Search
2 articles for “hyperpolarization”
-
Role of ion Regulation in Heartbeat Initiation
Abstract: The heart can beat quite 2 billion times in normal life, but the mechanism by which the guts beats is that the subject of intense research. Since the invention of pacemaker currents in 1978, several studies have shown that rhythmic changes in membrane tension (the "membrane tension clock") underlie the mechanism of automation. It's the depolarizing current activated during hyperpolarization. Therefore, when the guts cells recover, it's activated, the cell …
Published in Research and Reviews: A Journal of Medicine Read article
-
Molecular Docking studies of Benzodiazepine Derivatives With GABA(B) Receptor
Abstract: Benzodiazepines (BZDs) are pharmacologically significant compounds that act by binding to GABA A neurotransmitter receptors, subsequently augmenting GABA-induced chloride ion flux, consequently inducing neuronal hyperpolarization. Benzodiazepines are commonly used in the treatment of sleep disorders, anxiety, muscle spasms, seizure disorders, and some forms of depression. The primary inhibitory neurotransmitter, GABA, functions on two types of receptors: the ligand-gated GABA A/C receptors and the G protein-coupled GABA B receptors. These neurotransmitters …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 1–14 Read article