomes, artificial vesicles that are produced through self-assembly of amphiphilic block copolymer, and they are suggested as universal nanoscale carriers. They have stiff, tunable membranes (thickness = 2–50 nm) due to accurate control of polymer chemistry, chain length, and hydrophilic mass fraction (f), which allows predictability …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 · pp. 71–89 Read article
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Biopolymer-Based 3D Composite Scaffolds for Bone Tissue Engineering: Photothermal-Responsive Systems with Controlled Pt (IV) Prodrug Release
Abstract: Biopolymer-based composite scaffolds have attracted significant attention as multifunctional platforms at the intersection of polymer science, regenerative medicine, and cancer nanotherapy. In this study, a dual-functional scaffold was developed for simultaneous osteosarcoma treatment and bone regeneration using poly (L-lactic acid) (PLLA) reinforced with bioactive glass (BG) and integrated with a glutathione-responsive platinum (IV) prodrug system (PDA@Pt). To improve interfacial adhesion, photothermal conversion efficiency, and tumor-specific activation, the Pt (IV) prodrug …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 351–361 Read article
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Nutrient-Mediated Activation of Cellular Signaling Pathways: Mechanistic Insights into Attenuation of Toxin Induced Inflammation in Food Animals
Abstract: Dietary and environmental toxins remain a persistent challenge in food animal production, where subclinical and clinical inflammation compromises health, productivity, and food safety. Toxin induced inflammation is driven by oxidative stress, mitochondrial dysfunction, and dysregulated immune signaling, resulting in impaired metabolic efficiency and increased disease susceptibility. Recent advances in nutritional science have revealed that nutrients act not only as substrates for growth but also as signaling molecules capable of modulating …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 1–12 Read article
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Altitude Related Variation of Antioxidant Properties of Tea Leaf (Camellia sinensis)
Abstract: Places, in the high altitude are subject to higher UV radiation as compared to places of low altitude, provided they bear the same latitudinal location. Here, in this investigation, the oxidative stress and associated cell protection in tea plants growing in Mysore (12°30′ N 76°65′ E, 770 m) and Ooty (Dodabeta – 11°4090′ N, 76°6966′ E, 2623 m) has been studied. The UV radiation varies in these two places – …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 4, Issue 2, 2014 · pp. 1–6 Read article