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5 articles for “microcrystalline cellulose”
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Fabrication and Analysis of PBAT/Cyperus Rotundus Micro Crystalline Cellulose Biofilms for Food Packaging Applications
Abstract: Global plastic waste crisis has gained an increasing attention and many efforts have been made recently to develop biodegradable polymers as food packaging alternatives. Solution casting is used for fabrication and characterization of reinforced polybutylene adipate-co-terephthalate (PBAT) biofilm with Cyperus rotundus microcrystalline cellulose (CRC). PBAT-CRC biofilms with different CRC loadings (1%, and 2%) had been prepared and their structural, mechanical, thermal and morphological properties of fabricated biofilms were analyzed to …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 591–599 Read article
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Comparative Study on Oro Dispersible Tablets of Candesartan Cilexetil Formulated with Natural and Synthetic Disintegrants
Abstract: Candesartan cilexetil, a BCS class II drug with low aqueous solubility and poor bioavailability (15%), poses challenges for oral delivery. To address this limitation, the present study focuses on polymer-based inclusion complexation and composite formulation strategies to enhance solubility and dissolution behavior. The drug was incorporated into β-cyclodextrin (β-CD), a cyclic oligosaccharide polymer, by the kneading method in different drug-to-carrier ratios. Among these, the 1:1 molar ratio complex exhibited the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 687–695 Read article
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Innovative Approaches in Excipient Co-Processing: A Comprehensive Review
Abstract: Co-processing of existing excipients is an innovative strategy in pharmaceutical formulation that offers a cost-effective, efficient alternative to the development of entirely new excipients. This process involves combining two or more well-established excipients to create new material with enhanced properties, thereby improving the functionality, performance, and manufacturability of pharmaceutical products. By leveraging the unique characteristics of each excipient, co-processing can significantly enhance attributes, such as flowability, compressibility, solubility, stability, and …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 34–51 Read article
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Sustainable Epoxy Composites Enhanced by Cellulose Nanocrystals for Structural and Thermal Applications
Abstract: This study presents the advancement and behaviour analysis of sustainable nanocomposites reinforced with cellulose nanocrystals (CNCs), a biodegradable and high-aspect-ratio nanofiller derived from microcrystalline cellulose. CNCs were incorporated into a bisphenol-A-based epoxy matrix at varying concentrations (0, 1, 3, 5, and 7 wt%) to assess their influence on mechanical, thermal, and viscoelastic properties. The tensile strength of the composites increased significantly, from 45 MPa for neat epoxy to 65 MPa …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 126–134 Read article
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Design and Assessment of Fixed Dose Combination Containing Fenofibrate and Pravastatin Sodium in Tablet Formulation: A Bioinformatics Approach
Abstract: The aim of this is study is to formulate and evaluate fixed dose combination of Fenofibrate and Pravastatin sodium in tablet dosage for the treatment of Dyslipidemia. For the formulation and optimization of fenofibrate layer, two factor three level factorial design was used as experimental design for optimization with a minimum of nine run. All the nine trial (F1–F9) has been formulated according to the experimental design by wet granulation …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 1, 2024 · pp. 1–20 Read article