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4 articles for “paratuberculosis”
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Potential Etiologic Link and Association between Mycobacterium avium subspecies paratuberculosis and Crohn’s Disease in Humans
Abstract: Mycobacterium avium subspecies paratuberculosis, the cause of incurable, chronic enteritis called as Johne’s disease or paratuberculosis in animals, has also been associated with Crohn’s disease in human beings. Scientific opinion is divided on the possible role of Mycobacterium avium subspecies paratuberculosis in the etiopathogenesis of Crohn’s disease. Though etiology of Crohn’s disease is still unclear, however, in addition to genetic and environmental factors, microorganisms have been considered as potential agents. …
Published in Research and Reviews : A Journal of Immunology · Vol. 2, Issue 1, 2012 · pp. 13–26 Read article
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Comparative evaluation of improved ‘Modified Microscopic Test’ with traditional microscopy, indigenous ELISA kit, fecal and blood PCR for the diagnosis of Mycobacterium avium subs paratuberculosis in goat herd endemic for Johne’s disease
Abstract: Presently available tests for the diagnosis of Mycobacterium avium subspecies paratuberculosis (MAP) infection were frequently used by several laboratories in developed countries, however, low income countries further required a test of affordable price or cost for small ruminants. Therefore, in present study five test, ‘Hexadecyl Pyridinium Chloride (HPC) processed fecal microscopic’ test (test 2), traditional microscopy (test 1), ‘indigenous ELISA kit’ (test 5) and ‘fecal IS900 PCR (test 3) and …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 1, Issue 1, 2011 · pp. 10–18 Read article
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Interspecies Sharing of “Indian Bison Type,†A Novel Predominant Genotype of Mycobacterium Avium Subspecies Paratuberculosis between Naturally Infected and Endemic Flocks of Bharat Merino Sheep and a Colony of Rabbits (Oryctolagus Cuniculus) Raised on the
Abstract: Mycobacterium avium subspecies paratuberculosis (MAP) is endemic in domestic and wild ruminants and non-ruminant animal population of India. Native “Indian Bison type” genotype of MAP has emerged as the predominant genotype with an impressive list of hosts cutting across species and has emerged as a major animal pathogen with significant zoonotic concerns. The present study has for the first time investigated the status of MAP infection in a colony of …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 2, Issue 3, 2012 · pp. 1–8 Read article
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Molecular Diagnosis of Rifampicin Antibiotic Resistance in Mycobacterium Avium Subspecies Paratuberculosis Isolated from Sheep Clinical Samples
Abstract: The present study was conducted to identify parts of the rpoB gene in MAP of Indian sheep isolates. The rpoB gene (Beta sub unit of RNA polymerase) is involved in conferring the rifampicin antibiotic resistance in MAP bacteria. The resistance is due to the presence of mutations in the 81 bp variable region of the rpoB gene including C1367T and T1442C mutations identified by several workers. The study was further …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 12, Issue 3, 2022 · pp. 35–56 Read article