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126 articles for “antibiotic”
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Evaluating the Use of Antibiotic Prophylaxis in Surgical Procedures: A Study Conducted at a Tertiary Care Teaching Hospital in Southern India
Abstract: Background: Prophylactic antibiotics can reduce the frequency of postoperative wound infections. Well-designed trials have demonstrated that the appropriate administration of prophylactic antibiotics in surgeries can reduce postoperative infections to about one-half of the incidence in untreated patients. Objectives: To examine surgeon's adherence to the hospital's antibiotic policy by comparing and assessing the usage of antibiotics as prophylactic before surgery. Methods: A prospective observational study was carried out among inpatients in …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 7–17 Read article
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Isolation, Purification, and Identification of Antibiotic-Resistant Bacterial Strain from Food Stuffs
Abstract: The widespread presence of bacteria in foodstuffs poses significant trouble to health and food safety. Pathogens in consumable products increases the transmission of resistance genes to human, potentially compromising the efficacy of conventional antibiotics. This study aims to isolate, purify, and identify antibiotic-resistant bacterial strains from food items, meals, and vegetables. The investigation employed selective culture techniques, antibiotic susceptibility assays, and molecular identification methods to detect and characterize resistant strains. …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 2, 2026 · pp. 37–45 Read article
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Meta-Analysis on Antibiotic Resistance and Its Irrational Use in India: Need of Antibiotic Stewardship Program Implementation
Abstract: Antibiotic resistance is a major health issue in developing countries. This issue is increasing exponentially due to increased consumption, easy availability of medicine and higher incidence of inappropriate use. Moreover, India stands as one among the highest infectious disease burdened country in the world. This study aims to conduct a statistical analysis to find the association between antibiotic resistance and its irrational use in India. Thereby, emphasizing the need for …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 6–14 Read article
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Antibiotics – Challenges in our Post-COVID Era
Abstract: Accidental discovery of the antibiotic properties of penicillin marked a watershed moment in healthcare, transforming the landscape of medicine and saving countless lives of injured and infected. Further research and awareness on the advantages of this “miracle drug” resulted in its bulk production in the 1940s, and played a crucial role in saving lives of thousands during World War II. Subsequent discoveries especially broad-spectrum antibiotics paved the way for further …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 1–5 Read article
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The Burden of Empirical Therapy: Analyzing the Predominance of Broad-Spectrum Antibiotic Usage in Lower Respiratory Tract Infections
Abstract: Lower respiratory tract infections (LRTIs) remain one of the leading causes of morbidity and hospitalization worldwide, particularly among older adults, immunocompromised individuals, and patients with chronic respiratory disorders. These infections include conditions such as community-acquired pneumonia, hospital-acquired pneumonia, bronchitis, and acute infective exacerbations of chronic lung disease, all of which often require rapid clinical intervention. Because microbiological confirmation of the causative pathogen frequently takes 48–72 hours, clinicians generally initiate empirical …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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Antibiotics in the Modern Era: Challenges, Misuse, and the Fight Against Resistance
Abstract: Overuse and inappropriate use of antibiotics in human medicine, agriculture, and environmental pollution. It is one of the biggest public health risks of the 21st century. The discovery of new antibiotics slowdown and the emergence of multidrug-resistant (MDR) microorganisms has highlighted the urgent need to Creative approaches to fighting opposition. This review explores the current challenges in antibiotic use, the factors driving resistance, and the strategies being implemented to address …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 57–70 Read article
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Post-Antibiotic Gut Microbiota Recovery in the Rumen: Insights into Colonization Patterns, Population Density, and Diversity Dynamics
Abstract: The post-antibiotic recovery of gut microbiota represents a critical area of research in understanding how microbial communities rebalance and re-establish homeostasis following antibiotic-induced disruptions. Antibiotics, while effective against infections, can cause substantial shifts in gut microbiota, leading to dysbiosis – a state of microbial imbalance that impairs gut health and functions. This recovery process involves multiple complex dynamics, including colonization patterns, population density, and the restoration of microbial diversity. The …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–17 Read article
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Antibiotic Resistance: Molecular Mechanisms of Resistance
Abstract: Antibiotics are called as ‘Wonder Drugs’, the miracles of modern sciences. They help combat bacteria and prevent their growth. But due to unmonitored and uncontrolled consumption of these antibiotics, there is an emergence of antibiotic resistance. This has led to a series of downfall in the therapeutic potency and efficacy of many drugs. More and more bacteria are becoming Multi-Drug Resistant (MDR); such highly resistant strains of certain bacteria are …
Published in Research and Reviews: A Journal of Microbiology and Virology Read article
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Prolonged Antibiotic Use and Reproductive Challenges in Dairy Cows: Implications for Ovarian, Uterine, and Overall Reproductive Health
Abstract: The widespread use of antibiotics in dairy farming has raised concerns regarding its potential impact on reproductive performance. Prolonged antibiotic administration can disrupt endocrine regulation, alter ovarian function, impair uterine health, and compromise overall fertility in dairy cows. This review explores the multifaceted consequences of antibiotic exposure on reproductive physiology, highlighting its effects on hormonal balance, follicular dynamics, uterine microbiota, and embryo viability. Antibiotics may induce hormonal imbalances that interfere …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 22–40 Read article
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Evaluating the Role of Pharmacists in Managing Antibiotic Use and Combating Multi-Drug Resistance in Hospital Settings
Abstract: Antibiotic resistance is now one of the crucial health issues of the world, especially in hospitals where high usage of antimicrobials is increasing the rate at which multi-drug resistant (MDR) organisms appear. Misprescription, extended treatment, and over-use of broad spectrum antibiotics play a large role in the development of resistance resulting in the growth of morbidity, mortality and health care expenditure. This review analyses the essentiality of pharmacists in controlling …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 12–19 Read article
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Bacteriophage Therapy in Dairy Farming: A Potential Alternative to Antibiotics
Abstract: The widespread use of antibiotics in dairy farming to control bacterial infections has led to significant challenges, including the emergence of antibiotic-resistant bacteria and concerns over antibiotic residues in milk. Consequently, there is an increasing demand for alternative approaches to control bacterial infections in dairy cattle. One promising solution is bacteriophage therapy, which uses viruses that selectively infect and destroy bacteria. As a result, the need for new strategies to …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 2, 2024 · pp. 1–5 Read article
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A study on Antibiotic Resistance: An Analysis of Molecular Mechanisms and Therapeutic Implications
Abstract: Antibiotic resistance (AR) represents one of the most critical existential threats to global public health, rapidly eroding the efficacy of established antimicrobial therapies and portending a return to the pre-antibiotic era. This analysis explores the intricate molecular landscape defining this crisis, focusing specifically on the primary mechanisms of action (MoA) utilized by major antibiotic classes—including cell wall inhibitors, protein synthesis inhibitors, and nucleic acid synthesis inhibitors—and the corresponding, diverse mechanisms …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 9–21 Read article
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Antibiotic Residues in Broiler Meat: Challenges for Food Safety, Public Health, and Sustainable Broiler Farming Issues
Abstract: Antibiotic residues in broiler meat pose significant risks to food safety, public health, and the sustainability of poultry farming. The use of antibiotics in broiler production, both for therapeutic and prophylactic purposes, has led to the accumulation of residues in meat, which can contribute to the development of antimicrobial resistance (AMR). This paper explores the various potential sources of antibiotic residues in broiler meat, including feed-related factors, water contamination, injection …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 1, 2025 · pp. 77–90 Read article
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A study of The impact of Antibiotic Pollution and The types of Environmental Pollution It causes
Abstract: Antibiotics are essential biological drugs for human health and are the cornerstone of treating infections caused by various bacteria and viruses. However, they also pose a significant risk if misused, as each antibiotic is designed for a specific type of bacteria. Sometimes, due to the evolution of bacteria, many antibiotics have become ineffective and resistant to contamination and infection. Therefore, they can have the opposite effect, polluting the environment instead …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 41–46 Read article
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Unveiling the Silent Threat: The Escalation and Defence Against Antibiotic Resistance
Abstract: The global challenge of antibiotic resistance presents a significant risk to public health, driven by multifaceted factors worldwide. This issue, akin to the impacts of climate change, requires concerted efforts at national and international levels to mitigate its consequences. Antibiotics have revolutionized modern medicine, enabling critical interventions like surgeries, transplants, and cancer treatments. However, without global collaboration, we face significant setbacks across medical, social, and economic domains. Initiatives to address …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–26 Read article
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The Dual Crisis: Antibiotic Resistance and the Discovery Void – A Review of Novel Therapeutic Strategies and Non-Traditional Approaches
Abstract: The global rise of antimicrobial resistance (AMR) has emerged as one of the most critical public health challenges of the 21st century, threatening to undermine decades of therapeutic success and rendering conventional antibiotic regimens increasingly ineffective. Parallel to the escalating resistance rates is a profound “discovery void,” characterised by a steep decline in the development of new antibiotic classes since the late 20th century. Together, these two interconnected crises create …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 47–65 Read article
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Influence of Antibiotic Promotion Practices on Pharmacovigilance and Resistance Reporting Patterns
Abstract: The global escalation of antimicrobial resistance (AMR) has emerged as a critical public health crisis, undermining decades of therapeutic advancements. While inappropriate prescribing and misuse of antibiotics are widely acknowledged contributors, the role of pharmaceutical promotion practices remains underexplored in influencing prescribing behaviors and downstream pharmacovigilance systems. This review critically examines how antibiotic promotion strategies – ranging from direct physician engagement to digital marketing – affect adverse drug reaction (ADR) …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 1–11 Read article
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Antibiotic Resistance Profiles of Salmonella Isolated from Al-Gharraf River and Iraqi Sewage
Abstract: Salmonella is a Gram-negative bacterium belonging to the Enterobacteriaceae family. It has a rod-shaped (bacillus) structure. Salmonella is a prominent contributor to gastrointestinal sickness worldwide. In addition, it is the causative agent of more systemic severe disorders such as typhoid and paratyphoid fevers. Salmonella is primarily recognized as pathogens transmitted by water and food to people and animals. Salmonella is often found in water-related epidemics, even though it is routinely …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
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Antimicrobial Peptides and Bacteriophages as Next-Generation Alternatives to Conventional Antibiotics
Abstract: The growing threat of antibiotic-resistant bacteria has underscored the urgent need for innovative alternatives to conventional antibiotics. Antimicrobial peptides (AMPs) and bacteriophages are gaining recognition as next-generation therapeutics due to their distinct mechanisms of action and ability to target resistant pathogens effectively. AMPs, which can be natural or synthetic, disrupt microbial membranes and offer broad-spectrum antimicrobial activity with a reduced likelihood of resistance development. Bacteriophages, as bacteria-specific viruses, provide precise …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 9–27 Read article
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Comparative Evaluation of the Use of LSTR with Double Antibiotic Paste Versus Zinc Oxide Eugenol as Obturating Material in Primary Teeth Pulpectomy
Abstract: The management of infected primary teeth is a vital aspect of pediatric dentistry, with the primary objective being the retention of the tooth in the oral cavity until its natural exfoliation. Preserving the health, structure, and appearance of primary teeth is essential for ensuring the correct eruption and alignment of permanent teeth. Pulpectomy has traditionally been the preferred treatment for primary teeth with irreversible pulp damage. Traditionally, Zinc Oxide Eugenol …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 3, 2025 · pp. 1–5 Read article