To Find the Genes in the Arabidopsis thaliana at NCBI

Navni Bajpai

Abstract

*Author for CorrespondenceNavni BajpaiE-mail: Navni.bajpai@gmail.com 1,2M.sc Biotechnology, Department of Bioscience, Institute of Management Studies, Ghaziabad U.P., India Received Date: January 28, 2022Accepted Date: March 02, 2022Published Date: March 12, 2022 Citation: Navni Bajpai, Sanjeev Singh. To Find the Genes in the Arabidopsis thaliana at NCBI. Research & Reviews: Journal of Computational Biology. 2021; 10(2): 16–19p.The SET domain is a conserved amino acid motif that is present in chromosomal proteins and is involved in the epigenetic regulation of gene expression. Drosophila members E (Z), TRX, ASH1, and SU (VAR) 39 have categorised these proteins into four types. In yeast and mammals, homologs in all four classes have been found, but not in plants. The Arabidopsis genome was screened using BLASTP, and 37 genes were discovered. Su (var) 39 has 3 E (z) homologs, 5 trx homologs, 4 ash1 homologs, and 15 genes in common. Trx-related genes were allocated to seven genes, while ash1-related genes were assigned to three. Only four genes have previously been identified. The proteins are classified using SET domains, cysteinerich regions, and other conserved domains, including an unique YGD domain. At least 29 of the genes are active in various tissues, according to RT–PCR studies, cDNA cloning, and matching ESTs. The plant's broad genome duplication may explain the high number of SET domain genes in Arabidopsis, which may be important in epigenetic control of gene activity during plant development. In addition, the absence of introns in the coding area of eight SU(VAR)39 class genes suggests that additional genes have evolved through retrotransposition. Many proteins have been shown to have putative nuclear localization signals and AThooks, which supports the expected nuclear localization that has been demonstrated for a few proteins.

Abstract

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