Search
6 articles for “red blood cells (RBCs)”
-
Estimation of Effective Storage Time in Post-thawing and Washing Cryopreserved Red Blood Cells using Mechanical Properties of Membrane by Dielectrophoresis
Abstract: Aim: The aim of the study is to estimate most effective storage time after thawing and washing in cryopreserved red blood cells(RBCs), using the mechanical properties of red blood cells(RBCs) membrane by dielectrophoresis. Materials and Methods: The mechanical properties of the RBCs membrane(elasticity, electric capacity and interactive energy) were calculated by mathematical model made from dielectrophoresis on RBCs. In addition, estimating the most effective storage time after thawing and washing …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 10, Issue 1, 2021 · pp. 31–39 Read article
-
A Review on RBC-Hitchhiking as a Novel Drug Delivery System
Abstract: Red Blood Cells (RBCs) are the human body's most abundant cells. Transferring oxygen to cells and body tissues is their main function. Owing to their unique biological properties, they are very useful for drug delivery. Due to their biocompatibility and known protection in transfusions, RBCs are especially attractive carriers. RBCs are biodegradable, possess very long circulation half-lives. The vast majority of drugs fail because they disperse across the body, landing …
Published in Trends in Drug Delivery · Vol. 8, Issue 1, 2023 · pp. 1–4 Read article
-
Advanced Deep Learning Techniques for Sickle Cell Anaemia Detection
Abstract: Sickle Cell Anemia (SCA) is a prevalent genetic blood disorder characterized by the presence of abnormal hemoglobin, resulting in the distinctive sickle shape of red blood cells. Timely and accurate identification of Sickle Cell Anemia (SCA) is essential for effective management and treatment. This study presents a new method that utilizes Convolutional Neural Networks (CNNs), a deep learning model particularly effective for image analysis. The process involves using microscopic images …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 3, 2024 · pp. 9–15 Read article
-
The Curious Case of the Sphered Blood Cells: Unveiling Hereditary Spherocytosis
Abstract: Hereditary spherocytosis (HS) is an inherited blood disorder that disrupts the shape and flexibility of red blood cells (RBCs) due to genetic mutations. These abnormal, sphere-shaped RBCs, called spherocytes, are prematurely destroyed in the spleen, leading to hemolytic anemia. Symptoms range from mild fatigue to chronic weakness and shortness of breath. While incurable, Hereditary spherocytosis can be effectively managed. Regular monitoring, folic acid supplementation, and in severe cases, splenectomy (surgical …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 49–57 Read article
-
Blood Cell Saver Machine
Abstract: Intraoperative Cell Salvage (ICS) is a crucial technique in modern surgical practice aimed at minimizing the need for allogeneic blood transfusions. By collecting, filtering, washing, and re-infusing a patient’s own blood lost during surgery, ICS provides a safer and cost-effective alternative to donor transfusion, reducing the risk of transfusion-related infections and immunologic reactions. Initially conceptualized in the early 19th century, ICS technology evolved significantly with the introduction of the Cell …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 2, 2025 · pp. 51–59 Read article
-
Iron Deficiency Anemia: From Historical Background to Management—A Review
Abstract: The word anemia comes from the ancient Greek word άναιμία, anaimia, meaning ‘lack of blood’. Simply, anemia means a decrease in the total amount of hemoglobin (Hb) or the number of red blood cells (RBCs). Anemia remains a widespread public health problem with major consequences on human health as well as social and economic development. Globally, the most significant contributor to the onset of anemia is iron deficiency (ID) so …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 1, 2020 · pp. 29–40 Read article