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64 articles for “gene expression regulation”
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Long Non-Coding RNAs: Key Regulators of Gene Expression in Development and Disease
Abstract: Long non-coding RNAs (lncRNAs) are RNA molecules that do not make proteins but are essential for controlling how genes are turned on or off in the body. These molecules help with various biological functions, such as guiding cell growth, shaping development, and influencing the progression of diseases. Recent advancements in genomics and transcriptomics have revealed the vast and complex roles of lncRNAs, with an increasing recognition of their involvement in …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 11–15 Read article
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Regulation of Gene Expression by Phytochrome
Abstract: AbstractThis review deals with the mechanism of Phytochrome action in regulating the expression of other genes. The PhyA and PhyB genes have the overlapping roles or there must be another Phytochrome species which are involved in the Phytochrome induction of CAB expression in these etiolated seedlings when they are exposed to red light. Double mutation of PhyA and PhyB potentially lowered the level of CAB mRNA in etiolated seedlings of …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 3, Issue 1, 2014 · pp. 20–28 Read article
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Nutritional Modulation of Gene Expression: Insights from SNPs, CNVs, and Microsatellite Markers in Animal Systems
Abstract: Nutritional modulation of gene expression represents a critical interface between diet and the genome, shaping metabolic efficiency, health, and productivity in animal systems. Genetic variations such as single nucleotide polymorphisms (SNPs), copy number variants (CNVs), and microsatellite markers contribute to differential gene regulation in response to dietary inputs. This review synthesizes current knowledge on how these molecular markers influence nutrient driven gene expression and phenotypic outcomes in livestock species. SNPs …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 2, 2026 Read article
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Flavonoids Attenuate Airway Mucin Expression, Production and Secretion Induced by Various Inducers
Abstract: Muco-obstructive respiratory disease is caused by changing normal biophysical properties of mucus including alteration of mucin concentration, ion composition and airway surface hydration. Flavonoids are one type of polyphenols which regulate mucin gene expression and consequently inhibit mucus secretion. Thus, this review aimed to discuss the effects of different flavonoids on regulation of various airways mucin gene expression and inhibition of the production of a major airway mucin core protein …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 2, 2019 · pp. 1–13 Read article
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Epigenetic Modifications in Health, Disease, and Precision Therapeutics (From Genome to Epigenome)
Abstract: Introduction: Epigenetic alterations play a crucial role in regulating gene expression in both normal physiological and disease states. These reversible modifications—such as DNA methylation, histone acetylation, phosphorylation, ubiquitination, and chromatin remodelling—are increasingly implicated in complex diseases including cancer and neurodegenerative disorders. Despite advances in standard therapeutic approaches, patient responses remain variable, largely due to genetic heterogeneity and epigenetic dysregulation. This highlights the need for incorporating epigenetic understanding into personalized medicine. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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Photoreceptor Dynamics: Light Sensing and Cellular Responses for Photochemistry
Abstract: Photoreceptor dynamics represent a fundamental aspect of photochemistry, encompassing the mechanisms by which biological systems detect and respond to light stimuli. Photoreceptors are specialized proteins that undergo structural and functional changes upon photon absorption, initiating a cascade of molecular events that translate light signals into cellular responses. These proteins are ubiquitous across life forms, including microbial rhodopsins, plant phytochromes, and animal opsins, each finely tuned to specific wavelengths and light …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 2, 2025 · pp. 28–32 Read article
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Paternal Pre-Pubertal Smoking: Small RNAs, Lasting Marks, and the Hidden Legacy of Early Exposure
Abstract: While the negative effects of maternal smoking during pregnancy are well-established, the lasting and transgenerational impact of paternal pre-pubertal smoking remains a critical, underexplored area. Emerging evidence in sperm epigenetics suggests that cigarette exposure during early male development may create persistent molecular imprints that can affect the health of future offspring. This phenomenon is rooted in the fact that heredity extends beyond the DNA sequence. Sperm carry a complex epigenetic …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 1–5 Read article
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RNA- Based Drug Delivery, Current Advances, Pharmaceutical Applications, and Future Perspectives
Abstract: RNA-based therapeutics have emerged as a transformative approach in modern medicine due to their ability to regulate gene expression with high specificity and precision. Advances in molecular biology, RNA chemistry, and nanotechnology have accelerated the development of diverse RNA modalities, including messenger RNA (mRNA), small interfering RNA (siRNA), microRNA (miRNA), antisense oligonucleotides (ASOs), and RNA aptamers. These therapeutics offer promising strategies for the treatment of cancer, genetic disorders, infectious diseases, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 27–41 Read article
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Bacillus amyloliquefaciens: A Review
Abstract: Bacillus amyloliquefaciens is one of the many Bacillus species which is used as a probiotic, exerting health benefits to the host. B. amyloliquefaciens is a gram-positive, rod shaped bacteria with peritrichous flagella. The species also produces enzymes viz. cellulases, amylases, and proteases, which aid in digestion. The species is principally utilized as a feed additive substance for domestic animals and birds. It is gaining importance as plant growth promoter rhizobacteria …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 1, 2021 · pp. 9–17 Read article
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An Approach to Design a Compiler in Context of Lexical Analyzer (Scanner) and Parser Generation (Parser) Followed by Non-optimized Intermediate Code Generation using Compiler Construction Tools
Abstract: It is very tedious and lengthy task to write a compiler. To realize the various phases of compilers we can use some specific tools. These tools are called compiler construction tools. Furthermore, we call it as compiler-compiler, compiler-generators, or translator writing system. A mixture of compiler building tools are Scanner generator —it generates lexical analyzers. The patterns specified to these generators are in the type of regular expressions. The LINUX …
Published in Journal of Advances in Shell Programming · Vol. 1, Issue 1, 2014 · pp. 1–8 Read article
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MicroRNAs in Animal Behavior: Regulation of Memory and Decision-Making in Mammals
Abstract: MicroRNAs are small, non-coding RNA molecules that play a crucial role in post-transcriptional regulation of gene expression. In recent years, their significance has extended beyond cellular development and disease regulation, as emerging evidence suggests they are critical mediators in complex behavioral processes, including learning, memory, and decision-making. This article explores the role of miRNAs in regulating neural plasticity and cognitive functions in mammals, emphasizing their involvement in memory formation and …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 3, 2024 · pp. 21–25 Read article
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To Find the Genes in the Arabidopsis thaliana at NCBI
Abstract: *Author for CorrespondenceNavni BajpaiE-mail: Navni.bajpai@gmail.com 1,2M.sc Biotechnology, Department of Bioscience, Institute of Management Studies, Ghaziabad U.P., India Received Date: January 28, 2022Accepted Date: March 02, 2022Published Date: March 12, 2022 Citation: Navni Bajpai, Sanjeev Singh. To Find the Genes in the Arabidopsis thaliana at NCBI. Research & Reviews: Journal of Computational Biology. 2021; 10(2): 16–19p.The SET domain is a conserved amino acid motif that is present in chromosomal proteins and …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 2, 2021 · pp. 16–19 Read article
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An Overview on Bioinformatics and its Application
Abstract: Bioinformatics has become an important part of many areas of biology. The term ‘Bioinformatics’ was coined by Paulien Hogeweg in 1979. In experimental molecular biology, bioinformatics techniques such as image and signal processing allow extraction of useful results from large amounts of raw data. In the field of genetics and genomics, it aids in sequencing and annotating genomes and their observed mutations. It plays a role in the text mining …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 3, Issue 2, 2016 · pp. 8–14 Read article
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Unravelling the Environment, Aroma, and Molecular Effects on Mood Fluctuations: A Review
Abstract: The ebb and flow of human emotions encompass a complex interplay of molecular processes governing mood fluctuations. This comprehensive review navigates the intricate realm of neurotransmitters, neuroplasticity, hormonal influences, genetics, and inflammation to unravel the molecular tapestry that shapes our emotional states. Foundational to mood regulation are neurotransmitters – serotonin, dopamine, and norepinephrine – orchestrating delicate balances within neural circuits. Recent molecular neuroscience elucidates their receptor pathways and signaling cascades, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 14–20 Read article
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Whispers of the Microbial World: Unveiling Bacterial Dialogues through Quorum Sensing
Abstract: Quorum sensing is a special way of bacteria by which they can regulate their own gene expression as per the population density of the bacteria. It is basically a type of cell-to-cell communication pathway used by the microbes. The signal molecule which helps in this mechanism are called auto inducer(AI). As the mechanism depends by changes in the cell density, so when the cell density reaches to the threshold cell …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article
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Rumen Microbial Adaptation to Dietary Shifts: Mechanisms, Challenges, and Implications for Sustainable Ruminant Production
Abstract: Rumen microbiota play a central role in the digestion and fermentation of dietary components, directly influencing the health and productivity of ruminants. Dietary shifts, such as transitioning from forage-based diets to concentrate-rich diets or incorporating feed additives, induce significant changes in the composition, structure, and functional dynamics of the rumen microbial community. These adaptations, while essential for maintaining microbial homeostasis, can also lead to transient imbalances, including risks of acidosis, …
Published in Research & Reviews : Journal of Ecology · Vol. 15, Issue 1, 2026 · pp. 17–26 Read article
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Modulation of Receptor Proteins: A Recent Paradigm in Drug Discovery and Target
Abstract: The main aim in drug discovery is to design different ligands those work on specific drug targets. However, various effective drugs work through the modulation of many proteins than single target. Advancement in system biology are establishing a phenotypic strength and a network structure, which suggests that, the excellent selective compounds may be performed less than desired clinical efficacy in comparison to multi-target drugs. In this new appreciation of the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 14–24 Read article
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Induction of Apoptosis using Gene Therapy in the Treatment of Cancer
Abstract: Gene therapy is the treatment of a genetic disease through the insertion of normal or genetically altered genes into cells in order to replace or make up for the non-functional or missing genes. A major application of gene therapy is the induction of apoptosis to inhibit metastases or cure cancer. Besides the identification of the target site, the choice of a suitable vector system for gene delivery is also critical …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 2, Issue 3, 2013 · pp. 6–10 Read article
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Flavonoids Regulate Airway MUC5AC Mucin Expression through Modulation of Multiple Signalling Pathways
Abstract: Airway mucus is a component of pulmonary innate immune function and plays very important role in defense against invading pathogenic microbes, chemicals and particles. The protective function of airway mucus is attributed to the viscoelasticity of mucins. Mucins are large glycoproteins play important role in cell–cell adhesion, airways protection, Nuclear-factor kappa B signalling, epidermal growth factor receptor signalling. Eleven mucin genes (among twenty identified mucin genes) have been expressed at …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 3, 2017 · pp. 21–33 Read article
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Molecular Docking of Nigella Sativa Phytocompound as Inhibitors of Transcription Factors NF-KB Implicated in Rheumatoid Arthritis
Abstract: Objectives: Nigella sativa, a plant considered around the world as the most treasured nutrient-rich herb for centuries together in different civilizations, is exceptionally known for its high levels of antioxidant properties. Free radical intensification due to oxidative stress plays a key role in the pathogenesis of rheumatoid arthritis by activating the NF-KB protein that regulates the expression of the genes involved in inflammation. Methods: This study involves in-silico approach to …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 42–55 Read article