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2 articles for “indomethacin gastric model”
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Anti-ulcer Properties of Methanol Extract and its Solvent Fractions of Stem Bark of Lannea acida on Indomethacin Induced Gastric Ulcer in Albino Rats
Abstract: Lannea acida is use in Nigeria for the treatment of Peptic ulcers. The methanol and its solvent fractions (hexane, ethylacetate and butanol) of the stem bark of Lannea acida were evaluated for antiulcerogenic activity using indomethacin model. The anti-ulcerogenic mechanisms of the plant using the model employed in this study were done by estimation of Superoxide dismutase (SOD), Glutathione (GSH), Catalase (CAT), Vitamins A, C and E, and Malondialdehyde (MDA). …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 11, Issue 3, 2023 · pp. 20–35 Read article
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Anti-Ulcer Activity of Ethanolic Extract of Sesamum indicum Seed on Indomethacin-Induced Ulcer Model and Its Antioxidant Property in Gastro-Protection
Abstract: The present study was intended to investigate and evaluate the antiulcer activity of the ethanol seed extract of Sesamum indicum Linn. using Indomethacin Induced Ulcer in Albino rats and to determine its link between oxidant or antioxidant parameter. The extract of Seamum indicum Linn. was tested on indomethacin induced gastric ulcer in Albino rats. The antiulcer activity of high dose (400 mg/kg) and low dose (200 mg/kg) of ethanolic extract …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 2, 2015 · pp. 18–25 Read article