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80 articles for “pharmaceutical standardization”
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Pharmaceutical Standardization of Rakta Akika Bhasma and Pishti
Abstract: Background: Akika Pishti is widely used in therapeutics to treat various disease conditions like Hridaroga (Cardiac disease) Manoroga (psychic disorders) and Raktaja Vikara (bleeding disorders). Some references found in classics also emphasized the use of Akika Bhasma. However, no work has been done to date to standardise Rakta Akika Bhasma and Pishti's pharmaceuticals. Aim: The present research work is aimed to establish the pharmaceutical standardization of Rakta Akika Bhasma and …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 9, Issue 2, 2022 · pp. 20–29 Read article
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Pharmaceutical Standardization and Preliminary assay of Kokilaksha (Asteracantha longifolia nees.) Ghana
Abstract: Introduction: Kokilaksha (Asteracantha longifolia Nees.) is an annual herb belonging to the acanthaceae family. In classics, Kokilaksha Kwatha (Decoction) is stated in the treatment of Nidranasha (Insomnia), Vatarakta (Gout), Shoola (Pain) and many more. Panchavidha Kashaya Kalpana (five basic preparation) are primary potent preparations of Ayurved pharmaceutics from which several additional preparations are developed as per need of time like Vati (Pills), Avaleha (Lincus), Ghana (Solidified aqueous extract), Kshara (Alkali) …
Published in Research & Reviews : Journal of Herbal Science · Vol. 12, Issue 3, 2023 · pp. 21–29 Read article
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Analytical Technique Optimization and ICH-Directed Verification of a Reverse Phase HPLC Approach for Quantification of Bupropion Hydrochloride
Abstract: This method was developed for retention time, peak resolution and baseline response using Bupropion Hydrochloride under optimized conditions as validation. The method resulted in two well separated, well defined peaks, a minor peak at 7.5 minutes 12 mV and a main peak at 11.52 minutes 150 mV. At the same time, the baseline has remained stable during the chromatographic run and the fluctuations of noise are very small (0.5 ± …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 47–54 Read article
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Standard Manufacturing Procedure (SMP) of Jaharamohara Bhasma Prepared by two Methods
Abstract: Introduction: Jaharamohara (Serpentine) is an important drug of Ayurveda and Unani medicine. In the literature of Rasashastra it is classified under Sikta Varga (group of silica containing drugs). In classical texts, different Bhavana Dravya (levigating material) are advised for the preparation of Jaharamohara Bhasma which enhances its potency. However, no work has been done till date to standardize Jaharamohara Bhasma by two different methods. Aim: An attempt has been made …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 1, 2024 · pp. 1–13 Read article
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A Review on Transforming Patient Pathways: The Impact of Pharmaceutical Software on Drug Manufacturing and Safety Monitoring
Abstract: The development, production, and safety monitoring of pharmaceuticals are being revolutionized by incorporating digital technologies. Throughout drug lifecycles, pharmaceutical software which includes cloud-based systems, automation, data analytics, and artificial intelligence (AI) has emerged behind efficiency and innovation. Real-time monitoring, predictive maintenance, and process optimization are made possible in manufacturing by software tools like Digital Twins, Manufacturing Execution Systems (MES), and Quality Management Systems (QMS). These technologies improve batch consistency, lower …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 40–46 Read article
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Pharmacognostical and Pharmaceutical Analysis of “Ashtanga Ghrita - A Poly Herbal Ayurvedic Formulation”
Abstract: AbstractAyurveda is having ample of collection of formulations for effective management of diseases. In the era of geometrical rise of demand for indigenous medicines, maintaining quality standards is the need of hour. Absence of reference standards for compound formulations is a hindrance on the way towards standardization. The present study was aimed at setting a standard pharmacognostical and pharmaceutical profile of Ashtanga Ghrita. The study included preparation of Ashtanga Ghrita …
Published in Research & Reviews : Journal of Herbal Science · Vol. 2, Issue 3, 2013 · pp. 24–28 Read article
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Implementing Quality by Design (QbD): Strategies, Challenges, and Best Practices across Industries
Abstract: The present comprehensive review investigated the dynamic landscape of quality standards within the pharmaceutical sector, with a primary focus on the implementation and impact of Quality by Design principles. It illuminated the multifaceted challenges encountered by pharmaceutical companies in upholding stringent quality standards amidst evolving regulatory requirements and complex manufacturing processes. By embracing Quality by Design principles, the industry aims to foster a proactive and systematic approach to product development …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 28–36 Read article
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Recent Advances in Quality Control and Quality Assurance: Enhancing Pharmaceutical Product Integrity and Compliance
Abstract: The pharmaceutical industry is undergoing a paradigm shift driven by stringent regulatory expectations and the demand for high-quality, safe, and efficacious drug products. Quality Control (QC) and Quality Assurance (QA) serve as the two foundational pillars that ensure pharmaceutical integrity from raw material acquisition through to product release. Traditional QC and QA practices, while effective, have been challenged by complex formulations, biologics, and personalized medicine, requiring innovative methodologies and technologies. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 54–62 Read article
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Importance of Rasaushadhis in Ayurvedic Therapy and Recent Advances in the Field of Bhasma and Kupipakwa Rasayana
Abstract: Ayurveda is a science of life and deals with the one medicine known as Dravyaaushadhis or Rasaushadhis. The final aim of this is to achieve Bhukti and Mukti that prolongs life span and manufactures positive health. Ayurveda is based on tridosha and four folds of treatment.In Ayurveda, many types of medicines are used for the treatment of diseases such as herbal, modern, herbal medicines, herbomineral medicines, and minerals/metals called as …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 5, Issue 2, 2016 · pp. 24–27 Read article
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Sophisticated instrumental analysis of Trinakantamani Pishti by various methods.
Abstract: Trinakantamani Pishti was prepared by reference of Bheshaja Samhita, Bhasma-Pishti Prakarana 1 , which is indicated for Vataja, Pittaja and Kaphaja Galagraha, Gala Granthi, Gandamala. Aim- to standardize Trinakantamani Pishti pharmaceutically. Methods- Trinakantamani Pishti was prepared as per reference of Bheshaja Samhita, Bhasma-Pishti Prakarana and it was analysed by various sophisticated instrumental analysis method like SEM (Scanning Electron Microscopy) and EDX (Energy Dispersive Spectroscopy), X-ray Diffraction (XRD), Particle size analysis …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 1, 2023 · pp. 7–13 Read article
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Rapid Determination of Content of Etoricoxib in Pharmaceutical Formulations by Mid-Infrared Spectroscopy
Abstract: The present paper is an attempt to highlight a new technique FTIR-ATR along with its referenced validated method, UV spectrophotometric analysis. Different concentrations of etoricoxib were used as samples to draw standard plot. From different samples, a transmission spectrum was recorded according to the prominence of peaks. The present study has chosen the three most prominent peaks for analytical purpose in case of samples of etoricoxib and marketed formulations. All …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 4, Issue 3, 2013 · pp. 20–32 Read article
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Development and Validation of a Gradient RP-HPLC Method for Quantitative Determination of Potential Manufacturing Impurities in New Drug Apronalide and Pharmaceutical Formulations
Abstract: Three impurities in apronalide drug substance were detected and quantified using a simple isocratic reverse phase HPLC method. The chromatographic separation was achieved on a Thermo Hypersil gold-CN, 100 A0 5 µm, and 250X4.6 mm using a mobile phase consisting of phosphate buffer (pH-4.6) - Methanol with UV detection at 210 nm and flow rate of 0.8 ml/min. The column temperature was maintained at 250C throughout the analysis. This method …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 1, Issue 1, 2014 · pp. 1–10 Read article
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Agricultural Residues as Pharmaceutical Excipient
Abstract: Excipients development has become a core area of research in pharmaceutical drug delivery. Agricultural residues and natural sources represent a potential source of inexpensive pharmaceutical excipients. Pharmaceutical excipients have vital roles in drug formulations and dosage forms and are used as thickeners, gelling, bulking and water retention agents, fillers, binders, disintegrants, lubricant and/or glidant, flavours and sweeteners. Microcrystalline cellulose (MCC), a very important directly compressible excipient widely used in pharmaceutical …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 3, 2014 · pp. 1–7 Read article
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Identification and Standardization of Crude Drugs according to Ayurvedic and Modern Parameters
Abstract: Medicinal plants constitute a source of raw material for both traditional system of medicine and modern medicine. Now plant materials are employed throughout the pharmaceuticals industries, developing world as home remedies and ingredients for the industry. Standardization of herbal drugs in this globalization phase of Ayurveda bears utmost significance because this can sustain the tremendous interest that Ayurveda is witnessing across the globe. The increased use of herbal drugs and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 4, Issue 1, 2017 · pp. 11–16 Read article
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Development and Validation of a High Performance Liquid Chromatographic Method for Related Substances of Raloxifene Hydrochloride in Bulk and Pharmaceutical Formulations
Abstract: The development and validation of reversed phase liquid chromatographic method for the determination of the related substances of Raloxifene Hydrochloride (RLH) in bulk and pharmaceutical formulation is describe. This method is simple isocratic for separation of Raloxifene Hydrochloride and related substances from each other in a thirty minutes run time. To the best of our knowledge, no method described previously in the literature has demonstrated resolution of RLH from this …
Published in Trends in Drug Delivery · Vol. 1, Issue 1, 2014 · pp. 16–23 Read article
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Titrimetric and Spectrophotometric Assay of Diethylcarbamazine Citrate in Pharmaceuticals using Permanganate as Oxidant
Abstract: Two titrimetric and one spectrophotometric methods are described for the determination of diethylcarbamazine citrate in bulk drug and dosage forms using permanganate as an oxidimetric agent. In method A, the drug solution in H2SO4 is titrated directly at 800C to a pink end point. DEC was treated with a measured excess of standard permanganate in H2SO4 medium, and after a contact time of 5 min, the residual oxidant back titrated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 7, Issue 3, 2016 · pp. 1–11 Read article
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Regulatory Requirements for Pharmaceutical Product Registration in Zambia
Abstract: There is a significant burden of diseases in Zambia and its neighboring countries, such as malaria, HIV/AIDS, and other ailments. These health challenges necessitate a high consumption of pharmaceutical products. Currently, the majority of essential health drugs in Zambia are imported from outside of Africa. This reliance on external sources presents an opportunity for new investments in the local manufacturing of pharmaceutical products. Although Zambia may not be the largest …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 33–41 Read article
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Assets and Liabilities of Commodification of Herbal (Ayurvedic) Medicine
Abstract: Herbs have been used since many decades as medicines for the treatment of various ailments. Indian system of medicine recommends different Ayurvedic formulations and multi-compound extracts. This ancient pharmacological techinque is beneficial in many diseases related to multiple causes such as chronic illness. In Classics various methods of preparation of Ayurvedic formulation have been described and these formulations are given to patients according to disease (vyaadhi), their constitution (Prakiti), pathology …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 9, Issue 2, 2022 · pp. 33–38 Read article
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Nanotechnology’s Emerging Frontiers
Abstract: Nanotechnology holds significant promise across diverse sectors, including agriculture, food processing, energy, transportation, and communication systems. This swiftly evolving domain revolves around the development of groundbreaking materials and devices that tackle intricate engineering and scientific hurdles across various sectors. In agriculture and food processing, nanotechnology unfolds a myriad of potentialities. Its potential extends to the development of various products such as nano-fertilizers, nano-herbicides, nano-pesticides, and nano-scale carriers. Additionally, it plays …
Published in Journal of Petroleum Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 14–23 Read article
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A Comparative Pharmacognostical and Pharmaceutical Study of Haritaki (Treesa) and Gomutra Haritaki w.s.r to Pancha Mahabhuta Composition
Abstract: Haritaki is considered as king of the medicine. It is described as prime ingredient in many formulations with different indications. Among them, Gomutra Haritaki is processed form of Haritaki which has additional qualities over Haritaki. Maintaining quality standard is must in the era of increasing demand for traditional medicines. The present study was aimed to compare pharmacognostical and pharmaceutical profile of Gomutra Haritaki with Haritaki (Treesa) alone. Haritaki (Treesa) and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 2, Issue 3, 2015 · pp. 1–10 Read article